Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2021
Physical Agent Modalities in Early Osteoarthritis: A Scoping Review
Giulia Letizia Mauro, Dalila Scaturro, Francesca Gimigliano, Marco Paoletta, Sara Liguori, Giuseppe Toro, Giovanni Iola…This scoping review investigated the role of physical agent modalities in treating early osteoarthritis (EOA). Researchers searched for studies on treatments like TENS, extracorporeal shockwave therapy (ESWT), ultrasoun…
osteoarthritis; early osteoarthritis; rehabilitation; physical therapy modalities; physical agents; electric stimulation therapy; pulsed electromagnetic field; extracorporeal shockwave therapy; vibration therapy - A++2021
Therapeutic potential of astaxanthin and superoxide dismutase in Alzheimer's disease
Vyshnavy Balendra, Sandeep Kumar SinghThis narrative review explores how the combination of astaxanthin and the enzyme superoxide dismutase (SOD) may help protect the brain in Alzheimer's disease. Oxidative stress is a key factor in the disease's progressio…
Alzheimer's disease; astaxanthin; neurodegeneration; nutraceuticals; oxidative stress; superoxide dismutase (SOD) - A++2021
Is "Delayed Onset Muscle Soreness" a False Friend? The Potential Implication of the Fascial Connective Tissue in Post-Exercise Discomfort
Jan Wilke, Michael BehringerThis narrative review explores the theory that delayed onset muscle soreness (DOMS) may originate in the connective tissue (fascia) rather than the muscle fibers themselves. While traditional explanations like lactic ac…
DOMS; athletes; eccentric exercise; fascia; pain. - A++2021
Temporomandibular Myofascial Pain Syndrome-Aetiology and Biopsychosocial Modulation. A Narrative Review
Paulina Golanska, Klara Saczuk, Monika Domarecka, Joanna Kuć, Monika Lukomska-SzymanskaThis case report examined the effectiveness of Global Postural Reeducation (GPR) in treating a 23-year-old woman with temporomandibular disorder (TMD) and postural imbalances. By addressing muscle chains and spinal alig…
biopsychosocial profile modulation; bruxism; limbic system; stress; temporomandibular myofascial pain syndrome - A++2021
Fascia The Universal Singularity Of Biotensegrity The Dark Matter Of Our Inner Cosmos
John SharkeyThis theoretical paper argues that fascia is the body's fundamental and unifying system, analogous to dark matter in the cosmos. The author suggests this continuity is evident from embryology, where the body develops as…
Embryology; Fascia; Biotensegrity; Epigenetics; DNA; Anatomy; Dissection - A++2020
Applicability of Low-intensity Vibrations as a Regulatory Factor on Stem and Progenitor Cell Populations
Oznur Baskan, Ozge Karadas, Gulistan Mese, Engin OzciviciThis narrative review explores how mechanical forces, specifically low-intensity vibrations, can influence stem cells. While high-impact activities like running are known to build tissue, they are not suitable for every…
Stem cell; biomechanics; mechanobiology; progenitor cell populations; tissue engineering; vibrations - A++2020
Telocytes and lymphatic endothelial cells: Two immunophenotypically distinct and spatially close cell entities
Irene Rosa, Mirca Marini, Eleonora Sgambati, Lidia Ibba-Manneschi, Mirko ManettiResearchers have been working to clarify the identity of two cell types, telocytes and lymphatic endothelial cells, which can sometimes look similar in tissue samples. This study used a specific staining technique to lo…
Telocytes and lymphatic endothelial cells: Two immunophenotypically distinct and spatially close cell entities - A++2020
Local low-intensity vibration improves healing of muscle injury in mice
Thomas F Corbiere, Timothy J KohIn this animal study, researchers investigated how local low-intensity vibration (LIV) affects muscle injury healing in mice. After lacerating the gastrocnemius (calf) muscle in mice, one group received daily vibration…
skeletal muscle injurycell culturemechanical stimulationmouse modelmuscle repair - A++2020
Simulation and Modeling of Telocytes Behavior in Signaling and Intercellular Communication Processes
Dragos Cretoiu, Simona Roatesi, Ion Bica, Cezar Plesca, Amado Stefan, Oana Bajenaru, Carmen Elena Condrat, Sanda Maria…Telocytes are a unique type of interstitial cell with long extensions that form networks, thought to be involved in local tissue equilibrium and regeneration. In this study, researchers used computer simulation and math…
content-based image retrieval; image indexation; modeling of living cell behavior; telocyte network tracking and indexing; telocytes; viscoelastic constitutive laws - A++2020
Biotensegrity: What is the big deal?
Graham ScarrDetails for this entry have not yet been summarized. The title, "Biotensegrity: What is the big deal?", suggests it is an explanatory or editorial piece about the concept of biotensegrity. Biotensegrity is a model that…
biotensegrity - A++2020
The potential role of cannabinoids in dermatology
Tabrez Sheriff, Matthew J Lin, Danielle Dubin, Hooman KhorasaniThis literature review explores how cannabinoids, including both plant-derived and endogenous versions, may affect the skin through the endocannabinoid system. Research suggests that the skin possesses its own receptors…
Cannabinoids in dermatology; cannabidiol; cannabis; endocannabinoids. - A++2020
Fascia and soft tissues innervation in the human hip and their possible role in post-surgical pain
Caterina Fede, Andrea Porzionato, Lucia Petrelli, Chenglei Fan, Carmelo Pirri, Carlo Biz, Raffaele De Caro, Carla SteccoResearchers investigated the nerve supply to various soft tissues in the human hip to better understand persistent pain after hip replacement surgery. Analyzing tissue samples from patients and cadavers, they measured t…
fasciapaininnervationproprioceptionSoft tissue