Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2016
Fascial hierarchies and the relevance of crossed-helical arrangements of collagen to changes in shape; part II: The proposed effect of blood pressure (Traube-Hering-Mayer) waves on the fascia
Graham ScarrPeriodic changes in blood pressure, known as Traube-Hering-Mayer waves, are linked to respiration and nervous system activity. While complex and not fully understood, they can provide valuable clinical information. This…
Arterial pressure waveform; Collagen; Cranial rhythmic impulse; Fascia; Helix; Interstitial fluid flow; Mayer waves; Myofascia; Traube Hering - A++2016
Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study
James P Lugo, Zainulabedin M Saiyed, Nancy E LaneThis randomized, double-blind, placebo-controlled study evaluated the effects of undenatured type II collagen (UC-II) on symptoms of knee osteoarthritis. Over a 180-day period, 191 volunteers received either 40 mg of UC…
osteoarthritisKnee functionT regulatorycellUndenaturedtype II collagen - A++2015
Telocytes in regenerative medicine
Yihua Bei, Fei Wang, Changqing Yang, Junjie XiaoThis 2015 review article summarizes research on telocytes, a distinct type of cell found in the connective tissue of many organs. These cells form a complex 3D network and are thought to play a key role in guiding stem…
interstitial cells; progenitor cells; regeneration; regenerative medicine; stem cells; telocytes. - A++2015
Size Matters: Molecular Weight Specificity of Hyaluronan Effects in Cell Biology
Jaime M Cyphert, Carol S Trempus, Stavros GarantziotisThis narrative review summarizes current knowledge about hyaluronan, a molecule whose biological effects are dependent on its size. Unlike many other molecules, hyaluronan's signaling properties are determined not by ch…
hyaluronanCell signalingmolecular size - A++2015
BioTensegrity Fascia and the fallacy of biomechanics, Part 2.
John SharkeyIn this conceptual article, the second in a series, the author introduces BioTensegrity as an alternative to classical biomechanics. He argues that traditional models of animal and human movement, which date back to the…
biotensegrityBiomechanics - A++2015
BioTensegrity Fascia and the fallacy of biomechanics. Part 1
John SharkeyThis conceptual article introduces Biotensegrity as an emerging model for understanding human anatomy. It challenges traditional biomechanics by viewing the body as a continuous tensional network in which fascia plays a…
biotensegrityBiomechanics - A++2015
Glycine improves biochemical and biomechanical properties following inflammation of the achilles tendon
Cristiano Pedrozo Vieira, Letícia Prado De Oliveira, Flávia Da Ré Guerra, Marcos Dos Santos De Almeida, Maria Cristina…This animal study investigated the effect of the amino acid glycine on inflamed Achilles tendons in rats. Researchers induced inflammation and then fed one group of rats a diet supplemented with 5% glycine. After 22 day…
achilles tendon; extracellular matrix; glycine; inflammatory process; tendinopathy. - A++2015
Influence of different intensities of vibration on proliferation and differentiation of human periodontal ligament stem cells
Chunxiang Zhang, Yanqin Lu, Linkun Zhang, Yang Liu, Yi Zhou, Yangxi Chen, Haiyang YuIn this laboratory study, researchers investigated how low-magnitude, high-frequency vibration affects stem cells from the human periodontal ligament, the tissue that holds teeth in the jaw. The results suggest that vib…
Proliferationmechanical vibrationperiodontal ligament stem cellsosteogenesismagnitude - A++2015
Meralgia paresthetica caused by entrapment of the lateral femoral subcutaneous nerve at the fascia lata of the thigh: a case report and literature review
Yasuyuki Omichi, Ichiro Tonogai, Shinsuke Kaji, Teruaki Sangawa, Koichi SairyoThis case report and literature review describe an unusual presentation of meralgia paresthetica, a condition causing numbness and pain in the outer thigh. While the condition typically involves nerve entrapment at the…
nerve entrapment - A++2015
Neurovisceral phenotypes in the expression of psychiatric symptoms
Jessica A Eccles, Andrew P Owens, Christopher J Mathias, Satoshi Umeda, Hugo D CritchleyThis narrative review explores the idea that vulnerability to anxiety may be rooted in inherent physical differences in how the body is regulated. The authors focus on conditions like joint hypermobility, Postural Tachy…
joint hypermobilityAnxietypostural tachycardia syndromevasovagal syncopepsychiatry - A++2015
The Effects of Vibration and Muscle Fatigue on Trunk Sensorimotor Control in Low Back Pain Patients
Jean-Alexandre Boucher, Jacques Abboud, François Nougarou, Martin C Normand, Martin DescarreauxThis study compared trunk muscle control between people with chronic low back pain (cLBP) and healthy individuals. Researchers found that the cLBP group was less accurate at reproducing a specific amount of force with t…
fascialow back painmuscle fatiguevibration - A++2015
Effects of plant sterols derived from Aloe vera gel on human dermal fibroblasts in vitro and on skin condition in Japanese women
Miyuki Tanaka, Eriko Misawa, Koji Yamauchi, Fumiaki Abe, Chiaki IshizakiThis study investigated how plant sterols from Aloe vera gel affect the skin, using both laboratory tests on human skin cells (fibroblasts) and a clinical trial with women. In the lab, these sterols were found to stimul…
oral supplementationaloe sterol; collagen; wrinkle