Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies

2,806

studies

602

top-graded

2,783

with plain-language summary

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Showing 985–996 of 1,127 studies · page 83/94With summary

A
2008
Anti-angiogenic effect of high doses of ascorbic acid
Nina A Mikirova, Thomas E Ichim, Neil H Riordan
This laboratory study investigated how high doses of ascorbic acid (vitamin C) affect the formation of new blood vessels, a process called angiogenesis. Researchers exposed several types of human endothelial cells, incl…
AngiogenesisVitamin CAscorbic acid
A
2008
Fibronectin Unfolding Revisited: Modeling Cell Traction- Mediated Unfolding of the Tenth Type-III Repeat
Elaine P S Gee, Donald E Ingber, Collin M Stultz
Cells build the extracellular matrix by pulling on the protein fibronectin, causing it to assemble into fibrils. This study used computer simulations to investigate how this process works at a molecular level. Researche…
fasciaFibronectincell tractionintegrinfibrillogenesis
A
2008
Differential effects of hyaluronan and its fragments on fibroblasts: Relation to wound healing
Maha David-Raoudi, Frederic Tranchepain, Brigitte Deschrevel, Jean-Claude Vincent, Patrick Bogdanowicz, Karim Boumedien…
This lab study investigated how hyaluronan (HA) of different molecular sizes affects human fibroblast cells, which are key to wound healing. Researchers exposed fibroblasts to native HA and two smaller fragments. All th…
hyaluronanfasciawound healingextracellular matrixfibrosis
B
2008
Hyaluronan (HA) Deposition Precedes and Promotes Leukocyte Recruitment in Intestinal Inflammation
Kessler S, Rho H, West G, Fiocchi C, Drazba J, de la Motte C
Hyaluronan (HA) accumulation is common in inflammatory bowel disease (IBD), but whether it is a cause or an effect has been unclear. In this study using a mouse model and human tissue, researchers found that HA builds u…
inflammationcolitisinflammatory bowel diseaseintestineendothelium
A
2008
Simple geometry in complex organisms
Graham Scarr
This theoretical paper explores how simple geometric principles can explain the formation of complex biological structures. The author revisits ancient ideas about fundamental shapes, connecting them to modern concepts…
TensegrityCrystallographyhelixicosahedronnatural law
A
2008
Vitamin C Deficiency in a University Teaching Hospital
Runye Gan, Shaun Eintracht, L John Hoffer
This study investigated vitamin C levels in patients at a Canadian teaching hospital. Researchers found that 60% of patients had low levels and 19% were deficient, a much higher rate than in a healthy reference group. F…
supplementationAscorbic acidVitamins.scurvy
A+++
2008
Correlation Between Fluctuations in Human Ultra-weak Photon Emission and EEG Alpha Rhythm
Roeland Van Wijk, Saskia Bosman, John Ackerman, Eduard P A Van Wijk
This study investigated the relationship between ultra-weak photon emission (UPE) from the skin and brain activity measured via EEG. Researchers recorded light emission from the hand while simultaneously monitoring brai…
biophotonsUltra-weak photon emissionHumanAlpha suppressionEEG
A
2008
Dorsal horn neurons having input from low back structures in rats
T Taguchi, U Hoheisel, S Mense
In this animal study, researchers in rats investigated how spinal cord nerve cells (dorsal horn neurons) process signals from the low back. They found that these neurons often receive input from several different tissue…
fascialow back painmultifidus muscledorsal horn neuronsnerve growth factor (NGF)
1A+
2008
Expression of the endocannabinoid system in fibroblasts and myofascial tissues
J M McPartland
This narrative review investigates the endocannabinoid (eCB) system, a network in the body similar to the endorphin system that helps regulate pain and inflammation. Using a bioinformatics approach to analyze existing d…
Cannabinoids; Endocannabinoids; Ajulemic acid; Osteopathic medicine; Chiropractic; Myofascial release; Fibromyalgia; Myofascial trigger points; Biodynamics
A
2008
Tensegrity and Mechanotransduction
D E Ingber
This article summarizes a lecture on how mechanical forces influence biological processes at the cellular level. The author describes mechanotransduction, the process by which cells convert physical forces into biochemi…
fasciaTensegritycytoskeletonmechanotransductionIntegrins
A
2008
Diagnosis and management of adhesive capsulitis
Robert C Manske, Daniel Prohaska
This 2008 review discusses adhesive capsulitis, also known as frozen shoulder, a disabling musculoskeletal condition. The authors cover the diagnosis and management of the condition, which can cause significant morbidit…
SurgeryAdhesive capsulitisShoulder pain
A
2008
Tensegrity-Based Mechanosensing from Macro to Micro
Donald E Ingber
This review article, based on a lecture, explores how cells convert mechanical signals into biochemical responses. The author proposes that the body uses "tensegrity" (tensional integrity) principles, where interconnect…
fasciaextracellular matrixTensegritycytoskeletonmechanotransduction