Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2017
Spontaneous photon emission: A promising non-invasive diagnostic tool for breast cancer
Xiaolei Zhao, Jingxiang Pang, Jialei Fu, Yong Wang, Meina Yang, Yanli Liu, Hua Fan, Liewei Zhang, Jinxiang HanIn this animal study, researchers investigated if ultra-weak light emission from the body, called spontaneous photon emission (SPE), could detect breast cancer. They measured light from the skin of mice with breast canc…
Breast cancerSpontaneous photon emission (SPE)Preliminary screeningCluster analysisOxidative metabolic - A2017
Adhesive Capsulitis of the Shoulder Joint: Value of Glenohumeral Distance on Magnetic Resonance Arthrography
Kyu Hong Lee, Hee Jin Park, So Yeon Lee, In Young Youn, Eugene Kim, Jai Hyung Park, Se Jin ParkResearchers investigated a new way to help diagnose adhesive capsulitis (frozen shoulder) using a specific type of MRI called MR arthrography. They measured the distance between the ball and socket of the shoulder joint…
Adhesive capsulitisMR imagingShoulderArthrography - B2017
Stretching Reduces Skin Thickness and Improves Subcutaneous Tissue Mobility in a Murine Model of Systemic Sclerosis
Y Xiong, L Berrueta, K Urso, Sara Olenich, Igla Muskaj, G J Badger, A Aliprantis, R Lafyatis, H M LangevinThis animal study investigated the effects of stretching on systemic sclerosis, a condition that causes skin inflammation and fibrosis. Using a mouse model of the disease, researchers found that ten minutes of daily str…
inflammationfibrosisSystemic sclerosisStretchingscleroderma - C2017
X-Rays Effects on Cytoskeleton Mechanics of Healthy and Tumor Cells
Valeria Panzetta, Marta De Menna, Ida Musella, Mariagabriella Pugliese, Maria Quarto, Paolo A. Netti, Sabato FuscoThis study investigated how X-ray radiation affects the internal structure, or cytoskeleton, of both healthy cells and tumor cells in a lab setting. Researchers exposed both cell types to different doses of radiation an…
X-rays; Cytoskeleton; Mechanobiology; Focal Adhesion; Particle Tracking; Microrheology - A+++2017
Electric Nutrition: The Surprising Health and Healing Benefits of Biological Grounding (Earthing)
Stephen T Sinatra, James L Oschman, Gaétan Chevalier, Drew SinatraThis narrative review summarizes research on grounding (earthing), which involves direct physical contact with the Earth's surface. The authors suggest that grounding may provide a form of "electric nutrition" with pote…
Grounding - A++2017
Measuring ultra-weak photon emission as a non-invasive diagnostic tool for detecting early-stage type 2 diabetes: A step toward personalized medicine
Mengmeng Sun, Eduard Van Wijk, Slavik Koval, Roeland Van Wijk, Min He, Mei Wang, Thomas Hankemeier, Jan van der GreefThis study investigated whether ultra-weak photon emission (UPE)—a very faint light emitted by the body—could help identify different subtypes of pre-diabetes. Researchers had practitioners of Traditional Chinese Medici…
biophotonsTraditional Chinese medicin-based diagnosticsPersonalized medicineType 2 diabetesUltra-weak photon emission (UPE) - A++2017
Spontaneous ultra-weak photon emission in correlation to inflammatory metabolism and oxidative stress in a mouse model of collagen-induced arthritis
Min He, Eduard van Wijk, Herman van Wietmarschen, Mei Wang, Mengmeng Sun, Slavik Koval, Roeland van Wijk, Thomas Hankem…In this animal study, researchers investigated a mouse model of rheumatoid arthritis using two techniques: metabolomics (the analysis of metabolic products) and ultra-weak photon emission (UPE), which measures extremely…
biophotonsUltra-weak photon emissionSystems biologyCollagen-induced arthritisCorrelation networks - C2017
Concurrent validity of pain scales in individuals with myofascial pain and fibromyalgia
Scott W Cheatham, Morey J Kolber, Monique Mokha, William J HanneyResearchers investigated the reliability of two common tools for measuring pain: the Numeric Pain Rating Scale (NPRS), where patients rate pain from 0 to 10, and the Visual Analog Scale (VAS). The study included 60 part…
Myofascial painFibromyalgiapain scales - A2017
Don’t Forget the Abdominal Wall: Imaging Spectrum of Abdominal Wall Injuries after Nonpenetrating Trauma
Shanna A Matalon, Reza Askari, Jonathan D Gates, Ketan Patel, Aaron D Sodickson, Bharti KhuranaAbdominal wall injuries from non-penetrating trauma are relatively common but are often overlooked in the emergency department. This can happen because more severe, distracting injuries draw attention away, or because t…
abdominal wallabdominal wall injuriesabdominal wall herniaabdominal wall muscle injurycostochondral rib injury - A++2017
Touch, Tension, and Transduction - The Function and Regulation of Piezo Ion Channels
Jason Wu, Amanda H Lewis, Jörg GrandlThis narrative review explores Piezo1 and Piezo2, specialized proteins that act as the body's primary mechanical sensors. These ion channels convert physical forces like touch, tension, and fluid flow into electrical si…
Mechanotransductionpiezo - A+2017
Quantitative tissue parameters of Achilles tendon and plantar fascia in healthy subjects using a handheld myotonometer
Sarah Orner, Wolfgang Kratzer, Julian Schmidberger, Beate GrünerThis study examined the mechanical properties of the Achilles tendon and plantar fascia in over 150 healthy adults using a handheld device called a MyotonPRO. The goal was to establish baseline normal values for tissue…
fasciaachilles tendonplantar fasciaMyotonePRO - A++2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study
Paul E Marik, Vikramjit Khangoora, Racquel Rivera, Michael H Hooper, John CatravasIn this retrospective before-after study, researchers investigated the effect of a combination therapy of intravenous vitamin C, hydrocortisone, and thiamine for patients with severe sepsis and septic shock. They compar…
corticosteroid; hydrocortisone; septic shock; thiamine; vitamin C