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The Fascia Guide
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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 1,081–1,092 of 1,127 studies · page 91/94With summary
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  1. A++
    2003

    Stimulation of type II collagen biosynthesis and secretion in bovine chondrocytes cultured with degraded collagen

    Steffen Oesser, Jürgen Seifert

    This laboratory study investigated how degraded collagen affects cartilage cells. Researchers cultured chondrocytes from cows and added collagen hydrolysate (small collagen fragments) to their environment. They found th…

    Collagen hydrolysate; Collagen secretion; Chondrocyte metabolism; Type II collagen; Cell culture (Bovine)
  2. A
    2003

    The myofibroblast in wound healing and fibrocontractive diseases

    G Gabbiani

    During wound healing, cells called fibroblasts can transform into a more specialized type called myofibroblasts. These myofibroblasts have contractile properties, much like muscle cells, which help to pull the edges of…

    inflammationα-smooth muscle actinstress fibresTGF-β1 fibronectintension
  3. 1A+
    2003

    The Common Compensatory Pattern: Its Origin and Relationship to the Postural Model

    Ross E Pope

    As only the title of this paper is available, we cannot summarize its contents in detail. The title suggests the article explores a concept known as the 'Common Compensatory Pattern'. The author likely discusses the ori…

    fasciaCompensatory patternposture
  4. A
    2003

    Vitamin C, respiratory infections and the immune system

    Harri Hemilä

    This 2003 publication by Harri Hemilä explores the relationship between Vitamin C, respiratory infections, and immune system function. As only the title is available, specific conclusions regarding the study's exact res…

    Vitamin CAscorbic acid
  5. A+
    2003

    Stress shielding of patellar tendon: effect on small-diameter collagen fibrils in a rabbit model

    Tokifumi Majima, Kazunori Yasuda, Takamasa Tsuchida, Kunio Tanaka, Kiyoshi Miyakawa, Akio Minami, Kozaburo Hayashi

    In this animal study, researchers investigated the effects of mechanical unloading, or "stress shielding," on the patellar tendon in rabbits. The scientists completely released the tendon from its normal stress for thre…

    Stress shielding · Patellar tendon · Collagen fibril diameter · Ultrastructure
  6. A++
    2003

    Prevalence of urinary and fecal incontinence and symptoms of genital prolapse in women

    Eva Uustal Fornell, Gun Wingren, Preben Kjølhede

    This questionnaire study investigated the links between urinary incontinence, fecal incontinence, and symptoms of genital prolapse in Swedish women. The researchers found that these three conditions often occur together…

    fecal incontinencegenital prolapseepidemiologydetrusor instabilityfemale urinary incontinence
  7. A
    2003

    New and active role of the interstitium in control of interstitial fluid pressure: potential therapeutic consequences

    H Wiig, K Rubin, R K Reed

    This review challenges the traditional view of the interstitium as merely a passive fluid reservoir. The researchers present data suggesting that connective tissue cells and the extracellular matrix actively regulate in…

    inflammationextracellular matrixInterstitial fluid volumeintegrins edema
  8. A
    2003

    Biophoton emission of human body

    S Cohen, F A Popp

    Researchers measured the very faint light, or "biophotons," emitted by the human body using a special photon detector. They found that these emissions are not random, but seem to reflect the body's left-right symmetry a…

    BiophotonBiological regulationBiological rhythmsHuman body measurmentLeft right symmetry
  9. A
    2003

    Mechanobiology and diseases of mechanotransduction

    Donald E Ingber

    This 2003 article argues that medicine often overlooks the physical and mechanical aspects of disease, focusing instead on genetics. The author reviews how physical forces and the extracellular matrix are vital for norm…

    extracellular matrixcytoskeletonmechanotransductionIntegrinstissue engineering
  10. C
    2002

    Age-related Changes in the Collagen Network and Toughness of Bone

    X Wang, X Shen, X Li, C Mauli Agrawal

    This study investigated how the collagen network in bone tissue changes with age and how this affects bone toughness. Researchers analyzed 30 femurs from human cadavers, with donors ranging from 19 to 89 years of age. T…

    collagenAgingBoneToughnessDenaturation
  11. A
    2002

    Relationship of Acupuncture Points and Meridians to Connective Tissue Planes

    Helene M Langevin, Jason A Yandow

    Researchers investigated the hypothesis that the network of acupuncture points and meridians could represent the body's network of interstitial connective tissue. By mapping points in anatomical cross-sections of a huma…

    acupuncture; meridians; connective tissue; anatomy; fascia; signal transduction
  12. A
    2002

    Adhesive capsulitis: role of MR imaging in differential diagnosis

    David Connell, Ravi Padmanabhan, Rachelle Buchbinder

    This study investigated whether magnetic resonance imaging (MRI) can identify the changes typical of adhesive capsulitis (frozen shoulder). Researchers compared MRI scans from 24 patients with clinical evidence of froze…

    frozen shoulderAdhesive capsulitisMR imagingArthroscopy