Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2017
Shielding of the geomagnetic field reduces hydrogen peroxide production in human neuroblastoma cell and inhibits the activity of CuZn superoxide dismutase
Hai-Tao Zhang, Zi-Jian Zhang, Wei-Chuan Mo, Ping-Dong Hu, Hai-Min Ding, Ying Liu, Qian Hua, Rong-Qiao HeThis study investigates how an extremely weak magnetic field, similar to conditions in outer space or shielded environments on Earth, affects human cells. Researchers found that shielding the natural geomagnetic field r…
hydrogen peroxide; hypomagnetic field; oxidative stress; reactive oxygen species; superoxide dismutase - A+++2017
Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation
Benoit Chassaing, Tom Van de Wiele, Jana De Bodt, Massimo Marzorati, Andrew T GewirtzThis study investigated how common food additives, specifically the emulsifiers polysorbate 80 (P80) and carboxymethylcellulose (CMC), affect the gut microbiota. Using a laboratory model of the human intestinal ecosyste…
INFLAMMATION; INTESTINAL MICROBIOLOGY - A+++2017
Vitamin C Status Correlates with Markers of Metabolic and Cognitive Health in 50-Year-Olds: Findings of the CHALICE Cohort Study
John F Pearson, Juliet M Pullar, Renee Wilson, Janet K Spittlehouse, Margreet C M Vissers, Paula M L Skidmore, Jinny Wi…This cohort study examined vitamin C status in 404 fifty-year-olds in New Zealand. Researchers measured the concentration of vitamin C in participants' blood plasma as well as their dietary intake. The results showed th…
ascorbate; cognition; HbA1c; insulin; glucose; hypovitaminosis C - A+++2017
Role of Magnesium in Vitamin D Activation and Function
Anne Marie Uwitonze, Mohammed S RazzaqueIn this scientific review, the authors discuss how magnesium and vitamin D work together in the body. Magnesium acts as a cofactor, meaning it helps activate the enzymes that metabolize vitamin D in the liver and kidney…
Vitamin D activationmagnesiumcalcidefiolcalcitriol - A+++2017
Resveratrol Treatment Normalizes the Endothelial Function and Blood Pressure in Ovariectomized Rats
Victor Fabricio, Jorge Camargo Oishi, Bruna Gabriele Biffe, Leandro Dias Gonçalves Ruffoni, Karina Ana da Silva, Keico…This animal study on rats investigated how resveratrol affects blood pressure and vascular function during estrogen deficiency, mimicking post-menopausal conditions. Researchers found that a lack of estrogen led to high…
blood pressureresveratrolPostmenopause - A+++2017
Activation of type 2 cannabinoid receptor (CB2R) by selective agonists regulates the deposition and remodelling of the extracellular matrix
Tao Guan, Guiyang Zhao, Honghui Duan, Yang Liu, Feng ZhaoThis in vitro study investigated how activating the type 2 cannabinoid receptor (CB2R) affects scar formation in eye connective tissue after surgery. Researchers found that human Tenon’s fibroblasts express these recept…
Matrix metalloproteinase 1 (MMP-1); Tenon’s fibroblasts; Transforming growth factor-β1; Type 2 cannabinoid receptor (CB2R); Wound healing - A+++2017
Electric Nutrition: The Surprising Health and Healing Benefits of Biological Grounding (Earthing)
Stephen T Sinatra, James L Oschman, Gaétan Chevalier, Drew SinatraThis narrative review summarizes research on grounding (earthing), which involves direct physical contact with the Earth's surface. The authors suggest that grounding may provide a form of "electric nutrition" with pote…
Grounding - A+++2017
The deep fascia and retinacula of the equine forelimb - structure and innervation
Aleksandra Skalec, Monika EgerbacherThis study investigated the deep fascia and its reinforcements (retinacula) in the equine forelimb using anatomical dissection and microscopic analysis. The researchers found that horse fascia is structurally similar to…
equine; fascia; forelimb; innervation; retinaculum; structure - A+++2017
Early versus Delayed Rehabilitation after Acute Muscle Injury
Monika L Bayer, Peter Magnusson, Michael KjaerThis research entry, titled "Early versus Delayed Rehabilitation after Acute Muscle Injury," is currently awaiting a detailed summary. The title suggests it explores the optimal timing for starting rehabilitation follow…
Rehabilitationmuscle injurymechanical loading in rehabilitation - A+++2017
Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes
Chia-Wei Cheng, Valentina Villani, Roberta Buono, Min Wei, Sanjeev Kumar, Omer H Yilmaz, Pinchas Cohen, Julie B Sneddon…This study, involving mice and human pancreatic cells, explores how cycles of a fasting-mimicking diet (FMD) may influence the pancreas's ability to produce insulin. Researchers found that the diet appears to activate g…
fasting; fasting-mimicking diet; inflammation; intermittent fasting; diabetes - A+++2017
Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease
Min Wei, Sebastian Brandhorst, Mahshid Shelehchi, Hamed Mirzaei, Chia Wei Cheng, Julia Budniak, Susan Groshen, Wendy J…This randomized controlled trial examined the effects of a fasting-mimicking diet (FMD) on risk factors for age-related diseases in 100 healthy participants. For five consecutive days each month over a three-month perio…
fasting; fasting-mimicking diet; inflammation; intermittent fasting; cancer; diabetes; cardiovascular disease - A+++2016
Fascial Manipulation® for chronic aspecific low back pain: a single blinded randomized controlledtrial.
Mirco Branchini, Francesca Lopopolo, Ernesto Andreoli, Ivano Loreti, Aurélie M Marchand, Antonio SteccoThis randomized controlled trial compared Fascial Manipulation® combined with standard physiotherapy to physiotherapy alone for patients with chronic non-specific low back pain. The group receiving Fascial Manipulation®…
hyaluronanBack PainFascial manipulation