Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2018
Orientation and property of fibers of the myodural bridge in humans
Nan Zheng, Yan-Yan Chi, Xiao-Han Yang, Nan-Xing Wang, Yi-Lin Li, Yang-Yang Ge, Lan-Xin Zhang, Tai-Yuan Liu, Xiao-Ying Y…The myodural bridge is a fibrous connection between the deep suboccipital muscles of the neck and the spinal dura mater, the tough outer covering of the spinal cord. In this anatomical study, researchers investigated th…
Atlanto-axial interspace; Atlanto-occipital interspace; Collagen I fibers; Histologic staining; Myodural bridge; Suboccipital muscles; Vertebral dural ligament - A2018
A New Concept of Biotensegrity Incorporating Liquid Tissues: Blood and Lymph
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Roberto CastagnaThis conceptual article proposes an update to the biotensegrity model, which traditionally focuses on the solid structures of the fascial system. The authors argue that "liquid tissues" like blood and lymph should also…
fasciaChiropracticManual TherapyMyofascialOsteopathic - A2018
Chest pain in patients with COPD: the fascia’s subtle silence
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Roberto CastagnaIn this article, the authors discuss potential causes of chest pain in patients with chronic obstructive pulmonary disease (COPD). They highlight that chest pain is common in COPD and propose that an often-overlooked so…
fasciadiaphragmmuscle painCOPDthoracic pain - A2018
Metabolic acidosis and the role of unmeasured anions in critical illness and injury
Tobias Zingg, Bishwajit Bhattacharya, Linda L MaerzIn this review article, the authors discuss metabolic acidosis, a common condition in critically ill patients that is associated with increased mortality. A significant component of this acidosis can be caused by so-cal…
Metabolic acidosisUnmeasured anionsStrong ion differenceStrong ion gapAnion gap Base excess - A2018
Fasciae of the musculoskeletal system: normal anatomy and MR patterns of involvement in autoimmune diseases
Thomas Kirchgesner, Xavier Demondion, Maria Stoenoiu, Patrick Durez, Adrien Nzeusseu Toukap, Frédéric Houssiau, Christi…This review article describes the fascial system as a three-dimensional continuum of connective tissue found throughout the body. The authors review the normal anatomy of fascia and its appearance on magnetic resonance…
fasciaMusculoskeletalAnatomyAutoimmuneMRI - A2018
Fascial preadipocytes: another missing piece of the puzzle to understand fibromyalgia?
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Francesca Cavallaro, David LintonbonIn this review paper, the authors discuss fibromyalgia, a chronic pain condition whose cause remains uncertain. While often linked to changes in the central nervous system, research also points to peripheral nerve damag…
fasciaFibromyalgiapainMyofascialneuropathic pain - A2018
Pathobiology of cigarette smoke-induced invasive cancer of the renal pelvis and its prevention by vitamin C
Shinjini Ganguly, Ayan Chandra, Indu B ChatterjeeIn this animal study, researchers investigated how cigarette smoke might cause invasive cancer of the renal pelvis and if vitamin C could offer protection. They found that when guinea pigs were exposed to cigarette smok…
Invasive cancer of the renal pelvis Cigarette smoke Vitamin C Oxidative damage Persistent EGFR signaling Cell cycle deregulation - A2018
Measuring the Human Ultra-Weak Photon Emission Distribution Using an Electron-Multiplying, Charge-Coupled Device as a Sensor
Fernando Ortega-Ojeda, Matías Calcerrada, Alejandro Ferrero, Joaquín Campos, Carmen Garcia-RuizLiving systems, including humans, emit an extremely faint light called ultra-weak photon emission (UPE). This light is thought to be a byproduct of metabolic processes, particularly those involving reactive oxygen speci…
ultra-weak photon emission; spectrometer; measurement; electron multiplying charge coupled device sensor; liquid crystal tunable filter - A2018
Mineralization can be an incidental ultrasonographic finding in equine tendons and ligaments
Etienne J O O'Brien, Roger K W SmithIn this observational study on horses, researchers investigated the presence of mineralization, or calcium deposits, in tendons and ligaments using ultrasound. They found it was most common in the deep digital flexor te…
horsecalcificationDopplerossification - A2018
Neuroinflammation and central sensitization in chronic and widespread pain
Ru-Rong Ji, Andrea Nackley, Yul Huh, Niccolò Terrando, William MaixnerChronic pain is partly maintained by central sensitization, a state where the nervous system becomes hypersensitive. This review discusses how neuroinflammation—inflammation in the nervous system—contributes to this pro…
inflammationchronic paainneuroinflammationsensitization - A2018
Fascial well-being: Mechanotransduction in manual and movement therapies
Leon ChaitowThis article discusses mechanotransduction, the process by which cells in connective tissue sense and respond to mechanical forces like stretch, compression, and shear. Specialized cells such as fibroblasts communicate…
mechanotransduction - A2017
The significance of closed kinematic chains to biological movement and dynamic stability
Stephen Levin, Susan Lowell de Sol!orzano, Graham ScarrBiomechanical research has long focused on the body as a system of levers, but this review highlights the importance of "closed kinematic chains" (CKCs). These are continuous mechanical loops that couple multiple parts…
biotensegrityBiomechanicsClosed-chainDevelopmentEvolution