Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2015
Glycine improves biochemical and biomechanical properties following inflammation of the achilles tendon
Cristiano Pedrozo Vieira, Letícia Prado De Oliveira, Flávia Da Ré Guerra, Marcos Dos Santos De Almeida, Maria Cristina…This animal study investigated the effect of the amino acid glycine on inflamed Achilles tendons in rats. Researchers induced inflammation and then fed one group of rats a diet supplemented with 5% glycine. After 22 day…
achilles tendon; extracellular matrix; glycine; inflammatory process; tendinopathy. - A+2015
An overview of the beneficial effects of hydrolysed collagen intake on joint and bone health and on skin ageing
Teresa Figueres Juher, Esther Basés PérezThis narrative review summarizes research on hydrolysed collagen (HC) and its impact on joint, bone, and skin health. Evidence suggests that these small collagen peptides are highly bioavailable and accumulate in connec…
supplementationOsteoporosishydrolysate collagenosteartrithis - A++2015
Neurovisceral phenotypes in the expression of psychiatric symptoms
Jessica A Eccles, Andrew P Owens, Christopher J Mathias, Satoshi Umeda, Hugo D CritchleyThis narrative review explores the idea that vulnerability to anxiety may be rooted in inherent physical differences in how the body is regulated. The authors focus on conditions like joint hypermobility, Postural Tachy…
joint hypermobilityAnxietypostural tachycardia syndromevasovagal syncopepsychiatry - A+++2015
Swing phase kinematics of horses trotting over poles
S Brown, N C Stubbs, L J Kaiser, M Lavagnino, H M ClaytonThis study investigated how horses are affected by trotting over poles, a common therapeutic exercise used to restore joint range of motion. Researchers aimed to determine if lifting the limbs higher to clear obstacles…
coordination; horse; physiotherapy; rehabilitation - B2015
Myofascial Trigger Points Then and Now: A Historical and Scientific Perspective
Jay P Shah, Nikki Thaker, Juliana Heimur, Jacqueline V Aredo, Siddhartha Sikdar, Lynn H GerberThis narrative review explores the historical and scientific understanding of myofascial trigger points (MTrPs) and their role in myofascial pain syndrome (MPS). MTrPs are palpable nodules in taut muscle bands, long con…
fasciaMyofascial trigger points - A++2015
BioTensegrity Fascia and the fallacy of biomechanics. Part 1
John SharkeyThis conceptual article introduces Biotensegrity as an emerging model for understanding human anatomy. It challenges traditional biomechanics by viewing the body as a continuous tensional network in which fascia plays a…
biotensegrityBiomechanics - A+++2015
Functional locomotor consequences of uneven forefeet for trot symmetry in individual riding horses
Nathan Wiggers, Sandra L P Nauwelaerts, Sarah Jane Hobbs, Sophie Bool, Claudia F Wolschrijn, Willem BackThis study investigated how horses with uneven forefeet, where the angle differs between left and right, move at a trot. Researchers found that the flatter foot experiences higher loading, including greater braking forc…
asymmetryriding horsesuneven feethoof angle - A2015
Mitochondrial Dysfunction and Disturbed Coherence: Gate to Cancer
Jirí Pokorný, Jan Pokorný, Alberto Foletti, Jitka Kobilková, Jan Vrba, Jan Vrba JrThis theoretical paper explores the link between cellular energy and cancer. Healthy cells maintain a stable, coherent electrical state through continuous energy production in the mitochondria. The authors propose that…
fasciacancer biophysicsmitochondrial dysfunctionwater orderingmicrotubule oscillations - A2015
Understanding Fibroblasts in Order to Comprehend the Osteopathic Treatment of the Fascia
Bruno Bordoni, Emiliano ZanierIn this review paper, the authors argue that understanding fibroblasts is essential for comprehending and applying osteopathic treatment of the fascia. As the foundational cells of connective tissue, fibroblasts have ma…
fasciafibroblastosteopathy - C2015
Collagen Crosslinking Does Not Dictate Stiffness in a Transgenic Mouse Model of Skeletal Muscle Fibrosis
M A Chapman, R Pichika, R L LieberIn this animal study on mice, researchers investigated why fibrotic, or scarred, skeletal muscle becomes so stiff. While it is known that fibrosis involves an increase in collagen, the amount of collagen alone does not…
fibrosisstiffnesscollagen cross-linking - C2015
Proteoglycan form and function: A comprehensive nomenclature of proteoglycans
Renato V Iozzo, Liliana SchaeferIn this review article, the authors propose a new, comprehensive classification system for proteoglycans, a group of molecules important to connective tissue structure and function. The classification is based on three…
GlycosaminoglycanAngiogenesisProteoglycanCancer growthGrowth factor modulation - A++2015
Fruit, vegetable and vitamin C intakes and plasma vitamin C: cross-sectional associations with insulin resistance and glycaemia in 9-10 year-old children
A S Donin, J E Dent, C M Nightingale, N Sattar, C G Owen, A R Rudnicka, M R Perkin, A M Stephen, S A Jebb, D G Cook, P…This cross-sectional study of over 2000 children in the UK examined the relationship between vitamin C and risk factors for type 2 diabetes. Researchers found that higher levels of vitamin C in the blood were associated…
Vitamin Cinsulin resistensglycaemiadiabetes type 2