Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2018
The laterality of the gallop gait in Thoroughbred racehorses
Paulette Cully, Brian Nielsen, Bryony Lancaster, Jessica Martin, Paul McGreevyThis observational study investigated whether Thoroughbred racehorses have a preferred leading leg when transitioning from a halt to a gallop in starting stalls. Analyzing over 2,000 horses, researchers found no overall…
asymmetryrace horses - A+++2018
Improvement of Functional Ankle Properties Following Supplementation with Specific Collagen Peptides in Athletes with Chronic Ankle Instability
Patrick Dressler, Dominic Gehring, Denise Zdzieblik, Steffen Oesser, Albert Gollhofer, Daniel KönigThis randomized, placebo-controlled study investigated the effect of specific collagen peptides on athletes with chronic ankle instability (CAI). Fifty athletes received either a daily collagen supplement or a placebo f…
collagennutritionAnkle sprainligaments - A+++2018
The kinetics of gut microbial community composition in patients with irritable bowel syndrome following fecal microbiota transplantation
Tarek Mazzawi, Gülen Arslan Lied, Dag André Sangnes, Magdy El-Salhy, Johannes R Hov, Odd Helge Gilja, Jan Gunnar Hatleb…This clinical study investigated how fecal microbiota transplantation (FMT) affects gut bacteria and symptoms in patients with irritable bowel syndrome (IBS). Thirteen patients received stool from healthy donors via gas…
irritable bowel syndromeIBSFecal microbiota transplantation - A+++2018
Structure and Distribution of an Unrecognized Interstitium in Human Tissues
Petros C Benias, Rebecca G Wells, Bridget Sackey-Aboagye, Heather Klavan, Jason Reidy, Darren Buonocore, Markus Miranda…Using a new imaging technique, researchers identified a previously unrecognized, fluid-filled structure within the body's connective tissues. This network of collagen bundles and fluid-filled spaces, which they term the…
interstitiuminterstitial spacesfascia fluid - A+++2018
Effects of Plantar Vibration on Bone and Deep Fascia in a Rat Hindlimb Unloading Model of Disuse
Yunfei Huang, Yubo Fan, Michele Salanova, Xiao Yang, Lianwen Sun, Dieter BlottnerThis animal study investigated how disuse affects deep fascia and bone, and whether vibration could counteract these effects. Researchers used a rat model where hindlimbs were unloaded for 21 days to simulate disuse, wh…
extracellular matrixcollagenBonedeep fasciaBiomechanics - A+++2018
Effect of Health-Promoting Agents on Exclusion-Zone Size
Abha Sharma, Colby Adams, Benjamin D Cashdollar, Zheng Li, Nam V Nguyen, Himasri Sai, Jiachun Shi, Gautham Velchuru, Ke…This experimental study investigated how various health-promoting agents affect the formation of "exclusion zone" (EZ) water, often referred to as the fourth phase of water. Researchers found that substances such as hol…
dose dependent; dose response; exclusion zone water; health-promoting agents; hydrophilic surface; nutraceuticals - A+++2018
Exclusion zone and heterogeneous water structure at ambient temperature
Seong G Hwang, Jun Ki Hong, Abha Sharma, Gerald H Pollack, Gun Woong BahngThis study investigates how water interacts with hydrophilic surfaces to form "exclusion zones" (EZ)—regions where water is more structured and dense than bulk water. Researchers found that water can form three-dimensio…
exclusion zone waterEZ waterstructured water - A+++2018
Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis
Jing LiThis commentary presents a meta-analysis of research on using vitamin C to treat sepsis. It builds upon two previous reviews by pooling their data for a combined statistical analysis. The aggregated results indicated a…
meta-analysisVitamin CAscorbic acidsepsisSevere sepsis - A+++2017
Proinflammatory Cytokines and Oxidative Stress Decrease the Transport of Dopamine Precursor Tyrosine in Human Fibroblasts
Ravi Vumma, Jessica Johansson, Nikolaos VenizelosThis laboratory study investigated how inflammation and oxidative stress affect the transport of the amino acid tyrosine in human fibroblasts, a type of connective tissue cell. Tyrosine is a crucial precursor for the ne…
Dopamine precursor; Human fibroblasts; Neuropsychiatric disorders; Oxidative stress; Proinflammatory cytokines; Tyrosine transport. - A+++2017
Resveratrol supplementation reduces pain experience by postmenopausal women
Rachel H X Wong, Hamish M Evans, Peter R C HoweThis randomized, double-blind, placebo-controlled study investigated whether resveratrol supplementation could reduce pain and improve well-being in postmenopausal women. Over 14 weeks, participants taking 75 mg of resv…
Resveratrolpolyphenolemenopause - A+++2017
Therapeutic effectiveness of instrument-assisted soft tissue mobilization for soft tissue injury: mechanisms and practical application
Jooyoung Kim, Dong Jun Sung, Joohyung LeeThis narrative review explores the mechanisms and practical use of Instrument-Assisted Soft Tissue Mobilization (IASTM) for treating soft tissue injuries. IASTM involves using specialized tools to apply mechanical press…
Injury; Instrument-assisted soft tissue mobilization; Pain; Range of motion; Soft tissue function. - A+++2017
Resveratrol regulates body weight in healthy and ovariectomized rats
Rupali Sharma, Neel Kamal Sharma, M ThungapathraThis animal study on rats investigated how the plant compound resveratrol affects body weight in both healthy subjects and those who had undergone ovariectomy, a model for menopause. The results suggest that resveratrol…
OVX; Ovariectomy; Resveratrol; Soya free diet