Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesUltra-processed foods and food additives in gut health and disease
This narrative review examines the link between ultra-processed foods (UPFs), food additives, and gastrointestinal health. Research suggests that diets high in UPFs are associated with an increased risk of inflammatory…
B-Group Vitamins as Potential Prebiotic Candidates: Their Effects on the Human Gut Microbiome
This narrative review explores whether B-group vitamins can act as prebiotics by promoting the growth of beneficial gut bacteria. The authors discuss how B-vitamins that are not absorbed in the small intestine can reach…
Therapeutic applications of gut microbes in cardiometabolic diseases: current state and perspectives
This narrative review explores the relationship between gut microbiota and cardiometabolic diseases (CMD), such as hypertension, obesity, and type 2 diabetes. The authors describe how gut microbes and their metabolites…
Gut-Brain Interactions and Their Impact on Astrocytes in the Context of Multiple Sclerosis and Beyond
This narrative review explores how the interaction between the gut microbiome and the brain influences the progression of multiple sclerosis (MS). The researchers describe how imbalances in gut bacteria can lead to bact…
The Combined Effect of Static Stretching and Foam Rolling With or Without Vibration on the Range of Motion, Muscle Performance, and Tissue Hardness of the Knee Extensor
This study investigated how the order of static stretching (SS) and foam rolling (FR), with or without vibration, affects range of motion, muscle strength, and tissue hardness in the quadriceps. The results showed that…
Functional organization of extracellular hyaluronan, CD44 and RHAMM
In this comprehensive review, the authors explore how hyaluronan (HA) and its receptors, CD44 and RHAMM, organize the space immediately surrounding cells. In healthy tissue, these components maintain a stable environmen…
Pain quality patterns in delayed onset muscle soreness of the lower back suggest sensitization of fascia rather than muscle aferents: a secondary analysis study
This study investigated whether delayed onset muscle soreness (DOMS) in the lower back originates from the muscles or the surrounding connective tissue (fascia). Researchers had participants perform fatiguing back exerc…
Fasting-mimicking diet synergizes with ferroptosis against quiescent, chemotherapy-resistant cells
This study investigates how a fasting-mimicking diet (FMD) affects colorectal cancer cells, particularly those resistant to chemotherapy. Researchers found that while fasting slows tumor growth, it can also cause cancer…
The Cognitive and Emotional Aspect in Fibromyalgia: The Importance of the Orofacial Sphere
This narrative review explores the link between fibromyalgia and issues in the orofacial region, such as temporomandibular joint (TMJ) disorders and periodontitis. The authors suggest that oral inflammation may contribu…
A New Player in the Mechanobiology of Deep Fascia: Yes-Associated Protein (YAP)
This study investigated the role of Yes-associated protein (YAP) in the mechanobiology of deep fascia, specifically the thoracolumbar fascia. Researchers analyzed tissue samples from patients and found that YAP acts as…
What's old is new again: The anatomical studies of Franklin P. Mall and the fascial-interstitial spaces
Franklin Mall was a pioneering anatomist at the turn of the 19th century whose work is being rediscovered in light of modern fascia research. He studied under Wilhelm His and Carl Ludwig, learning to integrate anatomy w…
Fasting and fasting mimicking diets in cancer prevention and therapy
This review explores how cycles of fasting-mimicking diets (FMD) may aid in cancer prevention and therapy. FMDs are designed to be safer and more manageable than water-only fasting while potentially protecting healthy c…