Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesSensory Innervation of the Nonspecialized Connective Tissues in the Low Back of the Rat
In this animal study, researchers investigated the sensory nerves in the nonspecialized connective tissue of the rat low back, an area where knowledge is limited. Using 3D reconstruction and dye-labeling techniques, the…
ExtracellularMatrix Degradation and Remodeling in Development and Disease
In this review, the authors describe the extracellular matrix (ECM) as a dynamic structure that is constantly being remodeled. This process of breakdown and rebuilding is essential for normal bodily functions like tissu…
The effect of molecular weight on hyaluronan’s cartilage boundary lubricating ability e alone and in combination with proteoglycan 4
This study investigated the lubricating ability of hyaluronan (HA) in articular cartilage, focusing on how its molecular weight affects function. Researchers found that higher molecular weight hyaluronan was more effect…
The Alkaline Diet: Is There Evidence That an Alkaline pH Diet Benefits Health
This 2011 review examined the published medical literature to evaluate the health benefits of an alkaline diet. The author looked at studies on the body's pH and its connection to bone health, muscle function, back pain…
Diet-induced metabolic acidosis
The typical Western diet, high in animal products and low in fruits and vegetables, can lead to a state of chronic, low-grade metabolic acidosis. This means the body becomes slightly more acidic, a situation that can wo…
Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44
This study investigated the mechanisms behind severe lung fibrosis, a condition where excessive connective tissue builds up in the lungs. Using a mouse model, researchers found that fibroblasts, a type of connective tis…
Fascia and the mechanism of acupuncture
This theoretical paper re-evaluates the mechanisms of acupuncture. The authors propose that fascia, the body's connective tissue network, is the structure that explains how acupuncture works. They argue for this model b…
Correlations Between Fasciology and Yin Yang Doctrine
This theoretical paper explores correlations between "fasciology," a model based on 3D reconstruction of connective tissue, and the traditional Chinese doctrine of yin and yang. According to fasciology, the body can be…
Fascia redefined: anatomical features and technical relevance in fascial flap surgery
Fascia has traditionally been seen as a passive wrapping, but this review redefines it as a dynamic tissue with its own complex blood supply and innervation. The authors detail the specific characteristics of different…
Pandiculation: Nature’s way of maintaining the functional integrity of the myofascial system?
This paper explores the hypothesis that pandiculation—the involuntary stretching and yawning most animals do upon waking—serves a key role for the locomotor system. Beyond preparing the nervous system for wakefulness, t…
Fibroblast cytoskeletal remodeling contributes to connective tissue tension
The mechanical properties of connective tissue, such as its elasticity and resistance, have traditionally been attributed to its non-cellular matrix. This study investigated the role of fibroblasts, the cells residing w…
Change in knee osteoarthritis cartilage detected by delayed gadolinium enhanced magnetic resonance imaging following treatment with collagen hydrolysate: a pilot randomized controlled trial
This pilot randomized controlled trial investigated if collagen hydrolysate supplements could affect knee cartilage in people with mild osteoarthritis. Using a specialized MRI technique (dGEMRIC), researchers tracked ch…