Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2020
Diet as a Modulator of Intestinal Microbiota in Rheumatoid Arthritis
Eduardo Dourado, Margarida Ferro, Catarina Sousa Guerreiro, João Eurico FonsecaThis narrative review explores how dietary patterns can influence the gut microbiota in individuals with rheumatoid arthritis (RA). Research indicates that RA patients often exhibit significant differences in their inte…
Mediterranean diet; gut microbiota; probiotics; rheumatoid arthritis - A+++2020
Cannabinoids in Medicine: Cancer, Immunity, and Microbial Diseases
Paweł Śledziński, Agnieszka Nowak-Terpiłowska, Joanna ZeylandThis narrative review explores how cannabinoids, including those from plants and those produced naturally by the body, influence health through the endocannabinoid system. The authors describe how these compounds intera…
cancer medicine; cannabinoid receptors; cannabinoids; immune medicine - A+++2020
Low-frequency mechanical vibration induces apoptosis of A431 epidermoid carcinoma cells
Wresti L Anggayasti, Chikahiro Imashiro, Taiki Kuribara, Kiichiro Totani, Kenjiro TakemuraResearchers are exploring mechanical vibration as a potential cancer therapy that avoids harming healthy cells. In this lab study, a brief, low-frequency vibration was applied to a line of human skin cancer cells (A431)…
apoptosismechanical vibrationcancer cell modelglucose metabolismhigh-mobility group box 1 - A+++2020
Perspective: Vitamin D deficiency and COVID-19 severity –plausibly linked by latitude, ethnicity, impacts on cytokines,ACE2 and thrombosis
J M Rhodes, S Subramanian, E Laird, G Griffin, R A KennyThis narrative review explores the potential link between vitamin D deficiency and the severity of COVID-19. The authors observed that countries at higher latitudes, with less sun exposure, had higher COVID-19 mortality…
cytokineCOVID-19vitamin D - A+++2020
The feasibility and impact of instrument-assisted manual therapy (IAMT) for the lower back on the structural and functional properties of the lumbar area in female soccer players: a randomised, placebo-controlled pilot study design
Patrick Weber, Christine Graf, Werner Klingler, Nadine Weber, Robert SchleipThis is a protocol for a pilot study designed to investigate the feasibility and impact of instrument-assisted manual therapy (IAMT) for the lower back in female soccer players. The researchers plan to compare IAMT with…
Thoracolumbar fasciaMyofascialultrasound.AthletesInstrument-assisted - A+++2020
Flavonoids and Other Polyphenols Act as Epigenetic Modifiers in Breast Cancer
Priyanga Selvakumar, Aja Badgeley, Paige Murphy, Hina Anwar, Urvashi Sharma, Katharine Lawrence, Ashakumary Lakshmikutt…This narrative review explores how dietary flavonoids and other polyphenols may influence breast cancer through epigenetic mechanisms. Research suggests that compounds found in green tea, soy, and berries can affect gen…
Epigenetics; breast cancer; chromatin modification; flavonoids; methylation - A+++2020
An anatomical comparison of the fasciae of the thigh: A macroscopic, microscopic and ultrasound imaging study
Carmelo Pirri, Caterina Fede, Lucia Petrelli, Diego Guidolin, Chenglei Fan, Raffaele De Caro, Carla SteccoResearchers compared the thigh's fascial layers using three methods: dissection of cadavers, microscopic analysis, and ultrasound imaging of living volunteers. They identified distinct layers, including a superficial fa…
fascia lataImagingThicknessmusculo-skeletal ultrasoundsuperficial fascia - A+++2020
Endocannabinoids release after Osteopathic Manipulative Treatment. A brief review
Andrea Buscemi, Simona Martino, Santi Scirè Campisi, Alessandro Rapisarda, Marinella CocoThis brief review examines how Osteopathic Manipulative Treatment (OMT) may influence the body's endocannabinoid system, which is crucial for pain regulation and emotional well-being. By analyzing existing research, the…
chronic pain; endocannabinoids; hypothalamic-pituitary-adrenal axis; osteopathic manipulative treatment - A+++2020
Mini-Review on the Roles of Vitamin C, Vitamin D, and Selenium in the Immune System against COVID-19
Minkyung Bae, Hyeyoung KimThis mini-review discusses how vitamin C, vitamin D, and selenium may affect the immune system in relation to COVID-19. Research suggests that deficiencies in these micronutrients are common in patients with acute respi…
COVID-19; infectious disease; selenium; virus; vitamin C; vitamin D - A+++2020
Collagen supplementation for skin health: A mechanistic systematic review
Meisam Barati, Masoumeh Jabbari, Roya Navekar, Fariba Farahmand, Reihaneh Zeinalian, Ammar Salehi-Sahlabadi, Nasrin Abb…This systematic review evaluates the impact of collagen supplementation on skin health and aging parameters. By analyzing ten clinical trials, researchers found that oral intake of both intact and hydrolyzed collagen co…
M2-like macrophage; collagen; collagen hydrolysate; oral tolerance; regulatory T cell; skin health. - A+++2020
The Five Diaphragms in Osteopathic Manipulative Medicine: Myofascial Relationships, Part 2
Bruno BordoniThis conceptual review article continues an examination of the "five diaphragms" concept within osteopathic manipulative medicine. The paper focuses on the myofascial connections along the front and sides of the body, e…
fasciaMyofascialOsteopathicdiaphragmphysiotherapy - A+++2020
The Five Diaphragms in Osteopathic Manipulative Medicine: Myofascial Relationships, Part 1
Bruno BordoniThis review article outlines the osteopathic concept of the body's "five diaphragms": the tentorium cerebelli, tongue, thoracic outlet, respiratory diaphragm, and pelvic floor. According to the osteopathic respiratory-c…
fasciaMyofascialOsteopathicdiaphragmphysiotherapy