Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesCell-to-cell signaling through light: just a ghost of chance?
This paper examines the physical feasibility of cell-to-cell communication via weak light signals, often referred to as biophotons. The researchers analyze whether electromagnetic signaling is possible when considering…
Human skeletal muscle ascorbate is highly responsive to changes in vitamin C intake and plasma concentrations
This study investigated how vitamin C intake affects its concentration in human skeletal muscle. Researchers gave 36 men either half a kiwifruit or two kiwifruits daily for six weeks, as kiwifruit is a rich source of vi…
Exercise training initiated in late middle age attenuates cardiac fibrosis and advanced glycation end-product accumulation in senescent rats
This animal study investigated if exercise started later in life could still benefit the aging heart. Researchers had late middle-aged rats begin treadmill training and continue into old age, comparing them to sedentary…
Primo Vascular System: Past, Present, and Future
As only the title of this article was available, this summary is necessarily limited. The title, "Primo Vascular System: Past, Present, and Future," suggests this is a review article. It likely covers the history of the…
Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects: a possible link between obesity and local tissue inflammation?
Researchers compared lymphatic drainage from abdominal fat tissue in lean and obese men. They measured drainage before and after the men consumed a glucose drink, which mimics the body's response to a meal. In lean men,…
The effect of acute exercise on collagen turnover in human tendons: influence of prior immobilization period
Researchers investigated how a period of immobility affects the Achilles tendon's response to exercise. In this study, eight healthy men had one leg immobilized for two weeks while the other was used normally. Afterward…
TGF-β: Guardian of T Cell Function
In this review article, the authors discuss the role of the cytokine TGF-β (transforming growth factor-beta) in the immune system. TGF-β is critical for regulating T cells, a type of white blood cell central to the adap…
Plantar fascia anatomy and its relationship with Achilles tendon and paratenon
This study investigated the detailed anatomy of the plantar fascia and its connection to the Achilles tendon. Dissections of human cadavers revealed that the fascia is more closely linked to the paratenon (the tendon's…
Sensory findings after stimulation of the thoracolumbar fascia with hypertonic saline suggest its contribution to low back pain
This experimental study investigated the role of the thoracolumbar fascia as a potential source of low back pain. Researchers injected a pain-inducing saline solution into the fascia, back muscles, and subcutaneous tiss…
Understanding mechanotransduction and biotensegrity from an adaptation perspective
This article, for which only the title is available, appears to be a conceptual exploration of mechanotransduction and biotensegrity. Mechanotransduction is the process by which cells sense and respond to mechanical for…
Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin-C deficient mice
This animal study investigated how Vitamin C (ascorbate) supplementation affects cancer growth in mice that, like humans, cannot produce their own. Researchers injected melanoma or breast cancer cells into two groups of…
Vitamin C in Disease Prevention and Cure: An Overview
This narrative review provides an overview of Vitamin C's many roles in the body. It is essential for developing and maintaining connective tissues, and plays a key part in bone formation, wound healing, and gum health.…