Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2018
Fractal fluctuations in muscular activity contribute to judgments of length but not heaviness via dynamic touch
Madhur Mangalam, James D Conners, Damian G Kelty-Stephen, Tarkeshwar SinghCOPD (Chronic Obstructive Pulmonary Disease) is a progressive condition that often involves chest pain. This article analyzes the possible causes of this pain, focusing on a less frequently considered source: the fascia…
Biotensegrity · Effortful touch · Fractality · Haptic perception · Multifractality · Muscular effort · Perceptual invariance · Psychophysics - A+++2018
The laterality of the gallop gait in Thoroughbred racehorses
Paulette Cully, Brian Nielsen, Bryony Lancaster, Jessica Martin, Paul McGreevyThis observational study investigated whether Thoroughbred racehorses have a preferred leading leg when transitioning from a halt to a gallop in starting stalls. Analyzing over 2,000 horses, researchers found no overall…
asymmetryrace horses - B2018
Effectiveness of sodium bicarbonate infusion on mortality in septic patients with metabolic acidosis
Zhongheng Zhang, Carlie Zhu, Lei Mo, Yucai HongThis retrospective database study investigated whether sodium bicarbonate infusion affected mortality in septic patients with metabolic acidosis. The researchers found no overall survival benefit in the general populati…
sepsiscritical careSodium bicarbonateMortalityMarginal structural Cox - A2018
A New Concept of Biotensegrity Incorporating Liquid Tissues: Blood and Lymph
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Roberto CastagnaThis conceptual article proposes an update to the biotensegrity model, which traditionally focuses on the solid structures of the fascial system. The authors argue that "liquid tissues" like blood and lymph should also…
fasciaChiropracticManual TherapyMyofascialOsteopathic - A2018
The myodural bridges’ existence in the sperm whale
Pei Liu, Chan Li, Nan Zheng, Xiaoying Yuan, Yutong Zhou, Pu Chun, Yanyan Chi, Campbell Gilmore, Shengbo Yu, Hongjin SuiIn this anatomical animal study, researchers examined tissue from a sperm whale to see if it possessed a myodural bridge, a connection between the neck muscles and the dura mater previously identified in humans. The inv…
Myodural Bridge - A2018
Hyaluronan in adipogenesis, adipose tissue physiology and systemic metabolism
Yi Zhu, llja L Kruglikov, Yucel Akgul, Philipp E SchererThis narrative review summarizes research on hyaluronic acid (HA), a sugar molecule abundant in the body's extracellular matrix. The functions of HA are largely dictated by its molecular size, and it is commonly used as…
HA - A2018
Muscle spindles of the rat sternomastoid muscle
Walter Giuriati, Barbara Ravara, Andrea Porzionato, Giovanna Albertin, Carla Stecco, Veronica Macchi, Raffaele De Caro,…This animal study on rats examined the sternomastoid muscle in the neck, which has a unique structure. Researchers found it has two distinct regions: a superficial "white" part with fast-twitch fibers and a deep "red" p…
ratsternomastoid musclemuscle spindlesfiber typestranslational studies - A2018
Lipedema—An update
Uwe WollinaThis review provides an update on lipedema, a chronic condition affecting subcutaneous fat tissue in the limbs, almost exclusively in women. It typically appears during or after puberty and is characterized by symmetric…
painEdemaobesitylipedemalymphedema - B2018
The Receptor for Hyaluronan- Mediated Motility (CD168) promotes inflammation and fibrosis after acute lung injury
Zheng Cui, Jie Liao, Naeun Cheongb, Christopher Longoria, Gaoyuan Cao, Horace M DeLisser, Rashmin C SavaniIn this animal study, researchers investigated the role of a specific receptor, RHAMM, in the body's response to acute lung injury. Using mouse models, they compared outcomes in mice that lacked the RHAMM receptor to th…
HA - 1A+2018
The Fasciacytes- A New Cell Devoted To Fascial Gliding Regulation
Carla Stecco, Caterina Fede, Veronica Macchi, Andrea Porzionato, Lucia Petrelli, Carlo Biz, Robert Stern, Raffaele De C…Researchers have identified a new type of cell within fascia, which they have named "fasciacytes." This study presents evidence that these specialized cells are responsible for producing hyaluronan, a key component of t…
hyaluronanfasciafasciacytesextracellular matrix - A2018
Morphological evidence of telocytes in human synovium
Irene Rosa, Mirca Marini, Daniele Guasti, Lidia Ibba-Manneschi, Mirko ManettiA relatively new type of cell, called a telocyte, has been found in many human tissues. This study was the first to look for and find these cells in the synovial membrane, which is the lining of our movable joints. Usin…
telocytessynovium - A+2018
Endogenous systems involved in exercise-induced analgesia
R DA SILVA SANTOS, G GALDINOThis narrative review describes the phenomenon of exercise-induced analgesia, which is the pain-relieving effect of physical activity. Studied since the 1970s, this effect is seen in both endurance and resistance exerci…
EndocannabinoidspainexerciseNitric oxideanalgesia
