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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 613–624 of 736 studies · page 52/62Since 2015
Clear
A+++2016

Efficacy of an orally administered combination of hyaluronic acid, chondroitin sulfate, curcumin and quercetin for the prevention of recurrent urinary tract infections in postmenopausal women

M Torella, F Del Deo, A Grimaldi, S A Iervolino, M Pezzella, C Tammaro, P Gallo, C Rappa, P De Franciscis, N Colacurci

This prospective study evaluated whether an oral supplement containing hyaluronic acid, chondroitin sulfate, curcumin, and quercetin could prevent recurrent urinary tract infections (UTIs) in postmenopausal women. Resea…

Curcumin; Estrogen; Glycosaminoglycans; Quercetin; Urinary tract infections
A++2016

Can fascia’s characteristics be influenced by manual therapy

Serge Gracovetsky

This theoretical essay investigates the fundamental properties of collagen, a key component of fascia. The author explores how manual therapy might relate to the necessity of maintaining collagen's strength under load.…

Collagen; Models; MMP; Water
A++2016

Ultra-weak photon emission in healthy subjects and patients with type 2 diabetes: evidence for a non-invasive diagnostic tool

Meina Yang, Wenyu Ding, Yanli Liu, Hua Fan, Rajendra P Bajpai, Jialei Fu, Jingxiang Pang, Xiaolei Zhao, Jinxiang Han

All living organisms emit extremely faint light, known as ultra-weak photon emission (UPE). This study investigated whether these light emissions differ between healthy individuals and people with type 2 diabetes. Resea…

fasciaphoton emissionbiological systems
A+++2016

Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells

Brett A Morris, Brian Burkel, Suzanne M Ponik, Jing Fan, John S Condeelis, Julio A Aguirre-Ghiso, James Castracane, Joh…

This study used a 3D in vitro model to investigate how the density of the collagen matrix influences the metabolism of breast cancer cells. The researchers observed that a high-density extracellular matrix drives a meta…

Breast cancer; Collagen; Matrix density; Metabolism
A+2016

The relationship between pelvic alignment and dysmenorrhea

Moon-Jeong Kim, Il-Hun Baek, Bong-Oh Goo

This study investigated the relationship between pelvic alignment and dysmenorrhea (menstrual pain). Researchers compared 102 women, divided into a group with menstrual pain and a group without, using 4D imaging to meas…

AlignmentDysmenorrheaPelvic torsion
A+++2016

A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms

In Young Choi, Laura Piccio, Patra Childress, Bryan Bollman, Arko Ghosh, Sebastian Brandhorst, Jorge Suarez, Andreas Mi…

This study investigates how a periodic fasting-mimicking diet (FMD) affects symptoms of multiple sclerosis (MS) using mouse models and preliminary human trials. In animal models, the diet reduced inflammation and promot…

Fasting-mimicking diet; Intermittent fasting; Time-restricted eating; autoimmunity; multiple sclerosis
A2016

The Physical Mechanism for Retinal Discrete Dark Noise: Thermal Activation or Cellular Ultraweak Photon Emission?

Vahid Salari, Felix Scholkmann, Istvan Bokkon, Farhad Shahbazi, Jack Tuszynski

The visual 'static' or 'noise' we perceive in complete darkness has long been a puzzle. The conventional explanation is that random thermal energy causes photoreceptor cells in the retina to fire, but this model doesn't…

Biophotons
A+2016

Acute effects of muscle stretching on physical performance, range of motion, and injury incidence in healthy active individuals: a systematic review

David G Behm, Anthony J Blazevich, Anthony D Kay, Malachy McHugh

This systematic review examines how different types of stretching (static, dynamic, and PNF) affect performance, range of motion (ROM), and injury risk in healthy individuals. The findings suggest that static stretching…

ballistic stretch; dynamic stretch; facilitation neuromusculaire proprioceptive; flexibility; flexibilité; proprioceptive neuromuscular facilitation; static stretch; warm-up
A++2016

Estrogen and Pelvic Organ Prolapse

Ling Zhou, Anna Junjie Shangguan, Stacy Ann Kujawa, Katarzyna Bochenska, Lanmei Zhang, Serdar E Bulun, Hong Zhao

This narrative review explores the relationship between estrogen and pelvic organ prolapse (POP), a condition where pelvic organs descend from their normal positions. Research suggests that low estrogen levels, particul…

Pelvic organ prolapse; Estrogen; Estrogen receptor; Collagen; Matrix metalloproteinases
C2016

Coordinated integrin activation by actin-dependent force during T-cell migration

P Nordenfelt, H L Elliott, T A Springer

Researchers investigated how immune cells, specifically T-cells, generate the force needed to move. Using fluorescent tension sensors, they visualized the tension within integrins, which are proteins that help cells gri…

cytoskeletonIntegrinsactin
A+++2016

Nutraceutical supplement in the management of tendinopathies: a systematic review

Federico Fusini, Salvatore Bisicchia, Carlo Bottegoni, Antonio Gigante, Fabio Zanchini, Alberto Busilacchi

This systematic review examines the effects of various nutraceuticals, such as glucosamine, chondroitin, vitamin C, and curcumin, in managing tendon disorders. While preclinical research on cells and animals shows promi…

arginine alpha-keto-glutarate; ascorbate; boswellic acid; curcumin; oral supplement; tendon disorder
A++2016

Three Case Reports of Successful Vibration Therapy of the Plantar Fascia for Spasticity Due to Cerebral Palsy-Like Syndrome, Fetal-Type Minamata Disease

Fusako Usuki, Satsuki Tohyama

This series of case reports describes the long-term effects of vibration therapy on lower-limb spasticity in three patients with fetal-type Minamata disease, a condition with symptoms similar to cerebral palsy. Research…

spasticityvibration therapyFDM