Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2015
Estrogen inhibits lysyl oxidase and decreases mechanical function in engineered ligaments
Cassandra A Lee, Ann Lee-Barthel, Louise Marquino, Natalie Sandoval, George R Marcotte, Keith BaarThis lab study investigated why women are more likely to rupture their anterior cruciate ligament (ACL) than men, focusing on the role of estrogen. Researchers used human ACL cells to create engineered ligaments in a la…
ACL; exercise; tendon; ultimate tensile strength - A2015
Cellulite treatment: a comprehensive literature review
Irene Zerini, Andrea Sisti, Roberto Cuomo, Serena Ciappi, Francesco Russo, Cesare Brandi, Carlo D’Aniello, Giuseppe NisiIn this 2015 literature review, researchers compiled the results from various cellulite treatments. They analyzed 73 clinical studies involving human subjects, most of whom were women. The evaluated treatments included…
elasticitycellulitefatty tissue - A+2015
Osmotic pressure induced tensile forces in tendon collagen
Admir Masic, Luca Bertinetti, Roman Schuetz, Shu-Wei Chang, Till Hartmut Metzger, Markus J Buehler, Peter FratzlResearchers investigated the role of water in tendon collagen using a combination of experiments and computer modeling. They found that water is a crucial part of the collagen molecule's structure. When water is removed…
collagenOsmotic pressurewater - A2015
Essential Experimental Methods for Identifying Bonghan Systems as a Basis for Korean Medicine: Focusing on Visual Materials from Original Papers and Modern Outcomes
Hoon-Gi Kim, Byung-Cheon Lee, Ki-Bog LeeThis narrative review examines methods for identifying the so-called Bonghan system, also known as the primo vascular system (PVS). This system was originally proposed in the 1960s as the anatomical basis for acupunctur…
fasciaacupunctureprimo vascular systembongan system - A2015
Primo Vascular System: A Unique Biological System Shifting a Medical Paradigm
Bruno Chikly, Paul Roberts, Jörgen QuaghebeurThis article describes the primo vascular system (PVS), a unique biological system distinct from the arteriovenous and lymphatic systems. Research suggests the PVS has immune and endocrine functions and plays a role in…
fasciaprimo vascular system - A2015
Primo Vascular System: An Endothelial-to-Mesenchymal Potential Transitional Tissue Involved in Gastric Cancer Metastasis
An Ping, Su Zhendong, Qu Rongmei, Dai Jingxing, Chen Wei, Zhou Zhongyin, Luo Hesheng, Kwang-Sup SohThe primo vascular system (PVS) is described as a distinct circulatory network beyond the blood and lymphatic systems. This study investigated the role this system might play in the spread of gastric cancer. The researc…
fasciacancermetastasisprimo vascular system - A2015
Investigation of meningomyovertebral structures within the upper cervical epidural space: a sheet plastination study with clinical implications
Frank Scali, Matthew E Pontell, Lance G Nash, Dennis E EnixThis cadaver study investigated soft-tissue connections within the epidural space of the upper cervical spine using dissection and a technique called sheet plastination. The researchers found consistent connections wher…
fasciacervical spineMyodural Bridgedural lacerationsepidural space - 1A+++2015
Viscoelastic Properties of Hyaluronan in Physiological Conditions
Mary K Cowman, Tannin A Schmidt, Preeti Raghavan, Antonio SteccoHyaluronan (HA) is a molecule that gives the fluid in our connective tissues its viscous, gel-like quality. This viscosity is crucial for the smooth gliding of fascial layers against muscles and other tissues. Factors l…
Hyalyronian acidhaviscositylubricationviscoelasticity - 1A+2015
Gymnastic Training and Dynamic Mobilization Exercises Improve Stride Quality and Increase Epaxial Muscle Size in Therapy Horses
Kátia de Oliveira, Ricardo V G Soutello, Ricardo da Fonseca, Ciniro Costa, Paulo R de L Meirelles, Daniele F Fachiolli,…This study on therapy horses investigated how specific exercises affect stride and back muscles. Over three months, nine horses were divided into three groups: a control group, one doing dynamic mobilization exercises,…
Hippotherapytherapeutic exercisedynamic mobilization exercisephysical trainingthree-dimensional movement - A+2015
The Heart, the Brain, and the Regulation of Emotion
Sarah N Garfinkel, Jessica A Eccles, Hugo D CritchleyThis research entry, summarized from its title, appears to explore the relationship between the heart, the brain, and how emotions are managed. It likely discusses how signals from the cardiovascular system, specificall…
psychology.psychiatryemotionsbody signals - A++2015
Influence of different intensities of vibration on proliferation and differentiation of human periodontal ligament stem cells
Chunxiang Zhang, Yanqin Lu, Linkun Zhang, Yang Liu, Yi Zhou, Yangxi Chen, Haiyang YuIn this laboratory study, researchers investigated how low-magnitude, high-frequency vibration affects stem cells from the human periodontal ligament, the tissue that holds teeth in the jaw. The results suggest that vib…
Proliferationmechanical vibrationperiodontal ligament stem cellsosteogenesismagnitude - A2015
Hyaluronan’s Role in Fibrosis: A Pathogenic Factor or a Passive Player?
S Albeiroti, A Soroosh, C A de la MotteThis 2015 review article explores the role of hyaluronan (HA) in fibrosis, a condition where excessive connective tissue buildup impairs organ function. HA is a key component of the extracellular matrix, known for its h…
hyaluronanfasciafibrosis