Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2018
Resveratrol: A Double-Edged Sword in Health Benefits
Bahare Salehi, Abhay Prakash Mishra, Manisha Nigam, Bilge Sener, Mehtap Kilic, Mehdi Sharifi-Rad, Patrick Valere Tsouh…This narrative review explores resveratrol, a natural polyphenol found in grape skins, red wine, and various plants. Research suggests that this compound possesses significant antioxidant, anti-inflammatory, and cardiop…
anticancer; antimicrobial; antioxidant; pharmacological activity; physiological effects; resveratrol. - A2018
Variations in Contents of Hyaluronan in the Peritumoral Micro-Environment of Human Chondrosarcoma
Caterina Fede, Carla Stecco, Andrea Angelini, Chenglei Fan, Elisa Belluzzi, Assunta Pozzuoli, Pietro Ruggieri, Raffaele…The micro-environment surrounding a tumor greatly influences its growth and response to therapy. This study focused on chondrosarcoma, a type of bone cancer resistant to both chemotherapy and radiation. Researchers quan…
hyaluronan; chondrosarcoma; peritumoral stroma; fascia; tumor micro-environment; malignant bone tumor; grade - A2018
Immediate effects of self-myofascial release on latent trigger point sensitivity: a randomized, placebo-controlled trial
Jan Wilke, Lutz Vogt, Winfried BanzerThis randomized, placebo-controlled trial examined whether foam rolling could immediately reduce sensitivity in latent trigger points. Researchers compared 90 seconds of static compression, dynamic rolling, and a placeb…
fasciaMyofascial painFoam rollingSelf-masage - A+++2018
Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study
Do-Un Kim, Hee-Chul Chung, Jia Choi, Yasuo Sakai, Boo-Yong LeeThis randomized, double-blind, placebo-controlled study evaluated the effects of daily low-molecular-weight collagen peptide (LMWCP) supplementation on the skin of 64 women. Over 12 weeks, researchers measured skin hydr…
collagen hydrolysate; collagen tripeptide; fish collagen; low-molecular-weight collagen peptide; photoaging; skin elasticity; skin hydration; skin wrinkling; type I collagen. - A2018
Effectiveness of 3-dimensional shoulder ultrasound in the diagnosis of rotator cuff tears
Aiping Teng, Fanxiao Liu, Dongsheng Zhou, Tao He, Yan Chevalier, Roland M KlarIn this meta-analysis, researchers combined data from seven studies involving 282 patients to evaluate the effectiveness of 3-dimensional (3D) ultrasound in diagnosing rotator cuff tears. The analysis found that 3D ultr…
3-dimensional ultrasounddiagnostic valuemeta-analysisrotator cuff tears - A+++2018
Low-Intensity Vibration Improves Muscle Healing in a Mouse Model of Laceration Injury
Thomas F Corbiere, Eileen M Weinheimer-Haus, Stefan Judex, Timothy J KohIn this animal study, researchers investigated if low-intensity vibration (LIV) could improve healing of lacerated calf muscles in mice. The mice were divided into groups that received daily vibration treatment and a co…
skeletal muscle injury; laceration; low-intensity vibration; muscle regeneration; fibrosis - A+++2018
Anatomical and Functional Relationships Between External Abdominal Oblique Muscle and Posterior Layer of Thoracolumbar Fascia
Chenglei Fan, Caterina Fede, Nathaly Gaudreault, Andrea Porzionato, Veronica Macchi, Raffaele de Caro, Carla SteccoThis study investigated the anatomical connection between the external abdominal oblique muscle (EO) and the thoracolumbar fascia (TLF) in the low back. Using both cadaveric dissection and CT scans, researchers found a…
external abdominal oblique muscle; fascia; lumbar; computed tomography - A2018
Lipedema—An update
Uwe WollinaThis review provides an update on lipedema, a chronic condition affecting subcutaneous fat tissue in the limbs, almost exclusively in women. It typically appears during or after puberty and is characterized by symmetric…
painEdemaobesitylipedemalymphedema - 1A+++2018
Emission of Biophotons and Adjustable Sounds by the Fascial System: Review and Reflections for Manual Therapy
Bruno Bordoni, F Marelli, B Morabito, B SacconiIn this narrative review, the authors explore how fascia, the web of connective tissue enveloping everything in the body, might communicate. They discuss research suggesting the fascial system may emit faint light parti…
fasciaMuscleManual TherapyMyofascialOsteopathic - A+2018
Negative Air Ions and Their Effects on Human Health and Air Quality Improvement
Shu-Ye Jiang, Ali Ma, Srinivasan RamachandranThis review paper examines the research on negative air ions (NAIs) and their effects on human health and air quality. Used for over a century in air cleaning, NAIs are associated with improved psychological health and…
negative air ions; superoxide; particulate matter; pulsed electric field - A2018
Orientation and property of fibers of the myodural bridge in humans
Nan Zheng, Yan-Yan Chi, Xiao-Han Yang, Nan-Xing Wang, Yi-Lin Li, Yang-Yang Ge, Lan-Xin Zhang, Tai-Yuan Liu, Xiao-Ying Y…The myodural bridge is a fibrous connection between the deep suboccipital muscles of the neck and the spinal dura mater, the tough outer covering of the spinal cord. In this anatomical study, researchers investigated th…
Atlanto-axial interspace; Atlanto-occipital interspace; Collagen I fibers; Histologic staining; Myodural bridge; Suboccipital muscles; Vertebral dural ligament - A+++2018
Effects of Plantar Vibration on Bone and Deep Fascia in a Rat Hindlimb Unloading Model of Disuse
Yunfei Huang, Yubo Fan, Michele Salanova, Xiao Yang, Lianwen Sun, Dieter BlottnerThis animal study investigated how disuse affects deep fascia and bone, and whether vibration could counteract these effects. Researchers used a rat model where hindlimbs were unloaded for 21 days to simulate disuse, wh…
extracellular matrixcollagenBonedeep fasciaBiomechanics