The key to left-right asymmetry

Clifford J Tabin

EmbryologySignaling

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Key takeaways

01Cilia are essential components for breaking initial biological symmetry
02Asymmetric signaling cascades guide the positioning of internal organs
03

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A midline barrier helps maintain the established left-right asymmetry

04Reaction-diffusion mechanisms likely play a key role in the process

The establishment of left-right asymmetry in vertebrates relies on cilia, signaling cascades, and reaction-diffusion mechanisms.

Abstract

Establishment of left-right asymmetry in vertebrates involves cilia as essential components in the breaking of symmetry, an asymmetric signaling cascade, and a midline barrier that helps to maintain asymmetry. A new study suggests that a reaction-diffusion mechanism also plays a key role.

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Cite this study

APA: Clifford J Tabin (2006). The key to left-right asymmetry.
MLA: Clifford J Tabin. "The key to left-right asymmetry." 2006.
Chicago: Clifford J Tabin. 2006. "The key to left-right asymmetry."