Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+2023
The Combined Effect of Static Stretching and Foam Rolling With or Without Vibration on the Range of Motion, Muscle Performance, and Tissue Hardness of the Knee Extensor
Masatoshi Nakamura, Andreas Konrad, Kazuki Kasahara, Riku Yoshida, Yuta Murakami, Shigeru Sato, Kodai Aizawa, Ryoma Koi…This study investigated how the order of static stretching (SS) and foam rolling (FR), with or without vibration, affects range of motion, muscle strength, and tissue hardness in the quadriceps. The results showed that…
range of motionFoam rollingPerformancestatic stretching - A+2023
A New Player in the Mechanobiology of Deep Fascia: Yes-Associated Protein (YAP)
Carmelo Pirri, Brasilina Caroccia, Andrea Angelini, Maria Piazza, Lucia Petrelli, Ilaria Caputo, Chiara Montemurro, Pie…This study investigated the role of Yes-associated protein (YAP) in the mechanobiology of deep fascia, specifically the thoracolumbar fascia. Researchers analyzed tissue samples from patients and found that YAP acts as…
fascia; thoracolumbar fascia; extracellular matrix; fibroblasts; Yes-associated protein (YAP); remodeling - A+2021
Time-Restricted Eating, Intermittent Fasting, and Fasting-Mimicking Diets in Weight Loss
Maura Fanti, Amrendra Mishra, Valter D Longo, Sebastian BrandhorstThis literature review examines the effects of time-restricted eating (TRE), intermittent fasting (IF), and fasting-mimicking diets (FMD) on weight loss. While these interventions are popular for their potential health…
Fasting-mimicking diet; Intermittent fasting; Obesity; Time-restricted eating; Weight loss - A+2021
Menopause, Ultraviolet Exposure, and Low Water Intake Potentially Interact with the Genetic Variants Related to Collagen Metabolism Involved in Skin Wrinkle Risk in Middle-Aged Women
Sunmin Park, Suna Kang, Woo Jae LeeThis observational study of 128 middle-aged women examined how genetic variants related to collagen metabolism interact with lifestyle factors to influence wrinkle development. Researchers found that women with a high p…
COL17A1; EGFR; MMP16; UV exposure; genetic variants; wrinkle. - A+2021
Prevalence and risk factors for menopausal symptoms in middle-aged Chinese women: a community-based cross-sectional study
Xueyin Wang, Linhong Wang, Jiangli Di, Xiaosong Zhang, Gengli ZhaoThis community-based cross-sectional study examined the prevalence of menopausal symptoms among over 6,000 middle-aged Chinese women. The findings indicate that symptoms are most prevalent during the menopausal transiti…
Menopausal symptoms – Menopause – Perimenopause – Postmenopause – Risk factors - A+2021
Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19
Yun Kit Yeoh, Tao Zuo, Grace Chung-Yan Lui, Fen Zhang, Qin Liu, Amy Y L Li, Arthur C K Chung, Chun Pan Cheung, Eugene Y…Researchers investigated the link between the gut microbiome and the severity of COVID-19. In this cohort study, they analyzed stool and blood samples from 100 patients and compared them to individuals without COVID-19.…
colonic bacteria; colonic microflora; inflammation - A+2021
Vascular Stiffness in Aging and Disease
Stephen F Vatner, Jie Zhang, Christina Vyzas, Kalee Mishra, Robert M Graham, Dorothy E VatnerThis narrative review examines how vascular stiffness, particularly in the aorta, increases with age and contributes to various cardiovascular diseases. Research suggests that stiffness often progresses more significant…
aging; aortic stiffness; cardiovascular diseases; human; non-human primate - A+2021
Hyaluronic Acid in Postmenopause Vaginal Atrophy: A Systematic Review
Carlos Campagnaro M Dos Santos, Maria Laura R Uggioni, Tamy Colonetti, Laura Colonetti, Antonio José Grande, Maria Inês…This systematic review evaluated the effectiveness of hyaluronic acid as a treatment for vaginal atrophy in postmenopausal women. By analyzing five primary studies, researchers found that hyaluronic acid appears to offe…
Hyaluronic Acid; Postmenopause; Systematic Review; Vaginal Atrophy - A+2020
Tissue Micro-channels Formed by Collagen Fibers and their Internal Components: Cellular Evidence of Proposed Meridian Conduits in Vertebrate Skin
Bai Xuebing, Wu Ruizhi, Zhang Yue, Liang Chunhua, Shi Yonghong, Zhang Yingxin, Ding Baitao, Imran Tarique, Yang Ping, C…This study examined fascia from various vertebrate species using microscopy to search for physical structures that might correspond to the meridian conduits described in Traditional Chinese Medicine (TCM). Researchers i…
Collagen fiberTelocyteChinese traditional medicinemeridian conduittissue micro-channel - A+2020
Regular Supplementation With Resveratrol Improves Bone Mineral Density in Postmenopausal Women: A Randomized, Placebo-Controlled Trial
Rachel H X Wong, Jay Jay Thaung Zaw, Cory J Xian, Peter R C HoweThis randomized, placebo-controlled trial investigated how daily resveratrol supplementation affects bone health in postmenopausal women. Over 12 months, participants taking 75 mg of resveratrol twice daily showed incre…
AGING; CLINICAL TRIALS; DXA; MENOPAUSE; NUTRITION - A+2020
Long-term effects of resveratrol on cognition, cerebrovascular function and cardio-metabolic markers in postmenopausal women: A 24-month randomised, double-blind, placebo-controlled, crossover study
Jay Jay Thaung Zaw, Peter R C Howe, Rachel H X WongThis 24-month randomized, double-blind, placebo-controlled crossover study investigated the effects of daily resveratrol supplementation in 125 postmenopausal women. The researchers found that regular intake of 75 mg re…
Resveratrolsupplementation - A+2020
Narrative review of the epidemiology, diagnosis and pathophysiology of pelvic organ prolapse
Adi Y Weintraub, Hannah Glinter, Naama Marcus-BraunThis narrative review examines the epidemiology and causes of pelvic organ prolapse (POP), a condition affecting many women's quality of life. The authors highlight a discrepancy in prevalence rates, noting that while a…
Epidemiology; Pelvic Organ Prolapse; physiopathology