Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesPiezo2 is the principal mechanotransduction channel for proprioception
Proprioception is the sense of where our body parts are in space. In this animal study, researchers investigated the molecular sensor responsible for this ability in mice. They found that an ion channel called Piezo2 wa…
Microbiota-dependent sequelae of acute infection compromise tissue-specific immunity
A single acute infection can have long-term consequences for tissue-specific immunity, even after the pathogen is cleared. This study found that following a gut infection with Yersinia pseudotuberculosis, sustained infl…
Human Recombinant Hyaluronidase Injections For Upper Limb Muscle Stiffness in Individuals With Cerebral Injury: A Case Series
This case series investigated injections of the enzyme hyaluronidase to treat upper limb muscle stiffness in 20 individuals with cerebral injury. The researchers hypothesized that an accumulation of hyaluronan in the mu…
Hyaluronic Acid in Inflammation and Tissue Regeneration
This review article summarizes the role of hyaluronic acid (HA) in tissue healing. As a main component of the extracellular matrix, HA is a key player in tissue regeneration. Interestingly, its effects depend on its mol…
Remote effects of lower limb stretching: preliminary evidence for myofascial connectivity?
This study investigated whether stretching the lower body could affect neck mobility. Twenty-six healthy participants were divided into two groups, with one group performing static stretches for the calf and hamstring m…
Telocytes and Their Extracellular Vesicles—Evidence and Hypotheses
This narrative review discusses telocytes, a relatively new type of interstitial cell found throughout the body's connective tissues. These cells are characterized by long projections and are involved in communication b…
New evidence of a dynamic fascial maintenance and self-repair process
This 2016 publication by Leon Chaitow has not yet been summarized in detail. Based on its title, the article appears to present new findings that highlight the dynamic processes of fascial maintenance and self-repair. W…
Connecting (T)issues: How Research in Fascia Biology Can Impact Integrative Oncology
Many cancer patients use complementary therapies like massage, acupuncture, and yoga to improve their quality of life. This review article suggests these treatments may have further benefits by affecting the body's conn…
Cystocele and functional anatomy of the pelvic floor: review and update of the various theories
This narrative review examines different anatomical theories about how the pelvic floor supports the bladder. The researchers summarize that this support involves a complex interplay of the pubocervical fascia, endopelv…
Intermuscular force transmission along myofascial chains: a systematic review
This systematic review examined evidence for force transmission along continuous lines of muscle and fascia, often called myofascial chains. Researchers analyzed nine studies of moderate to excellent quality that invest…
Is remote stretching based on myofascial chains as effective as local exercise? A randomised-controlled trial
This randomized controlled trial investigated whether stretching the lower limbs could improve neck mobility as effectively as direct neck stretching. Researchers divided 63 healthy participants into three groups: one s…
Vitamin C Protects Chondrocytes against Monosodium Iodoacetate-Induced Osteoarthritis by Multiple Pathways
In this study using rat and cell models, researchers investigated if vitamin C could protect cartilage cells against osteoarthritis-like damage. The results showed that vitamin C reduced oxidative stress, inflammation,…