Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesMicrobiota-dependent sequelae of acute infection compromise tissue-specific immunity
A single acute infection can have long-term consequences for tissue-specific immunity, even after the pathogen is cleared. This study found that following a gut infection with Yersinia pseudotuberculosis, sustained infl…
BioTensegrity Fascia and the fallacy of biomechanics, Part 2.
In this conceptual article, the second in a series, the author introduces BioTensegrity as an alternative to classical biomechanics. He argues that traditional models of animal and human movement, which date back to the…
Hyaluronan Controls the Deposition of Fibronectin and Collagen and Modulates TGF-β1 Induction of Lung Myofibroblasts
This study investigated how hyaluronan (HA), a key component of the extracellular matrix, influences the formation of myofibroblasts—cells involved in tissue scarring and fibrosis. Researchers observed that while HA lev…
The content and size of hyaluronan in biological fluids and tissues
Hyaluronan is a simple sugar polymer found throughout the body's tissues and fluids. It is typically produced as a very large, high-molecular-mass molecule. This narrative review notes that during processes like inflamm…
Glycosaminoglycans and Proteoglycans in Palmar Fascia of Patients with Dupuytren
In this experimental study, researchers investigated the role of glycosaminoglycans (GAGs), a type of molecule in connective tissue, in Dupuytren's disease. The team analyzed palmar fascia tissue samples from 23 patient…
Fruit, vegetable and vitamin C intakes and plasma vitamin C: cross-sectional associations with insulin resistance and glycaemia in 9-10 year-old children
This cross-sectional study of over 2000 children in the UK examined the relationship between vitamin C and risk factors for type 2 diabetes. Researchers found that higher levels of vitamin C in the blood were associated…
Mitochondrial Dysfunction and Disturbed Coherence: Gate to Cancer
This theoretical paper explores the link between cellular energy and cancer. Healthy cells maintain a stable, coherent electrical state through continuous energy production in the mitochondria. The authors propose that…
Multi-frequency bioimpedance and myofascial release therapy: An equine “AtlasOrange1” validation study
This study on horses explored whether a device using multi-frequency bioimpedance analysis (mf-BIA) could objectively measure myofascial tension. Researchers compared the device's readings with a veterinarian's manual a…
Understanding Fibroblasts in Order to Comprehend the Osteopathic Treatment of the Fascia
In this review paper, the authors argue that understanding fibroblasts is essential for comprehending and applying osteopathic treatment of the fascia. As the foundational cells of connective tissue, fibroblasts have ma…
Duration and Magnitude of Myofascial Release in 3-Dimensional Bioengineered Tendons: Effects on Wound Healing
This laboratory study investigated how myofascial release (MFR) affects wound healing in bioengineered tendons. Researchers created a wound in the tendon models and then applied different magnitudes and durations of str…
Efficacy of phytoestrogens for menopausal symptoms: a meta-analysis and systematic review
This systematic review and meta-analysis of 15 randomized controlled trials examined the effectiveness of plant-based estrogens, known as phytoestrogens, for relieving menopausal symptoms. The findings suggest that phyt…
Structural and functional features of central nervous system lymphatics
The central nervous system (CNS) was long thought to lack a conventional lymphatic drainage system. In this study, however, researchers discovered functional lymphatic vessels within the meninges, the membranes surround…