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The Fascia Guide
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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 1–3 of 3 studiesManual TherapyA++
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A++2017

Biological effects of direct and indirect manipulation of the fascial system. Narrative review

Giovanni Parravicini, Andrea Bergna

This narrative review explores the biological effects of manual fascial therapies. While osteopathic manipulative treatment (OMT) is clinically effective, its underlying mechanisms are not fully understood. The authors…

fasciaMyofascial releaseManual Therapy
A++2013

Mathematical Analysis of the Flow of Hyaluronic Acid Around Fascia During Manual Therapy Motions

Max Roman, Hans Chaudhry, Bruce Bukiet, Antonio Stecco,Thomas Findley

This study used a mathematical model to simulate how different manual therapy techniques affect the flow of hyaluronic acid (HA) within fascia. The researchers compared constant sliding, perpendicular vibration, and tan…

hyaluronanfasciaManual Therapy
A++2006

Quantum Events of Biophoton Emission Associated with Complementary and Alternative Medicine Therapies: A Descriptive Pilot Study

Marius Hossu, Ronald Rupert

This descriptive pilot study investigated biophoton emission (BPE), an ultra-low level of light emitted by living organisms that may reflect overall health status. Researchers measured BPE from the neck and lower back o…

fasciaManual Therapybiophotons