Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2017
The significance of closed kinematic chains to biological movement and dynamic stability
Stephen Levin, Susan Lowell de Sol!orzano, Graham ScarrBiomechanical research has long focused on the body as a system of levers, but this review highlights the importance of "closed kinematic chains" (CKCs). These are continuous mechanical loops that couple multiple parts…
biotensegrityBiomechanicsClosed-chainDevelopmentEvolution - A++2017
EFFECT OF MATRIX RHYTHM THERAPY (MRT) COMBINED WITH PHYSIOTHERAPY INTERVENTION IN FROZEN SHOULDER – A CASE REPORT
Vijay Bhartiya, Shrikant Darade, Sandip Bhagwat, Manjumala RoyThis case report describes the treatment of a 52-year-old man with a painful and stiff right shoulder, diagnosed as frozen shoulder. His condition also involved tendinosis, bursitis, and osteoarthritic changes. The pati…
exercisesfrozen shoulderMRT - C2017
Bi component T1p and T2 Relaxation Mapping of Skeletal Muscle In-Vivo
Azadeh Sharafi, Gregory Chang, Ravinder R RegatteResearchers evaluated a specific MRI technique for creating more detailed images of skeletal muscle. Using what is known as T1ρ and T2 relaxation mapping on the calf muscles of healthy volunteers, they were able to dist…
inflammationfibrosisskeletal musclebi-componentT2 relaxation - A++2017
Vitamin C and Immune Function
Anitra C Carr, Silvia MagginiThis narrative review explores the crucial role of Vitamin C in the human immune system. As a potent antioxidant, it supports various functions in both the innate and adaptive immune responses, from strengthening the sk…
ascorbate; ascorbic acid; immunity; immune system; neutrophil function; microbial killing; lymphocytes; infection; vitamin C - A++2017
Massage therapy research review
Tiffany FieldThis review summarizes research showing beneficial effects of massage therapy for a wide range of conditions, including prenatal depression, pain syndromes, autoimmune conditions, and issues related to aging. The author…
Massage therapy research review - A++2017
NAD and the aging process: Role in life, death and everything in between
Claudia C S Chini, Mariana G Tarragó, Eduardo N ChiniThis narrative review explores the vital role of the molecule NAD in cellular health and the aging process. Beyond its traditional role in metabolism, NAD is essential for cell signaling and regulating the epigenetic st…
Aging; CD38; Mitochondrial function; NAD(+); PARP; SIRTUINS - B2017
Mechanical Properties of the Cytoskeleton and Cells
A F Pegoraro, P Janmey, D A WeitzIn this review article, the authors describe the cytoskeleton, which is the cell's main mechanical structure. It is a complex and dynamic network of biopolymers that includes microtubules, actin, and intermediate filame…
cytoskeletonmicrotubulesactin filamentintermediate filament - A2017
Does the vaginal wall become thinner as prolapse grade increases?
Rhiannon Bray, Alex Derpapas, Ruwan Fernando, Vik Khullar, Demetri C PanayiThis study investigated the relationship between vaginal wall thickness and the severity of pelvic organ prolapse. Researchers used ultrasound to measure the vaginal walls of 243 women with symptomatic prolapse. They fo…
Prolapse . Ultrasonography . Vaginal wall thickness - A+++2017
Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation
Benoit Chassaing, Tom Van de Wiele, Jana De Bodt, Massimo Marzorati, Andrew T GewirtzThis study investigated how common food additives, specifically the emulsifiers polysorbate 80 (P80) and carboxymethylcellulose (CMC), affect the gut microbiota. Using a laboratory model of the human intestinal ecosyste…
INFLAMMATION; INTESTINAL MICROBIOLOGY - B2017
Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis
Hsin-Ying Huang, Ana Rivas-Caicedo, François Renevey, Hélène Cannelle, Elisa Peranzoni, Leonardo Scarpellino, Debbie L…This study investigated how antibody-producing plasma cells are supported within lymph nodes. Researchers identified a specific type of connective tissue cell, a medullary fibroblastic reticular cell (FRC), that forms a…
FRC subsetslymph node medullaextrafollicular B cell differentiationplasma cell survivalhumoral response - A2017
The myodural bridge existing in the Nephocaena phocaenoides
Pei Liu, Chan Li, Nan Zheng, Qiang Xu, Sheng-Bo Yu, Hong-Jin SuiThe myodural bridge is a connection between a small neck muscle and the spinal cord's outer covering (the dura mater) previously identified in humans. In this anatomical animal study, researchers investigated whether a…
dura materMyodural Bridge - A+++2017
Vitamin C Status Correlates with Markers of Metabolic and Cognitive Health in 50-Year-Olds: Findings of the CHALICE Cohort Study
John F Pearson, Juliet M Pullar, Renee Wilson, Janet K Spittlehouse, Margreet C M Vissers, Paula M L Skidmore, Jinny Wi…This cohort study examined vitamin C status in 404 fifty-year-olds in New Zealand. Researchers measured the concentration of vitamin C in participants' blood plasma as well as their dietary intake. The results showed th…
ascorbate; cognition; HbA1c; insulin; glucose; hypovitaminosis C