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The Fascia Guide
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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 1–7 of 7 studiesVitamin CA++
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A++2018

Ascorbic acid in cancer treatment: let the phoenix fly

Niraj Shenoy, Edward Creagan, Thomas Witzig, Mark Levine

This review article discusses the renewed interest in Vitamin C (ascorbic acid) as a potential anti-cancer agent. When administered intravenously, Vitamin C can reach much higher concentrations in the body than when tak…

cancerVitamin Cascorbate
A++2017

Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes

Anitra C Carr, Patrice C Rosengrave, Simone Bayer, Steve Chambers, Jan Mehrtens, Geoff M Shaw

This study investigated vitamin C levels in 44 critically ill patients in an intensive care unit (ICU). Researchers found that most patients had low vitamin C levels (hypovitaminosis C), and one-third were severely defi…

Vitamin CsepsisIntensive care
A++2015

Fruit, vegetable and vitamin C intakes and plasma vitamin C: cross-sectional associations with insulin resistance and glycaemia in 9-10 year-old children

A S Donin, J E Dent, C M Nightingale, N Sattar, C G Owen, A R Rudnicka, M R Perkin, A M Stephen, S A Jebb, D G Cook, P…

This cross-sectional study of over 2000 children in the UK examined the relationship between vitamin C and risk factors for type 2 diabetes. Researchers found that higher levels of vitamin C in the blood were associated…

Vitamin Cinsulin resistensglycaemia
A++2013

Vitamin C in Disease Prevention and Cure: An Overview

Shailja Chambial, Shailendra Dwivedi, Kamla Kant Shukla, Placheril J John, Praveen Sharma

This narrative review provides an overview of Vitamin C's many roles in the body. It is essential for developing and maintaining connective tissues, and plays a key part in bone formation, wound healing, and gum health.…

cancerdiabetesVitamin C
A++1990

Immunological evidence for the accumulation of lipoprotein(a) in the atherosclerotic lesion of the hypoascorbemic guinea pig

M Rath, L Pauling

This animal study investigated the link between vitamin C, a specific cholesterol particle called Lipoprotein(a) or Lp(a), and atherosclerosis. Researchers found that guinea pigs, which like humans cannot produce their…

Vitamin CAscorbic acidAtherosclerosis
A++1978

Ascorbic acid status in idiopathic hemochromatosis

P Brissot, Y Deugnier, A Le Treut, F Regnouard, M Simon, M Bourel

This study investigated Vitamin C (ascorbic acid) levels in patients with idiopathic hemochromatosis, a condition characterized by excessive iron accumulation. The results showed that untreated patients had significantl…

Vitamin Ciron overloadHemochromatosis
A++1975

SYNTHESIS AND SOME MAJOR FUNCTIONS OF VITAMIN C IN ANIMALS

I B Chatterjee, A K Majumder, B K Nandi, N Subramanian

Vitamin C, or ascorbic acid, is essential for most living things, but some animals, including humans, cannot produce it themselves. Historically, determining an animal's ability to synthesize Vitamin C required feeding…

StressVitamin Csyntesis