Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesTensegrity and mechanoregulation: from skeleton to cytoskeleton
This review article explores how mechanical forces are transmitted from the whole body down to individual cells. The authors propose that a design principle called "tensegrity," which uses continuous tension and local c…
Oral Administration of 14C Labeled Gelatin Hydrolysate Leads to an Accumulation of Radioactivity in Cartilage of Mice (C57/BL)
In this animal study, researchers investigated how gelatin hydrolysate is absorbed and distributed in the bodies of mice. Using a radioactive label, they tracked the gelatin after it was administered orally. The results…
The Architecture of Life
As this is a title-only entry, the full text has not yet been reviewed. The title, "The Architecture of Life," suggests a focus on the structural principles governing biological systems, possibly involving concepts like…
Thyroid hormone-induced upregulation of Na channels and Na-K pumps: implications for contractility
In this animal study, researchers investigated how thyroid hormone affects muscle endurance in rats. They treated rats with the hormone T3, which increased the concentration of both sodium (Na+) channels and sodium-pota…
Tensegrity: The Architectural Basis of Cellular Mechanotransduction
This 1997 review article proposes a model for how cells sense and respond to physical forces, a process called mechanotransduction. The author suggests that cells are built using 'tensegrity' architecture, a system of b…
Biophoton emission of the human body
Researchers measured "ultraweak" photon emissions, or biophotons, from the human body using a sensitive light detector. The study, involving about 200 individuals, found that these emissions are not random. They appear…
Functional morphology of serially linked skeletal muscle fibers
Skeletal muscle fibers don't always run the full length of a muscle; they often link together in series. This study describes two main ways these connections occur: end-to-end via connective tissue plates, or by overlap…
Mechanical Loading and TGF-b Regulate Proteoglycan Synthesis in Tendon
Tendons can develop cartilage-like properties in areas subjected to compressive loading. In this study on fetal bovine tendon tissue, researchers investigated how mechanical compression affects the cells. They found tha…
Effects of continuous and Intermittent forces on human fibroblasts in vitro
This in vitro study investigated how human connective tissue cells (fibroblasts) respond to different types of mechanical force. Researchers grew fibroblasts on flexible membranes and subjected them to either continuous…
Selective regulation of myofiber differentiation by energy status during postnatal development
In this animal study, researchers investigated how energy intake and environmental temperature affect muscle development in young pigs. The pigs were divided into groups that received either a high or low energy intake…
Clinical consequences of anal sphincter rupture during vaginal delivery
This study investigated the incidence and consequences of anal sphincter tears during childbirth. Researchers followed 51 women with a diagnosed tear and 31 women without one for six months after delivery. They found th…
Glutathione-Ascorbic Acid Antioxidant System in Animals
This 1994 publication by Alton Meister discusses the biochemical interaction between glutathione and ascorbic acid (Vitamin C) within animal antioxidant systems. As the source material is limited to the title, the summa…