Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesTriggerband technique
The Triggerband Technique is a manual therapy approach for treating musculoskeletal pain and dysfunction. It is based on the idea that distorted or injured fascial bands are the cause of many types of physical discomfor…
Anal-sphincter disruption during vaginal delivery
Researchers investigated how often hidden (occult) damage to the anal sphincter occurs during vaginal childbirth and how it affects bowel control. They studied over 200 women before and after delivery using ultrasound a…
Angiogenic oligosaccharides of hyaluronan enhance the production of collagens by endothelial cells
This study investigated how small fragments of hyaluronan (HA) affect collagen production during the formation of new blood vessels, a process called angiogenesis. Researchers observed that applying these HA fragments t…
Immunological evidence for the accumulation of lipoprotein(a) in the atherosclerotic lesion of the hypoascorbemic guinea pig
This animal study investigated the link between vitamin C, a specific cholesterol particle called Lipoprotein(a) or Lp(a), and atherosclerosis. Researchers found that guinea pigs, which like humans cannot produce their…
Endothelial Growth Factors and Extracellular Matrix Regulate Dna Synthesis Through Modulation of Cell and Nuclear Expansion
This study investigated how the extracellular matrix (ECM) and growth factors work together to regulate the growth of capillary endothelial cells, which line blood vessels. Researchers found that these cells needed both…
Structure and Properties of Ground Substances
This 1984 review outlines the structure of the body's 'ground substance,' the matrix found both within and between our cells. The author describes how this substance is composed of different biopolymers in the extracell…
THE INFLUENCE OF MECHANICAL FORCES ON THE GLYCOSAMINOGLYCAN CONTENT OF THE RABBIT FLEXOR DIGITORUM PROFUNDUS TENDON
In this animal study on rabbits, researchers surgically altered the mechanical forces on a deep finger flexor tendon to observe how the tissue adapted. They analyzed how the content of glycosaminoglycans (GAGs)—molecule…
Supplemental ascorbate in the supportive treatment of cancer: Reevaluation of prolongation of survival times in terminal human cancer
This study compared the survival times of 100 terminal cancer patients who received supplemental ascorbate (vitamin C) with 1000 matched control patients who did not. The ascorbate-treated group was found to have a mean…
Ascorbic acid status in idiopathic hemochromatosis
This study investigated Vitamin C (ascorbic acid) levels in patients with idiopathic hemochromatosis, a condition characterized by excessive iron accumulation. The results showed that untreated patients had significantl…
SYNTHESIS AND SOME MAJOR FUNCTIONS OF VITAMIN C IN ANIMALS
Vitamin C, or ascorbic acid, is essential for most living things, but some animals, including humans, cannot produce it themselves. Historically, determining an animal's ability to synthesize Vitamin C required feeding…
Orthomolecular psychiatry. Varying the concentrations of substances normally present in the human body may control mental disease
In this 1968 theoretical paper, the concept of orthomolecular psychiatry is introduced. The author proposes that mental illness may result from imbalances in the concentrations of substances normally present in the brai…