Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2018
Treatment for cellulite
Neil SadickThis brief review summarizes the scientific evidence for various treatments for cellulite, a condition present in 80% to 90% of post-pubertal women. The author examines the safety and efficacy of methods ranging from to…
Cellulite pathophysiology adipocytes radiofrequency lasers - A++2018
Various stem cells in acupuncture meridians and points and their putative roles
Jeanne Adiwinata PawitanThis narrative review explores the connection between acupuncture points and an anatomical network known as the Primo Vascular System (PVS). Formerly called the Bong-Han system, the PVS consists of microscopic vessels a…
Bong-Han system; Kyungrak system; Primo microcell; Primo node; Primo vascular system; Primo vessel; Stem cell. - A+++2018
Resveratrol: A Double-Edged Sword in Health Benefits
Bahare Salehi, Abhay Prakash Mishra, Manisha Nigam, Bilge Sener, Mehtap Kilic, Mehdi Sharifi-Rad, Patrick Valere Tsouh…This narrative review explores resveratrol, a natural polyphenol found in grape skins, red wine, and various plants. Research suggests that this compound possesses significant antioxidant, anti-inflammatory, and cardiop…
anticancer; antimicrobial; antioxidant; pharmacological activity; physiological effects; resveratrol. - A2018
Fasciae of the musculoskeletal system: normal anatomy and MR patterns of involvement in autoimmune diseases
Thomas Kirchgesner, Xavier Demondion, Maria Stoenoiu, Patrick Durez, Adrien Nzeusseu Toukap, Frédéric Houssiau, Christi…This review article describes the fascial system as a three-dimensional continuum of connective tissue found throughout the body. The authors review the normal anatomy of fascia and its appearance on magnetic resonance…
fasciaMusculoskeletalAnatomyAutoimmuneMRI - A+++2018
Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis
Jing LiThis commentary presents a meta-analysis of research on using vitamin C to treat sepsis. It builds upon two previous reviews by pooling their data for a combined statistical analysis. The aggregated results indicated a…
meta-analysisVitamin CAscorbic acidsepsisSevere sepsis - A2018
Neuroinflammation and central sensitization in chronic and widespread pain
Ru-Rong Ji, Andrea Nackley, Yul Huh, Niccolò Terrando, William MaixnerChronic pain is partly maintained by central sensitization, a state where the nervous system becomes hypersensitive. This review discusses how neuroinflammation—inflammation in the nervous system—contributes to this pro…
inflammationchronic paainneuroinflammationsensitization - A+++2018
The laterality of the gallop gait in Thoroughbred racehorses
Paulette Cully, Brian Nielsen, Bryony Lancaster, Jessica Martin, Paul McGreevyThis observational study investigated whether Thoroughbred racehorses have a preferred leading leg when transitioning from a halt to a gallop in starting stalls. Analyzing over 2,000 horses, researchers found no overall…
asymmetryrace horses - A++2018
Low intensity vibration increases cartilage thickness in obese mice
Tee Pamon, Vincent Bhandal, Benjamin J Adler, M Ete Chan, Clinton T RubinThis animal study investigated if a high-fat diet affected cartilage thickness in mice and if low-intensity vibration (LIV) could offer protection. Contrary to expectations, the high-fat diet alone did not significantly…
osteoarthritis; chondrocytes; exercise; biomechanics; adaptation; stem cell - 1A+2018
Effect of Stretching on Thoracolumbar Fascia Injury and Movement Restriction in a Porcine Model
H M Langevin, J Bishop, R Maple, G J Badger, J R FoxIn this animal study on pigs, researchers investigated the effect of stretching on the thoracolumbar fascia after injury and movement restriction. An injury combined with restricted movement led to reduced fascial mobil…
fasciaConnective tissueStretchingManual TherapyMovement Therapy - A+++2018
Applied Myo-Fascial Advances in Veterinary Medicine and Practice
A P Harrison, V S ElbrøndThis review article summarizes recent advances in veterinary medicine with a focus on myofascia. It presents findings on the structure and function of these interconnected tissues, highlighting the benefits of treating…
acoustic myography; kinetic lines; bioimpedance; acupuncture; release therapy - A+++2018
Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study
Do-Un Kim, Hee-Chul Chung, Jia Choi, Yasuo Sakai, Boo-Yong LeeThis randomized, double-blind, placebo-controlled study evaluated the effects of daily low-molecular-weight collagen peptide (LMWCP) supplementation on the skin of 64 women. Over 12 weeks, researchers measured skin hydr…
collagen hydrolysate; collagen tripeptide; fish collagen; low-molecular-weight collagen peptide; photoaging; skin elasticity; skin hydration; skin wrinkling; type I collagen. - A2018
Pathobiology of cigarette smoke-induced invasive cancer of the renal pelvis and its prevention by vitamin C
Shinjini Ganguly, Ayan Chandra, Indu B ChatterjeeIn this animal study, researchers investigated how cigarette smoke might cause invasive cancer of the renal pelvis and if vitamin C could offer protection. They found that when guinea pigs were exposed to cigarette smok…
Invasive cancer of the renal pelvis Cigarette smoke Vitamin C Oxidative damage Persistent EGFR signaling Cell cycle deregulation
