Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2017
Non-contrast MRI diagnosis of adhesive capsulitis of the shoulder
Andrew S Chi, John Kim, Suzanne S Long, William B Morrison, Adam C ZogaThis study investigated whether a standard MRI without contrast dye could be used to reliably diagnose adhesive capsulitis, also known as frozen shoulder. Researchers reviewed MRIs for specific signs, such as a thickene…
MRIfrozen shoulderAdhesive capsulitisNoncontrast - A2017
CT arthrography of adhesive capsulitis of the shoulder: Are MR signs applicable?
Milena Cernya, Patrick Omoumia, Ahmed Larbi, Daniel Manicourt, Anne Perozziello, Frédéric Lecouvet, Bruno Vande Berg, B…This retrospective study investigated whether signs of adhesive capsulitis (frozen shoulder) typically seen on MRI could also be identified using CT arthrography (CTA). Researchers compared CTA scans from 22 patients wi…
frozen shoulderAdhesive capsulitisArthrographyRotator intervalCTA - A+2017
The Effect of Menstrual Cycle and Contraceptives on ACL Injuries and Laxity
Simone D Herzberg, Makalapua L Motu’apuaka, William Lambert, Rongwei Fu, Jacqueline Brady, Jeanne-Marie GuiseThis systematic review and meta-analysis investigated the relationship between the menstrual cycle, hormonal contraceptives, and the risk of anterior cruciate ligament (ACL) injuries. The researchers found that knee lig…
anterior cruciate ligament; knee injury; hormonal contraceptives; female; human; menstrual cycle; systematic review; meta-analysis; sports medicine - C2017
Hypermobile Ehlers–Danlos Syndrome (a.k.a. Ehlers–Danlos Syndrome Type III and Ehlers–Danlos Syndrome Hypermobility Type): Clinical Description and Natural History
Brad Tinkle, Marco Castori, Britta Berglund, Helen Cohen, Rodney Grahame, Hanadi Kazkaz, Howard LevyThis 2017 review summarizes the clinical understanding of hypermobile Ehlers-Danlos syndrome (hEDS), thought to be the most common hereditary disorder of connective tissue. It is primarily characterized by musculoskelet…
joint hypermobilityjoint hypermobility syndromeEhlers–Danlos syndrome type IIEhlers–Danlos syndrome hypermobility type - A+2017
Effects of vitamin C supplementation on glycaemic control: a systematic review and meta-analysis of randomised controlled trials
A W Ashor, A D Werner, J Lara, N D Willis, J C Mathers, M SiervoThis systematic review and meta-analysis compiled data from 22 randomized controlled trials to assess the effect of vitamin C supplementation on glycemic control. Overall, the researchers found no significant effect on…
Vitamin Cinsulin resistensglycaemic control - A2017
Calcium Signaling in Interstitial Cells: Focus on Telocytes
Beatrice Mihaela Radu, Adela Banciu, Daniel Dumitru Banciu, Mihai Radu, Dragos Cretoiu, Sanda Maria CretoiuThis narrative review describes current knowledge on calcium signaling in a group of cells called interstitial cells, with a special focus on telocytes. These cells and their calcium signals are important for generating…
telocytesinterstitial cellscalcium signalingCa2+ oscillationspacemaker activity - B2017
Cellulite: a review with a focus on subcision
Daniel P Friedmann, Garrett Lane Vick, Vineet MishraThis narrative review examines cellulite, a common skin condition characterized by altered skin topography that primarily affects women on their buttocks and thighs. The authors discuss the potential underlying causes a…
gynoid lipodystrophyfibrous septaeradiofrequencyvacuum-assisted subscision - A2017
Piezoelectric material – A promising approach for bone and cartilage regeneration
Namdev More, Govinda KapusettiThis paper outlines a novel hypothesis for regenerating bone and cartilage, two weight-bearing tissues that are challenging to repair. Current treatments for damage from trauma or diseases like osteoarthritis have signi…
tissue engineeringPiezoelectricityBone regenerationCartilage regeneration - A2017
Vitamin C for preventing atrial fibrillation in high risk patients: a systematic review and meta-analysis
Harri Hemilä, Timo SuonsyrjäThis systematic review and meta-analysis examined 15 trials to see if vitamin C could prevent atrial fibrillation in high-risk patients. The analysis, involving over 2000 subjects, found inconsistent results depending o…
Ascorbic acidantioxidantArrhythmiaAtrial fibrillationCardiac surgery - A2017
We are operating too much
Nicola MaffulliIn this editorial, the author, an orthopedic and trauma surgeon, observes a rising number of operations for orthopedic and trauma ailments. He notes that this trend runs counter to the results of high-quality studies, w…
Surgery - A++2017
Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes
Anitra C Carr, Patrice C Rosengrave, Simone Bayer, Steve Chambers, Jan Mehrtens, Geoff M ShawThis study investigated vitamin C levels in 44 critically ill patients in an intensive care unit (ICU). Researchers found that most patients had low vitamin C levels (hypovitaminosis C), and one-third were severely defi…
Vitamin CsepsisIntensive careHypovitaminosis CCritical illness - A2017
Molecular insights into prolyl and lysyl hydroxylation of fibrillar collagens in health and disease
Rutger A F Gjaltema, Ruud A BankThis narrative review provides an updated overview of the complex process of creating mature collagen. The formation of collagen fibrils from precursor molecules involves many enzymes and chaperones in a series of steps…
Bruck syndrome; Collagen; Ehlers–Danlos syndrome; connective tissue disorders; fibrosis; lysyl hydroxylation; osteogenesis imperfecta; prolyl hydroxylation.