Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2020
Therapeutic importance of hydrogen sulfide in age-associated neurodegenerative diseases
Rubaiya Tabassum, Na Young Jeong, Junyang JungThis narrative review explores the potential of molecular hydrogen (H2) as a preventive and therapeutic medical gas for various health conditions. H2 acts as a selective antioxidant, specifically targeting the most harm…
3-mercaptopyruvate sulfurtransferase; aging; antioxidant; cystathionine β-synthase; cystathionine γ-lyase; glutathione; hydrogen sulfide; neurodegenerative disease; oxidative stress; reactive oxygen species - A++2020
Mesothelial Cells Covering the Surface of Primo Vascular System Tissue
Chae Jeong Lim, Yeo Sung Yoon, Pan Dong RyuIn this study on rats, researchers investigated the cells on the outer surface of the primo vascular system (PVS), a proposed circulatory network. Using various microscopy and staining techniques, they identified these…
HBME-1; hematoxylin and eosin staining (H&E); periductium; primo node; primo vessel; scanning electron microscopy (SEM) - A++2020
What is the Intelligent Tissue !eory and How Does it Relate to Acupuncture?
Fletcher KovichThis article introduces the "intelligent tissue theory," which proposes that organ information is transmitted via electromagnetic waves and interpreted by bodily tissues at specific meridians. The author suggests that t…
acupunctureChiintelligent tissueNei Jing - A++2020
The Efficacy of Stretching Exercises on Arterial Stiffness in Middle-Aged and Older Adults: A Meta-Analysis of Randomized and Non-Randomized Controlled Trials
Michitaka Kato, Fumi Nihei Green, Kazuki Hotta, Toshiya Tsukamoto, Yasunari Kurita, Akira Kubo, Hisato TakagiThis meta-analysis reviewed eight studies involving 213 middle-aged and older adults to see how stretching affects arterial stiffness. The combined results suggest that regular stretching can significantly reduce arteri…
stretching exercises; arterial stiffness; endothelial function; middle-aged; older adult - A++2020
The potential of cannabidiol in the COVID-19 pandemic
Giuseppe Esposito, Marcella Pesce, Luisa Seguella, Walter Sanseverino, Jie Lu, Chiara Corpetti, Giovanni SarnelliThis scientific hypothesis explores the potential of cannabidiol (CBD) as a supportive treatment during the COVID-19 pandemic. The authors suggest that CBD may down-regulate the receptors the virus uses for cellular ent…
fibrosisCannabinoidsimmune systemCOVID-19anti-inflammatory - A++2019
Role of the immune system in vascular function and blood pressure control induced by faecal microbiota transplantation in rats
Marta Toral, Iñaki Robles Vera, Néstor de la Visitación, Miguel Romero, Manuel Sánchez, Manuel Gómez Guzmán, Alba Rodri…This animal study investigated the link between gut bacteria, the immune system, and blood pressure in rats. Researchers transplanted gut microbiota between spontaneously hypertensive rats and rats with normal blood pre…
hypertensionendothelial dysfunctiongut dysbiosisimmune cells - A++2019
The Stomach’s Communication with Its Related Acupoints, and the “Intelligent Tissue” Hypothesis
Fletcher KovichThis study explores the "intelligent tissue" hypothesis, which suggests that an organ's functional state is reflected in real-time at specific acupuncture points. By monitoring electrical impedance at six stomach-relate…
acupunctureimpedanceduodenalpacesetterslow wave - A++2019
Characterization of bony changes localized to the cervical articular processes in a mixed population of horses
Kevin K Haussler, Roy R Pool, Hilary M ClaytonThis observational cross-sectional study characterized bony changes in the cervical articular processes of 55 horses without primary complaints of neck pain. The researchers found that 72% of the examined joints exhibit…
cervical processes - A++2019
Local Vibration Stimuli Induce Mechanical Stress-Induced Factors and Facilitate Recovery From Immobilization-Induced Oxidative Myofiber Atrophy in Rats
Fusako Usuki, Masatake Fujimura, Atsushi Nakamura, Jiro Nakano, Minoru Okita, Itsuro HiguchiThis study on rats investigated whether local vibration could help muscles recover after being immobilized. Researchers put a cast on one hindlimb of the rats for a week to induce muscle atrophy. After removing the cast…
YAP1; local vibration; mechano-growth factor; mechanotransduction; oxidative myofiber atrophy; satellite cell; therapeutics. - A++2019
Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients
Stephan F E Praet, Craig R Purdam, Marijke Welvaert, Nicole Vlahovich, Gregg Lovell, Louise M Burke, Jamie E Gaida, Sil…This pilot study investigated whether supplementing with specific collagen peptides could improve symptoms for patients with chronic Achilles tendinopathy. Participants combined a calf-strengthening program with either…
achilles tendon; microvessels; contrast-enhanced ultrasound; hydrolysed collagen supplementation - A++2019
Fascial neuromodulation: an emerging concept linking acupuncture, fasciology, osteopathy and neuroscience
Gianluca BiancoThis conceptual paper presents a model called "fascial neuromodulation" to explain how therapies like acupuncture might work. The author suggests that mechanical signals through the fascial network can influence the ner…
acupunctureosteopathyneuromodulationposturologyfascial system - A++2019
Acute Effects of Static Stretching on Muscle Strength and Power: An Attempt to Clarify Previous Caveats
Helmi Chaabene, David G Behm, Yassine Negra, Urs GranacherThis narrative review examines how static stretching affects subsequent strength and power. While static stretching was once thought to hinder performance, recent evidence suggests the duration of the stretch is the cri…
physiologyrange of motioninjurypassive stretchingphysical fitness