Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2015
Glycosaminoglycans and Proteoglycans in Palmar Fascia of Patients with Dupuytren
Priscilla Carneiro Hirai Nascimento, Elsa Yoko Kobayashi, Luiz Guilherme de Saboya Lenzi, João baptista Gomes dos Santo…In this experimental study, researchers investigated the role of glycosaminoglycans (GAGs), a type of molecule in connective tissue, in Dupuytren's disease. The team analyzed palmar fascia tissue samples from 23 patient…
fasciaProteoglycansdupuytren contractureglycosaminoglycans - A2015
Understanding Fibroblasts in Order to Comprehend the Osteopathic Treatment of the Fascia
Bruno Bordoni, Emiliano ZanierIn this review paper, the authors argue that understanding fibroblasts is essential for comprehending and applying osteopathic treatment of the fascia. As the foundational cells of connective tissue, fibroblasts have ma…
fasciafibroblastosteopathy - A2015
Mitochondrial Dysfunction and Disturbed Coherence: Gate to Cancer
Jirí Pokorný, Jan Pokorný, Alberto Foletti, Jitka Kobilková, Jan Vrba, Jan Vrba JrThis theoretical paper explores the link between cellular energy and cancer. Healthy cells maintain a stable, coherent electrical state through continuous energy production in the mitochondria. The authors propose that…
fasciacancer biophysicsmitochondrial dysfunctionwater orderingmicrotubule oscillations - 1A+2015
Electron microscopy of human fascia lata: focus on telocytes
Joanna Dawidowicz, Sylwia Szotek, Natalia Matysiak, Łukasz Miela!nczyk, Krzysztof MaksymowiczThis study used an electron microscope to examine the types of cells present in the fascia lata, a sheet of connective tissue in the thigh. For the first time, researchers confirmed the existence of a specific cell type…
Fibroblastsmyofibroblastshuman fascia latatransmission electron microscopytelocytes - A2015
Hyaluronan’s Role in Fibrosis: A Pathogenic Factor or a Passive Player?
S Albeiroti, A Soroosh, C A de la MotteThis 2015 review article explores the role of hyaluronan (HA) in fibrosis, a condition where excessive connective tissue buildup impairs organ function. HA is a key component of the extracellular matrix, known for its h…
hyaluronanfasciafibrosis - A+++2015
Functional locomotor consequences of uneven forefeet for trot symmetry in individual riding horses
Nathan Wiggers, Sandra L P Nauwelaerts, Sarah Jane Hobbs, Sophie Bool, Claudia F Wolschrijn, Willem BackThis study investigated how horses with uneven forefeet, where the angle differs between left and right, move at a trot. Researchers found that the flatter foot experiences higher loading, including greater braking forc…
asymmetryriding horsesuneven feethoof angle - C2015
Hyaluronic acid and wound healing
M G Neuman, R M Nanau, L Oruna-Sanchez, G CotoIn this systematic review, researchers compiled studies on hyaluronic acid (HA) and wound healing published from 2010–2014. The review found that HA is used for tissue regeneration, either alone or in combination with o…
hyaluronanwound healing - A+++2015
Swing phase kinematics of horses trotting over poles
S Brown, N C Stubbs, L J Kaiser, M Lavagnino, H M ClaytonThis study investigated how horses are affected by trotting over poles, a common therapeutic exercise used to restore joint range of motion. Researchers aimed to determine if lifting the limbs higher to clear obstacles…
coordination; horse; physiotherapy; rehabilitation - A+++2015
Optimal Vitamin D Supplementation Levels for Cardiovascular Disease Protection
Sebastian T Lugg, Phillip A Howells, David R ThickettThis narrative review explores the growing body of evidence linking vitamin D to cardiovascular health. While traditionally associated with bone health, data suggests vitamin D status may be a marker for, and possibly a…
vitamin DCardiovascular disease25-hydroxyvitamin D3 - A2015
Biological electric fields and rate equations for biophotons
M Alvermann, Y N Srivastava, J Swain, A WidomThis theoretical paper explores the relationship between biophotons (light emitted by living organisms) and the electric fields within biological systems. The authors note that biophoton intensity is linked to the stren…
biophotonsElectric fieldsNonlinear rate equations - A+2015
An overview of the beneficial effects of hydrolysed collagen intake on joint and bone health and on skin ageing
Teresa Figueres Juher, Esther Basés PérezThis narrative review summarizes research on hydrolysed collagen (HC) and its impact on joint, bone, and skin health. Evidence suggests that these small collagen peptides are highly bioavailable and accumulate in connec…
supplementationOsteoporosishydrolysate collagenosteartrithis - A2015
Effects of non-pharmacological interventions on inflammatory biomarker expression in patients with fibromyalgia: a systematic review
Kenji Sanada, Marta Alda Díez, Montserrat Salas Valero, María Cruz Pérez-Yus, Marcelo M P Demarzo, Mauro García-Toro, J…This systematic review examined how non-drug treatments affect inflammatory markers in people with fibromyalgia. Researchers analyzed 12 studies involving 536 participants who underwent exercise, dietary, or multidiscip…
fasciaFibromyalgiapaincytokinessleep quality