Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+2023
A New Player in the Mechanobiology of Deep Fascia: Yes-Associated Protein (YAP)
Carmelo Pirri, Brasilina Caroccia, Andrea Angelini, Maria Piazza, Lucia Petrelli, Ilaria Caputo, Chiara Montemurro, Pie…This study investigated the role of Yes-associated protein (YAP) in the mechanobiology of deep fascia, specifically the thoracolumbar fascia. Researchers analyzed tissue samples from patients and found that YAP acts as…
fascia; thoracolumbar fascia; extracellular matrix; fibroblasts; Yes-associated protein (YAP); remodeling - A+2023
The Combined Effect of Static Stretching and Foam Rolling With or Without Vibration on the Range of Motion, Muscle Performance, and Tissue Hardness of the Knee Extensor
Masatoshi Nakamura, Andreas Konrad, Kazuki Kasahara, Riku Yoshida, Yuta Murakami, Shigeru Sato, Kodai Aizawa, Ryoma Koi…This study investigated how the order of static stretching (SS) and foam rolling (FR), with or without vibration, affects range of motion, muscle strength, and tissue hardness in the quadriceps. The results showed that…
range of motionFoam rollingPerformancestatic stretching - A+2021
Menopause, Ultraviolet Exposure, and Low Water Intake Potentially Interact with the Genetic Variants Related to Collagen Metabolism Involved in Skin Wrinkle Risk in Middle-Aged Women
Sunmin Park, Suna Kang, Woo Jae LeeThis observational study of 128 middle-aged women examined how genetic variants related to collagen metabolism interact with lifestyle factors to influence wrinkle development. Researchers found that women with a high p…
COL17A1; EGFR; MMP16; UV exposure; genetic variants; wrinkle. - A+2021
Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19
Yun Kit Yeoh, Tao Zuo, Grace Chung-Yan Lui, Fen Zhang, Qin Liu, Amy Y L Li, Arthur C K Chung, Chun Pan Cheung, Eugene Y…Researchers investigated the link between the gut microbiome and the severity of COVID-19. In this cohort study, they analyzed stool and blood samples from 100 patients and compared them to individuals without COVID-19.…
colonic bacteria; colonic microflora; inflammation - A+2021
Hyaluronic Acid in Postmenopause Vaginal Atrophy: A Systematic Review
Carlos Campagnaro M Dos Santos, Maria Laura R Uggioni, Tamy Colonetti, Laura Colonetti, Antonio José Grande, Maria Inês…This systematic review evaluated the effectiveness of hyaluronic acid as a treatment for vaginal atrophy in postmenopausal women. By analyzing five primary studies, researchers found that hyaluronic acid appears to offe…
Hyaluronic Acid; Postmenopause; Systematic Review; Vaginal Atrophy - A+2021
Time-Restricted Eating, Intermittent Fasting, and Fasting-Mimicking Diets in Weight Loss
Maura Fanti, Amrendra Mishra, Valter D Longo, Sebastian BrandhorstThis literature review examines the effects of time-restricted eating (TRE), intermittent fasting (IF), and fasting-mimicking diets (FMD) on weight loss. While these interventions are popular for their potential health…
Fasting-mimicking diet; Intermittent fasting; Obesity; Time-restricted eating; Weight loss - A+2021
Vascular Stiffness in Aging and Disease
Stephen F Vatner, Jie Zhang, Christina Vyzas, Kalee Mishra, Robert M Graham, Dorothy E VatnerThis narrative review examines how vascular stiffness, particularly in the aorta, increases with age and contributes to various cardiovascular diseases. Research suggests that stiffness often progresses more significant…
aging; aortic stiffness; cardiovascular diseases; human; non-human primate - A+2021
Prevalence and risk factors for menopausal symptoms in middle-aged Chinese women: a community-based cross-sectional study
Xueyin Wang, Linhong Wang, Jiangli Di, Xiaosong Zhang, Gengli ZhaoThis community-based cross-sectional study examined the prevalence of menopausal symptoms among over 6,000 middle-aged Chinese women. The findings indicate that symptoms are most prevalent during the menopausal transiti…
Menopausal symptoms – Menopause – Perimenopause – Postmenopause – Risk factors - A+2020
Long-term effects of resveratrol on cognition, cerebrovascular function and cardio-metabolic markers in postmenopausal women: A 24-month randomised, double-blind, placebo-controlled, crossover study
Jay Jay Thaung Zaw, Peter R C Howe, Rachel H X WongThis 24-month randomized, double-blind, placebo-controlled crossover study investigated the effects of daily resveratrol supplementation in 125 postmenopausal women. The researchers found that regular intake of 75 mg re…
Resveratrolsupplementation - A+2020
Narrative review of the epidemiology, diagnosis and pathophysiology of pelvic organ prolapse
Adi Y Weintraub, Hannah Glinter, Naama Marcus-BraunThis narrative review examines the epidemiology and causes of pelvic organ prolapse (POP), a condition affecting many women's quality of life. The authors highlight a discrepancy in prevalence rates, noting that while a…
Epidemiology; Pelvic Organ Prolapse; physiopathology - A+2020
The Rolf Method of Structural Integration and Pelvic Floor Muscle Facilitation: Preliminary Results of a Randomized, Interventional Study
Martyna Kasper-Jedrzejewska, Grzegorz Jedrzejewski, Lucyna Ptaszkowska, Kuba Ptaszkowski, Robert Schleip, Tomasz HalskiThis randomized, interventional study investigated how the Rolf Method of Structural Integration (SI) affects pelvic floor muscle function in healthy women. Thirty-three women were divided into two groups; one received…
pelvic floor muscles; Structural Integration; surface electromyography - A+2020
Role of vitamin K 2 in bone metabolism: a point of view and a short reappraisal of the literature
A Capozzi, G Scambia, S Migliaccio, S LelloThis narrative review examines the role of Vitamin K2 in bone metabolism and its contribution to maintaining skeletal integrity. Vitamin K2 is essential for activating osteocalcin, a key protein that binds calcium to th…
Vitamin K2; bone; fracture; menaquinone; osteoporosis