Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesEvidence for the existence of nociceptors in rat thoracolumbar fascia
This animal study on rats investigated the presence of pain-sensing nerve fibers (nociceptors) in the thoracolumbar fascia. Researchers compared normal fascia with tissue in which they had induced inflammation. The resu…
Essential Experimental Methods for Identifying Bonghan Systems as a Basis for Korean Medicine: Focusing on Visual Materials from Original Papers and Modern Outcomes
This narrative review examines methods for identifying the so-called Bonghan system, also known as the primo vascular system (PVS). This system was originally proposed in the 1960s as the anatomical basis for acupunctur…
The content and size of hyaluronan in biological fluids and tissues
Hyaluronan is a simple sugar polymer found throughout the body's tissues and fluids. It is typically produced as a very large, high-molecular-mass molecule. This narrative review notes that during processes like inflamm…
Myofascial Trigger Points Then and Now: A Historical and Scientific Perspective
This narrative review explores the historical and scientific understanding of myofascial trigger points (MTrPs) and their role in myofascial pain syndrome (MPS). MTrPs are palpable nodules in taut muscle bands, long con…
Remodelling the extracellular matrix in development and disease
This narrative review describes the extracellular matrix (ECM), a dynamic network present in all body tissues that undergoes constant remodeling. This remodeling process is crucial for regulating cell functions like pro…
The effects of grounding (earthing) on inflammation, the immune response, wound healing, and prevention and treatment of chronic inflammatory and autoimmune diseases
This report summarizes research on the effects of "grounding" or "earthing," which involves direct electrically conductive contact with the Earth's surface. The research suggests this contact may influence the body's ph…
The Effects of Vibration and Muscle Fatigue on Trunk Sensorimotor Control in Low Back Pain Patients
This study compared trunk muscle control between people with chronic low back pain (cLBP) and healthy individuals. Researchers found that the cLBP group was less accurate at reproducing a specific amount of force with t…
Fascia and Primo Vascular System
In this review article, the authors explore the idea that the body's network of fascia may be the physical structure corresponding to acupuncture meridians in Traditional Chinese Medicine (TCM). They also discuss the pr…
Understanding Fibroblasts in Order to Comprehend the Osteopathic Treatment of the Fascia
In this review paper, the authors argue that understanding fibroblasts is essential for comprehending and applying osteopathic treatment of the fascia. As the foundational cells of connective tissue, fibroblasts have ma…
Hyaluronan’s Role in Fibrosis: A Pathogenic Factor or a Passive Player?
This 2015 review article explores the role of hyaluronan (HA) in fibrosis, a condition where excessive connective tissue buildup impairs organ function. HA is a key component of the extracellular matrix, known for its h…
Primo-Vascular System as Presented by Bong Han Kim
In the 1960s, researcher Bong Han Kim described a new vascular system, distinct from the blood and lymph systems, which he proposed was involved in tissue regeneration. However, his work was difficult for later scientis…
Hyaluronan, inflammation and breast cancer progression
This narrative review explores the link between inflammation, the tissue component hyaluronan (HA), and breast cancer progression. Cancer cells and surrounding host cells can create an inflamed microenvironment that hel…