Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- B2015
Fibromyalgia: A Critical and Comprehensive Review
Andrea T Borchers, M Eric GershwinThis comprehensive review discusses fibromyalgia as a complex disorder within a spectrum of medically unexplained syndromes. Characterized by widespread pain, fatigue, and sleep disturbances, it is often associated with…
FibromyalgiaChronicpainOpiatesPatient supportTrauma - A2015
Reflections on osteopathic fascia treatment in the peripheral nervous system
Bruno Bordoni, Giovanni BordoniIn this reflective article, the authors discuss the fascia of the peripheral nervous system. They explain that nerves are enclosed in several layers of fascia that must be able to slide, and that impeded sliding can be…
fasciapainfascial treatmentnerve palpation - 1A+2014
Hyaluronan: Biosynthesis and signaling
D Vigetti, E Karousou, M Viola, S Deleonibus, G De Luca, A PassiThis 2014 narrative review discusses hyaluronan (HA), a key component of the extracellular matrix. Beyond its structural role in tissue hydration and architecture, HA is an active signaling molecule. The authors highlig…
extracellular matrixGlycosaminoglycanAMPKO-GlcNacylationHyaluronan receptor - 1A+2014
Painful Connections: Densification Versus Fibrosis of Fascia
P G Pavan, Antonio Stecco, R Stern, Carla SteccoIn this review article, the authors describe two types of fascial changes that can cause pain: densification and fibrosis. Densification is described as a reversible alteration in the viscosity of the loose connective t…
hyaluronanfasciafibrosisdensificationConnective tissue - A2014
Whey protein hydrolysate augments tendon and muscle hypertrophy independent of resistance exercise contraction mode
J Farup, S K Rahbek, M H Vendelbo, A Matzon, J Hindhede, A Bejder, S Ringgard, K VissingThis study investigated the effects of resistance training combined with either whey protein or a placebo on muscle and tendon growth. Twenty-two participants performed 12 weeks of knee extension training, using eccentr…
patellar tendonstrength trainingeccentric trainingconcentric trainingrate of force development - A2014
Chiropractic Management of Pubic Symphysis Shear Dysfunction in a Patient With Overactive Bladder
Robert Cooperstein, Anthony Lisi, Andrew BurdThis case report describes the chiropractic care of a 24-year-old woman with an overactive bladder, specifically frequent nighttime urination that disrupted her sleep. A physical examination revealed a shear dysfunction…
fasciasymphysis pubis dysfunctionpubic symphysispubic symphysis diastasisurinary bladder overactive - A+++2014
The active role of vitamin C in mammalian iron metabolism: much more than just enhanced iron absorption!
Darius J R Lane, Des R RichardsonThis review explores how vitamin C (ascorbate) plays a sophisticated role in mammalian iron metabolism beyond simply enhancing absorption in the gut. Evidence suggests that vitamin C regulates how cells take up, store,…
Ascorbate; Dcytb; Ferritin; Free radicals; HIF; IRP; Iron; Transferrin; Vitamin C - A++2014
Ultraweak photon emission as a non-invasive health assessment: a systematic review
John A Ives, Eduard P A van Wijk, Namuun Bat, Cindy Crawford, Avi Walter, Wayne B Jonas, Roeland van Wijk, Jan van der…This systematic review explores the use of ultraweak photon emission (UPE) as a non-invasive tool for assessing human health. By analyzing 56 studies, researchers found that measuring light particles emitted by the body…
Ultra-weak photon emissionultra-weak bioluminescencehealt assessment - A2014
Definition of the To Be Named Ligament and Vertebrodural Ligament and Their Possible Effects on the Circulation of CSF
Nan Zheng, Xiao-Ying Yuan, Yun-Fei Li, Yan-Yan Chi, Hai-Bin Gao, Xin Zhao, Sheng-Bo Yu, Hong-Jin Sui, John SharkeyIn this cadaver study, researchers investigated connective tissue structures in the upper neck of 30 human specimens. They identified two specific ligaments, the 'to be named ligament' (TBNL) and the vertebrodural ligam…
fasciadura materMyodural Bridgecerebrospinal fluid circulation - B2014
Mechanisms of Myofascial Pain
M Saleet JafriThis 2014 narrative review discusses the potential causes of myofascial pain. Myofascial pain syndrome is a common condition involving painful trigger points in muscle, but its precise mechanisms are not well understood…
fasciaMyofascial painMyofascial trigger points - 1A+2014
Peripheral Mechanisms Contributing to Spasticity and Implications for Treatment
Antonio Stecco, Carla Stecco, P RaghavanThis narrative review explores how changes in connective tissue might contribute to spasticity following a central nervous system injury. The authors suggest that the initial injury can alter the turnover of hyaluronic…
fasciaConnective tissueStrokeCerebral palsyHypertonia - B2014
Pro-Resolving lipid mediators and Mechanisms in the resolution of acute inflammation
Christopher D Buckley, Derek W Gilroy, Charles N SerhanIn this narrative review, the authors explain that the resolution of inflammation is an active, carefully orchestrated process, not just the passive stopping of an inflammatory response. Specific molecules called specia…
acute inflammationpro-resolving mediators