Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2021
Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan
Amrendra Mishra, Hamed Mirzaei, Novella Guidi, Manlio Vinciguerra, Alice Mouton, Marina Linardic, Francesca Rappa, Rosa…This animal study on mice investigated how periodic cycles of a fasting-mimicking diet (FMD) affect health when consuming a high-fat, high-calorie diet. Researchers found that five days of FMD every month reduced the ac…
fasting; fasting-mimicking diet; inflammation; intermittent fasting; high fat diet; cardiovascular disease - A+++2021
The challenges of chronic pain and fatigue
Jessica A Eccles, Kevin A DaviesIn this review article, the authors explore the challenges of chronic pain and fatigue, two common and frequently overlapping symptoms. They discuss possible underlying biological associations, including connective tiss…
Fibromyalgiapainfatiguehypermobilityrheumatology - A+2021
Time-Restricted Eating, Intermittent Fasting, and Fasting-Mimicking Diets in Weight Loss
Maura Fanti, Amrendra Mishra, Valter D Longo, Sebastian BrandhorstThis literature review examines the effects of time-restricted eating (TRE), intermittent fasting (IF), and fasting-mimicking diets (FMD) on weight loss. While these interventions are popular for their potential health…
Fasting-mimicking diet; Intermittent fasting; Obesity; Time-restricted eating; Weight loss - A++2021
Physical Agent Modalities in Early Osteoarthritis: A Scoping Review
Giulia Letizia Mauro, Dalila Scaturro, Francesca Gimigliano, Marco Paoletta, Sara Liguori, Giuseppe Toro, Giovanni Iola…This scoping review investigated the role of physical agent modalities in treating early osteoarthritis (EOA). Researchers searched for studies on treatments like TENS, extracorporeal shockwave therapy (ESWT), ultrasoun…
osteoarthritis; early osteoarthritis; rehabilitation; physical therapy modalities; physical agents; electric stimulation therapy; pulsed electromagnetic field; extracorporeal shockwave therapy; vibration therapy - A+++2021
Evidence for continuity of interstitial spaces across tissue and organ boundaries in humans
Odise Cenaj, Douglas H R Allison, Rami Imam, Briana Zeck, Lilly M Drohan, Luis Chiriboga, Jessica Llewellyn, Cheng Z Li…Researchers investigated whether the fluid-filled spaces within our connective tissues, known as the interstitium, are isolated within organs or form a continuous network throughout the body. By tracking particles like…
continuityinterstitiumfluid - A+++2021
Estrogenic Effect of Salvia officinalis Extract on Reproductive Function of Female Mice and Identification of Its Phenolic Content
Sabah H Elgayed, Elham A Afify, Hanan A Amin, Ahmed A H AbdellatifThis animal study on mice investigated whether sage (Salvia officinalis) extract could serve as a natural alternative to estrogen replacement therapy. Researchers found that sage contains phytoestrogens, specifically qu…
Natural phytoestrogens; female mice.; menopause; natural estrogen; phenolic content; saliva officinalis; uterotrophic activity - A+++2021
Potential Nociceptive Role of the Thoracolumbar Fascia: A Scope Review Involving In Vivo and Ex Vivo Studies
Larissa Sinhorim, Mayane Dos Santos Amorim, Maria Eugênia Ortiz, Edsel Balduino Bittencourt, Gianluca Bianco, Fabiana C…This scoping review compiles research on how the thoracolumbar fascia (TLF) in the lower back contributes to pain perception. By examining both animal and human studies, the authors find that the fascia is richly suppli…
ex vivo; fascia; in vivo; innervation; lower back pain; nociceptor; pain; scoping review; thoracolumbar fascia - A+++2021
Vitamins, the gut microbiome and gastrointestinal health in humans
Van T Pham, Susanne Dold, Ateequr Rehman, Julia K Bird, Robert E SteinertThis narrative review explores how various vitamins influence the gut microbiome and gastrointestinal health in humans. The research suggests that vitamins such as A, B, C, D, and E may increase the diversity of benefic…
Gastrointestinal health; Gut; Gut barrier function; Microbiome; Micronutrient; Vitamins - A+++2021
The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review
Mishti Khatri, Robert J Naughton, Tom Clifford, Liam D Harper, Liam CorrThis systematic review evaluated 15 randomized controlled trials on how collagen peptide supplementation interacts with exercise to affect joint health and recovery. The findings suggest that collagen may be most effect…
Fat free mass; Gelatin; Joint health; Joint pain; Muscle damage; Protein - A2021
Neural Coding of Vibration Intensity
Wanjoo Park, Sung-Phil Kim, Mohamad EidThis study investigated how the brain processes different intensities of vibration using electroencephalography (EEG). Researchers applied no, low, or high-intensity vibration to participants' index fingers while measur…
vibrationhapticsneural signal processingsensationalpha ERD - A+++2021
Myofascial pain in females and personalized care: The key role played by sex hormones
Caterina Fede, Carmelo Pirri, Raffaele De Caro, Carla SteccoBased on its title, this publication appears to explore the relationship between sex hormones and myofascial pain specifically in females. The authors suggest that hormonal factors play a key role in this type of pain.…
Myofascial painsex hormonesfemales - A++2021
Fascia and Tensegrity The Quintessence of a Unified Systems Conception
John SharkeyThis theoretical paper proposes a new way of viewing the human body, moving beyond the traditional mechanical model of parts and levers. The author suggests the body is better understood as a unified system based on ten…
Fascia; Tensegrity; Continuity; Unified Systems; Biotensegrity; Stability; Embryology