Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies

2,806

studies

602

top-graded

2,783

with plain-language summary

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Showing 385–396 of 1,127 studies · page 33/94With summary

A
2019
Role of matrix metalloproteinases 2 and 9 in the development of frozen shoulder: human data and experimental analysis in a rat contracture model
Chul-Hyun Cho, Yun-Mee Lho, Ilseon Hwang, Du Hwan Kim
This study investigated the biological processes behind frozen shoulder, a condition characterized by pain and stiffness. Researchers analyzed joint capsule tissue from both patients with frozen shoulder and from a rat…
inflammationfibrosisfrozen shoulderimmobilizationrat; matrix metalloproteinases
A+++
2019
New Insights of Uterine Leiomyoma Pathogenesis: Endocannabinoid System
Thangesweran Ayakannu, Anthony H Taylor, Timothy H Marczylo, Justin C Konje
This study investigated the role of the endocannabinoid system in the development of uterine leiomyomas, commonly known as fibroids. Researchers analyzed tissue samples and found that the expression of specific receptor…
CannabinoidsCannabinoid receptorsuterine myomfibroids
A++
2019
8 natural supplements to help fight inflammation
Zawn Villines
Inflammation is a natural response to injury or infection, but when it becomes chronic, it can lead to long-term pain and tissue damage. This article reviews several natural supplements that may help the body manage chr…
inflammationomega-3curcumin
A
2019
3D volumetric MR arthrographic assessment of shoulder joint capacity in patients with primary adhesive capsulitis
Hayri Ogul, Nurmuhammet Tas, Kutsi Tuncer, Gokhan Polat, Yasemin Ogul, Berhan Pirimoglu, Mecit Kantarci
This study used 3D MR arthrography to measure and compare shoulder joint volume in patients with primary adhesive capsulitis (frozen shoulder) against a healthy control group. Researchers found that the patient group ha…
frozen shoulderAdhesive capsulitisMR arthrography
A++
2019
Effects of Different Vitamin C–Enriched Collagen Derivatives on Collagen Synthesis
Dana M Lis, Keith Baar
This study investigated how three different forms of vitamin C-enriched collagen supplements affected markers of collagen synthesis in ten active men. Participants consumed either gelatin, hydrolyzed collagen, a gummy v…
MusculoskeletalexercisegelatinN-terminal peptide of procollageninjury
A
2018
Fascial well-being: Mechanotransduction in manual and movement therapies
Leon Chaitow
This article discusses mechanotransduction, the process by which cells in connective tissue sense and respond to mechanical forces like stretch, compression, and shear. Specialized cells such as fibroblasts communicate…
mechanotransduction
1A+
2018
The Equine Hindlimb Proximal Suspensory Ligament: an Assessment of Health and Function by Means of Its Damping Harmonic Oscillator Properties, Measured Using an Acoustic Myography System: a New Modality Study
Jillian Costello Chavers, A Kent Allen, Waqas Ahmed, Lene Høeg Fuglsang-Damgaard, Adrian P Harrison
This study in horses explored a new method called acoustic myography (AMG) to help diagnose injuries in the proximal suspensory ligament (PSL) of the hindlimb. Researchers used a device to record sound signals from the…
equineCUROAcoustic myographySuspensory desmitisLameness
A++
2018
Female hormones: do they influence muscle and tendon protein metabolism?
Mette Hansen
This narrative review examines how female sex hormones, particularly estrogen, influence the metabolism of proteins in muscles and tendons. After menopause, declining hormone levels are associated with accelerated muscl…
ACL anterior cruciate ligament; ER oestrogen receptors; ERT oestrogen replacement therapy; HRT hormone replacement therapy; IGF-I insulin-like growth factor-I; OC oral contraceptive; Collagen; Hormone replacement therapy; Muscle strength; Oestrogen; Sarcopenia.
A+++
2018
Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis
Jing Li
This commentary presents a meta-analysis of research on using vitamin C to treat sepsis. It builds upon two previous reviews by pooling their data for a combined statistical analysis. The aggregated results indicated a…
meta-analysisVitamin CAscorbic acidsepsisSevere sepsis
1A+
2018
From mechanobiology to developmentally inspired engineering
Donald Ingber
This review article, based on a lecture, explores the field of mechanobiology, which studies the central role of physical forces in development and physiology. The author reviews 40 years of his laboratory's foundationa…
Tensegritymechanicalorgans-on-chipstissue engineering
A
2018
Fascial preadipocytes: another missing piece of the puzzle to understand fibromyalgia?
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Francesca Cavallaro, David Lintonbon
In this review paper, the authors discuss fibromyalgia, a chronic pain condition whose cause remains uncertain. While often linked to changes in the central nervous system, research also points to peripheral nerve damag…
fasciaFibromyalgiapainMyofascialneuropathic pain
A
2018
Biotensegrity and myofascial chains: A global approach to an integrated kinetic chain
S L Dischiavi, A A Wright, E J Hegedus, C M Bleakley
This theoretical paper proposes a holistic way to understand human movement, contrasting it with the traditional approach of studying body parts in isolation. The authors suggest a model based on "biotensegrity," where…
RehabilitationbiotensegrityMuscular chainsDynamic knee valgusHip