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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 793–804 of 1,127 studies · page 67/94With summary
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A2014

A decorin-deficient matrix affects skin chondroitin/dermatan sulfate levels and keratinocyte function

Katerina Nikolovska, Jana K Renke, Oliver Jungmann, Kay Grobe, Renato V Iozzo, Alina D Zamfir, Daniela G Seidler

This study in mice investigated how the absence of a proteoglycan called decorin affects skin structure and function. Researchers found that mice lacking decorin had an altered composition of other sugar molecules (chon…

extracellular matrixDecorinSLRP
A2013

Earthing (Grounding) the Human Body Reduces Blood Viscosity—a Major Factor in Cardiovascular Disease

Gaétan Chevalier, Stephen T Sinatra, James L Oschman, Richard M Delany

This small study investigated how direct physical contact with the earth, known as 'grounding' or 'earthing', affects blood properties. Ten healthy participants were grounded for two hours using conductive patches on th…

fasciaearthinggrounding
A2013

Visceral and Somatic Disorders: Tissue Softening with Frequency-Specific Microcurrent

Carolyn R McMakin, James L Oschman

This review article explores a technique called Frequency-Specific Microcurrent (FSM), which uses microampere-level electrical currents to treat various health conditions. A consistent finding is a rapid and palpable so…

fasciafrequency-specific microcurrentvisceral disease
A2013

Direct magnetic resonance (MR) shoulder arthrography: posterior approach under ultrasonographic guidance and abduction (PAUGA

R F Grasso, E Faiella, P Cimini, R L Cazzato, G Luppi, F Martina, R Del Vescovo, B Beomonte Zobel

This study evaluated a specific technique, called PAUGA, for injecting contrast dye into the shoulder joint before an MRI scan (MR arthrography). Researchers used ultrasound to guide a needle from the back of the should…

ShoulderDirect MR arthrographyUS guidance
A2013

Nociception originating from the crural fascia in rats

T Taguchi, M Yasui, A Kubo, M Abe, H Kiyama, A Yamanaka, K Mizumura

This animal study investigated how the crural fascia, the connective tissue around the lower leg muscles, might be a source of pain signals in rats. Researchers found that this fascia is densely populated with nerve fib…

fasciacrural fascianociceptors
A++2013

The application of matrix rhythm therapy as a new clinical modality in burn physiotherapy programmes

Zübeyir Sarı, Mine Gülden Polat, Bahar Özgül, Onur Aydogdu, Burcu Camcıoglu, Ahmet Hakan Acar, Saadet Ufuk Yurdalan

This study investigated the use of Matrix Rhythm Therapy (MRT) as part of a physiotherapy program for patients with upper extremity burn injuries. A group of patients received a treatment protocol that included whirlpoo…

Matrix Rhythm TherapyBurnsPhysiotherapy and rehabilitation
B2013

Vitamin C further improves the protective effect of glucagon-like peptide-1 on acute hypoglycemia-induced oxidative stress, inflammation, and endothelial dysfunction in type 1 diabetes

ANTONIO CERIELLO, ANNA NOVIALS, EMILIO ORTEGA, SILVIA CANIVELL, LUCIA LA SALA, GEMMA PUJADAS, LOREDANA BUCCIARELLI, MAU…

Acute low blood sugar (hypoglycemia) in people with type 1 diabetes can cause oxidative stress, inflammation, and damage to the lining of blood vessels. This study investigated whether the hormone GLP-1 and vitamin C co…

Oxidative stressdiabetesVitamin C
1A+2013

Stress and Matrix-Responsive Cytoskeletal Remodeling in Fibroblasts

R D Abbott, C Koptiuch, J C Iatridis, A K Howe, G J Badger, H M Langevin

In loose connective tissue, fibroblasts change shape in response to static stretch, which helps the tissue relax. This study investigated whether this response depends on the cell itself or its surrounding environment,…

Fibroblasts; cytoskeleton; dense connective tissue; areolar connective tissue; mechanotransduction
A+2013

Local vitamin-C Injection Reduced Tendon Adhesion in a Chicken Model of Flexor Digitorum Profundus Tendon Injury

Leung-Kim Hung, Sai-Chuen Fu, Yuk-Wa Lee, Tsui-Yu Mok, Kai-Ming Chan

This animal study investigated whether vitamin C could reduce scar tissue formation after a tendon injury. Researchers injured a flexor tendon in chickens and then injected either vitamin C or a saline solution at the s…

Vitamin Chealing tendonadhesion
A++2013

Implementation of Matrix Rhythm Therapy and Conventional Massage in Young Females and Comparison of Their Acute Effects on Circulation

Ferruh Taspinar, Ummuhan Bas Aslan, Nuran Sabir, Ugur Cavlak

This randomized controlled trial compared the acute effects of Matrix Rhythm Therapy and conventional massage on lower leg blood circulation in young, healthy women. Fifteen participants received a single 30-minute sess…

fascia
A2013

Cellulite's aetiology: a review

M de la Casa Almeida, Suarez Serrano, J Rebollo Roldán, J J Jiménez Rejano

In this literature review, researchers examined the underlying causes of cellulite. They found that cellulite is a complex phenomenon with many interacting factors, rather than a single cause. The research points to wom…

Connective tissuecellulites
A++2013

Air ions and mood outcomes: a review and meta-analysis

Vanessa Perez, Dominik D Alexander, William H Bailey

This review and meta-analysis examined 33 studies to investigate how air ions affect human psychological states. The authors found no consistent effects of positive or negative ionization on anxiety, general mood, relax…

systematic reviewepidemiologyMood disorders