Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+2017
Hyaluronan as a therapeutic target in human diseases
Jiurong Liang, Dianhua Jiang, Paul W NobleThis narrative review explores the role of hyaluronan, a major component of the extracellular matrix involved in tissue injury and repair. Its function varies significantly with its size; fragmented hyaluronan can promo…
hyaluronan - A+2016
The relationship between pelvic alignment and dysmenorrhea
Moon-Jeong Kim, Il-Hun Baek, Bong-Oh GooThis study investigated the relationship between pelvic alignment and dysmenorrhea (menstrual pain). Researchers compared 102 women, divided into a group with menstrual pain and a group without, using 4D imaging to meas…
AlignmentDysmenorrheaPelvic torsion - A+2016
Health E!ects of Alkaline Diet and Water, Reduction of Digestive-tract Bacterial Load, and Earthing
Haider Abdul-Lateef MousaThis narrative review discusses how an alkaline diet, alkaline water, reduced digestive-tract bacterial load, and “earthing” might counter chronic low-grade acidosis. The author synthesizes literature suggesting these a…
chronic inflammationearthinghypertensionMetabolic acidosisalkaline diet - A+2016
Oxidative stress and oocyte quality: ethiopathogenic mechanisms of minimal/mild endometriosis-related infertility
Michele Gomes Da Broi, Paula Andrea NavarroIn this review article, the authors explore the connection between mild endometriosis and infertility. Although the link is known, the exact mechanisms are not fully understood. The researchers suggest that poor oocyte…
Early endometriosis . Infertility . Oocyte quality . Oxidative stress . Follicular microenvironment - A+2016
Comparison of the Hyaluronic Acid Vaginal Cream and Conjugated Estrogen Used in Treatment of Vaginal Atrophy of Menopause Women: A Randomized Controlled Clinical Trial
Azam Jokar, Tayebe Davari, Nasrin Asadi, Fateme Ahmadi, Sedighe ForuhariThis randomized controlled clinical trial compared the effectiveness of hyaluronic acid vaginal cream with conjugated estrogen cream for treating vaginal atrophy in menopausal women. Over an eight-week period, researche…
Atrophic vaginitis; Estrogen; Hyaluronic acid; Menopause - A+2016
Piezo2 is the principal mechanotransduction channel for proprioception
Seung-Hyun Woo, Viktor Lukacs, Joriene C de Nooij, Dasha Zaytseva, Connor R Criddle, Allain Francisco, Thomas M Jessell…Proprioception is the sense of where our body parts are in space. In this animal study, researchers investigated the molecular sensor responsible for this ability in mice. They found that an ion channel called Piezo2 wa…
proprioceptionmuscle spindlespiezomechanotranductiiongolgi tendon organ - A+2016
Acute effects of muscle stretching on physical performance, range of motion, and injury incidence in healthy active individuals: a systematic review
David G Behm, Anthony J Blazevich, Anthony D Kay, Malachy McHughThis systematic review examines how different types of stretching (static, dynamic, and PNF) affect performance, range of motion (ROM), and injury risk in healthy individuals. The findings suggest that static stretching…
ballistic stretch; dynamic stretch; facilitation neuromusculaire proprioceptive; flexibility; flexibilité; proprioceptive neuromuscular facilitation; static stretch; warm-up - A+2015
Osmotic pressure induced tensile forces in tendon collagen
Admir Masic, Luca Bertinetti, Roman Schuetz, Shu-Wei Chang, Till Hartmut Metzger, Markus J Buehler, Peter FratzlResearchers investigated the role of water in tendon collagen using a combination of experiments and computer modeling. They found that water is a crucial part of the collagen molecule's structure. When water is removed…
collagenOsmotic pressurewater - A+2015
A unifying neuro-fasciagenic model of somatic dysfunction - Underlying mechanisms and treatment - Part II
Paolo TozziThis review paper proposes a new, unifying "neuro-fasciagenic" model for understanding somatic dysfunction. The author argues for a shift in perspective, moving from a purely neurological explanation to one where fascia…
fasciaManual Therapysomatic dysfunctionfascial dysfunctionfascial mechanisms - A+2015
Chondroprotection and the Prevention of Osteoarthritis Progression of the Knee
Brian Gallagher, Fotios P Tjoumakaris, Marc I Harwood, Robert P Good, Michael G Ciccotti, Kevin B FreedmanIn this systematic review, researchers evaluated whether certain medications and supplements could protect joint cartilage and slow the progression of knee osteoarthritis. By analyzing randomized controlled trials, they…
knee; articular cartilage; chondroprotection; nutraceutical - A+2015
Changes in electrical pain threshold of fascia and muscle after initial and secondary bouts of elbow flexor eccentric exercise
Wing Yin Lau, Anthony J. Blazevich, Michael J. Newton, Sam Shi Xuan Wu, Kazunori NosakaThis study investigated how pain sensitivity changes in fascia and muscle after strenuous eccentric exercise. Ten young men performed two bouts of maximal eccentric elbow curls, four weeks apart. After the first session…
pressure pain thresholdmuscle damageRepeated bout effectDelayed onset muscle sorenessVisual analogue scale - A+2015
The Heart, the Brain, and the Regulation of Emotion
Sarah N Garfinkel, Jessica A Eccles, Hugo D CritchleyThis research entry, summarized from its title, appears to explore the relationship between the heart, the brain, and how emotions are managed. It likely discusses how signals from the cardiovascular system, specificall…
psychology.psychiatryemotionsbody signals