Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2019
Vitamin C: an essential “stress hormone” during sepsis
Paul E MarikThe body's stress response involves hormones like cortisol and catecholamines, but in most mammals, it also includes increased production of vitamin C. These substances work together to protect the body from damage duri…
Sepsis; vitamin C; HPA axis; stress response - A+++2019
Fermented Foods: Definitions and Characteristics, Impact on the Gut Microbiota and Effects on Gastrointestinal Health and Disease
Eirini Dimidi, Selina Rose Cox, Megan Rossi, Kevin WhelanThis narrative review examines how fermented foods such as kefir, kombucha, and sourdough bread affect gut health and the microbiota. The authors describe how the fermentation process creates bioactive compounds and pot…
fermented food; kefir; kimchi; kombucha; miso; natto; sauerkraut; sourdough; soy; tempeh - A+++2018
Sagittal plane fore hoof unevenness is associated with fore and hindlimb asymmetrical force vectors in the sagittal and frontal planes
Sarah Jane Hobbs, Sandra Nauwelaerts, Jonathan Sinclair, Hilary M Clayton, Willem BackUnevenness in a horse's fore hooves, defined by differences in the dorsal hoof wall angle, affects how force is distributed across both the fore and hindlimbs. This study of 34 riding horses found that hooves with a ste…
asymmetryriding horsesuneven feethoof angleforce - A+++2018
Improvement of Functional Ankle Properties Following Supplementation with Specific Collagen Peptides in Athletes with Chronic Ankle Instability
Patrick Dressler, Dominic Gehring, Denise Zdzieblik, Steffen Oesser, Albert Gollhofer, Daniel KönigThis randomized, placebo-controlled study investigated the effect of specific collagen peptides on athletes with chronic ankle instability (CAI). Fifty athletes received either a daily collagen supplement or a placebo f…
collagennutritionAnkle sprainligaments - A+++2018
Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis
Jing LiThis commentary presents a meta-analysis of research on using vitamin C to treat sepsis. It builds upon two previous reviews by pooling their data for a combined statistical analysis. The aggregated results indicated a…
meta-analysisVitamin CAscorbic acidsepsisSevere sepsis - A+++2018
Effects of local vibration therapy on various performance parameters: a narrative literature review
Darrin Germann, Amr El Bouse, Jordan Shnier, Nader Abdelkader, Mohsen KazemiThis narrative literature review examines how local muscle vibration (LMV) affects performance parameters such as strength, power, and range of motion. By applying vibrations directly to a specific muscle or tendon, LMV…
chiropractic; local muscle vibration; performance; vibration. - A+++2018
Depression and anxiety in patients with chronic heart failure
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Beatrice SacconiIn this review article, the authors discuss the connection between chronic heart failure (CHF), mental health, and diaphragm function. CHF is a serious, progressive condition often accompanied by depression and anxiety.…
anxiety • baroreceptors • chronic heart failure • diaphragm • depression • inflammatory cytokines • phrenic nerve • psychiatric disorders • rehabilitation • vagus nerve - A+++2018
Effects of Plantar Vibration on Bone and Deep Fascia in a Rat Hindlimb Unloading Model of Disuse
Yunfei Huang, Yubo Fan, Michele Salanova, Xiao Yang, Lianwen Sun, Dieter BlottnerThis animal study investigated how disuse affects deep fascia and bone, and whether vibration could counteract these effects. Researchers used a rat model where hindlimbs were unloaded for 21 days to simulate disuse, wh…
extracellular matrixcollagenBonedeep fasciaBiomechanics - A+++2018
Effect of Health-Promoting Agents on Exclusion-Zone Size
Abha Sharma, Colby Adams, Benjamin D Cashdollar, Zheng Li, Nam V Nguyen, Himasri Sai, Jiachun Shi, Gautham Velchuru, Ke…This experimental study investigated how various health-promoting agents affect the formation of "exclusion zone" (EZ) water, often referred to as the fourth phase of water. Researchers found that substances such as hol…
dose dependent; dose response; exclusion zone water; health-promoting agents; hydrophilic surface; nutraceuticals - A+++2018
Anatomical and Functional Relationships Between External Abdominal Oblique Muscle and Posterior Layer of Thoracolumbar Fascia
Chenglei Fan, Caterina Fede, Nathaly Gaudreault, Andrea Porzionato, Veronica Macchi, Raffaele de Caro, Carla SteccoThis study investigated the anatomical connection between the external abdominal oblique muscle (EO) and the thoracolumbar fascia (TLF) in the low back. Using both cadaveric dissection and CT scans, researchers found a…
external abdominal oblique muscle; fascia; lumbar; computed tomography - A+++2018
Low-Intensity Vibration Improves Muscle Healing in a Mouse Model of Laceration Injury
Thomas F Corbiere, Eileen M Weinheimer-Haus, Stefan Judex, Timothy J KohIn this animal study, researchers investigated if low-intensity vibration (LIV) could improve healing of lacerated calf muscles in mice. The mice were divided into groups that received daily vibration treatment and a co…
skeletal muscle injury; laceration; low-intensity vibration; muscle regeneration; fibrosis - A+++2018
Resveratrol: A Double-Edged Sword in Health Benefits
Bahare Salehi, Abhay Prakash Mishra, Manisha Nigam, Bilge Sener, Mehtap Kilic, Mehdi Sharifi-Rad, Patrick Valere Tsouh…This narrative review explores resveratrol, a natural polyphenol found in grape skins, red wine, and various plants. Research suggests that this compound possesses significant antioxidant, anti-inflammatory, and cardiop…
anticancer; antimicrobial; antioxidant; pharmacological activity; physiological effects; resveratrol.