Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesSpecific Sizes of Hyaluronan Oligosaccharides Stimulate Fibroblast Migration and Excisional Wound Repair
Hyaluronan (HA) is a molecule important for wound healing, and its effects appear to depend on its size. In this study using cell cultures and animal models, researchers investigated how specific, small fragments of HA…
Ultrasound Elastography: The New Frontier in Direct Measurement of Muscle Stiffness
This 2014 review article describes ultrasound elastography, a technology that can directly measure the mechanical properties of tissue, such as muscle stiffness. The authors suggest that its real-time measurements can a…
The theory and fundamentals of bioimpedance analysis in clinical status monitoring and diagnosis of diseases
Bioimpedance analysis is a noninvasive, low cost and a commonly used approach for body composition measurements and assessment of clinical condition. There are a variety of methods applied for interpretation of measured…
Deformations Experienced in the Human Skin, Adipose Tissue, and Fascia in Osteopathic Manipulative Medicine
This study used a mathematical model to investigate how forces from manual therapy affect the skin, adipose tissue, and fascia. The researchers aimed to understand how much each layer deforms under compression and shear…
Telocytes revisited
This narrative review summarizes findings on telocytes, a relatively new type of cell found in the interstitial, or connective, tissue of many organs. These cells are defined by their small bodies and extremely long, th…
Antioxidants in health and disease
This narrative review summarizes research on antioxidants published since 2010. The main role of antioxidants is to neutralize reactive oxygen species (ROS), which are linked to conditions like cardiovascular disease, c…
Chiropractic Management of Pubic Symphysis Shear Dysfunction in a Patient With Overactive Bladder
This case report describes the chiropractic care of a 24-year-old woman with an overactive bladder, specifically frequent nighttime urination that disrupted her sleep. A physical examination revealed a shear dysfunction…
Clinical and symptomatological reflections: the fascial system
This narrative review discusses the fascial system as a continuous network of connective tissue that gives form and function to the entire body. The authors note that despite its importance in transmitting force, coordi…
Monocyte chemoattractant protein-1-induced excitation and sensitization to mechanical stimulation of mechanosensitive C-fiber afferents in rat skin
In this animal study, researchers investigated the effects of the protein MCP-1, which is involved in inflammation, on nerve endings in the skin. Using skin-nerve preparations from rats, they found that applying MCP-1 d…
Altered Gene Transcription in Human Cells Treated with Ludox® Silica Nanoparticles
This in vitro study investigated how human lung cells react to exposure to Ludox® silica nanoparticles, which are common in industrial and biomedical applications. Using genetic analysis, researchers observed that the c…
Neuroreceptor Activation by Vibration-Assisted Tunneling
This theoretical study used quantum chemical modeling to explore how receptors in the nervous system get activated. The researchers propose a model where a molecule's specific vibrations, like a musical key, may be what…
Dietary Hyaluronic Acid Migrates into the Skin of Rats
In this animal study, researchers investigated whether orally ingested hyaluronic acid could reach the skin in rats. Using a radio-labeled version of hyaluronic acid, they tracked its path through the body after rats we…