Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2019
The Stomach’s Communication with Its Related Acupoints, and the “Intelligent Tissue” Hypothesis
Fletcher KovichThis study explores the "intelligent tissue" hypothesis, which suggests that an organ's functional state is reflected in real-time at specific acupuncture points. By monitoring electrical impedance at six stomach-relate…
acupunctureimpedanceduodenalpacesetterslow wave - A++2019
Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory
Ramesh C Gupta, Rajiv Lall, Ajay Srivastava, Anita SinhaThis narrative review explores hyaluronic acid (HA), a naturally occurring substance found in connective tissues and synovial fluid. HA is essential for joint lubrication and viscoelasticity, but its concentration and m…
hyaluronanwound healingHyaluronic acidosteoarthritiscancer therapy - A+2019
Effect of breakfast on weight and energy intake: systematic review and meta-analysis of randomised controlled trials
Katherine Sievert, Sultana Monira Hussain, Matthew J Page, Yuanyuan Wang, Harrison J Hughes, Mary Malek, Flavia M Cicut…This systematic review and meta-analysis examined whether regular breakfast consumption affects body weight and energy intake in adults from high-income countries. The findings suggest that individuals who skipped break…
beakfastweight control - A+++2019
Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology
Priya Rangan, Inyoung Choi, MinWei, Gerardo Navarrete, Esra Guen, Sebastian Brandhorst, Nobel Enyati, Gab Pasia, Daral…This study investigates how cycles of a fasting-mimicking diet (FMD) affect inflammatory bowel disease (IBD) in both mice and humans. In animal models, FMD cycles reduced intestinal inflammation, encouraged the growth o…
Crohn’s disease; fasting; fasting-mimicking diet; gut microbiota; inflammation; inflammatory bowel disease; intermittent fasting; microbiome; ulcerative colitis - A+++2019
Fermented Foods: Definitions and Characteristics, Impact on the Gut Microbiota and Effects on Gastrointestinal Health and Disease
Eirini Dimidi, Selina Rose Cox, Megan Rossi, Kevin WhelanThis narrative review examines how fermented foods such as kefir, kombucha, and sourdough bread affect gut health and the microbiota. The authors describe how the fermentation process creates bioactive compounds and pot…
fermented food; kefir; kimchi; kombucha; miso; natto; sauerkraut; sourdough; soy; tempeh - A++2018
Ascorbic acid in cancer treatment: let the phoenix fly
Niraj Shenoy, Edward Creagan, Thomas Witzig, Mark LevineThis review article discusses the renewed interest in Vitamin C (ascorbic acid) as a potential anti-cancer agent. When administered intravenously, Vitamin C can reach much higher concentrations in the body than when tak…
cancerVitamin Cascorbatepharmacokinetics - A+2018
Bone turnover markers after the menopause: T-score approach
Fatma Gossiel, Hibatallah Altaher, David M Reid, Christian Roux, Dieter Felsenberg, Claus-C Glüer, Richard EastellThis study investigated how bone turnover changes in women before and after menopause by measuring specific markers for bone formation (PINP) and bone resorption (CTX). The researchers found that bone turnover increases…
Bone mineral density; Bone turnover markers; Menopause; Osteoporosis - A2018
Hyaluronan in adipogenesis, adipose tissue physiology and systemic metabolism
Yi Zhu, llja L Kruglikov, Yucel Akgul, Philipp E SchererThis narrative review summarizes research on hyaluronic acid (HA), a sugar molecule abundant in the body's extracellular matrix. The functions of HA are largely dictated by its molecular size, and it is commonly used as…
HA - 1A+2018
From mechanobiology to developmentally inspired engineering
Donald IngberThis review article, based on a lecture, explores the field of mechanobiology, which studies the central role of physical forces in development and physiology. The author reviews 40 years of his laboratory's foundationa…
Tensegritymechanicalorgans-on-chipstissue engineering - C2018
Anatomy of the fasciae and fascial spaces of the maxillofacial and the anterior neck regions
Seiichiro KitamuraThis narrative review simplifies the complex anatomy of the fascia in the face, jaw, and front of the neck. The author organizes the region into four distinct portions based on their relationship to a key fascial layer,…
fasciaFascial spaceGross anatomyMaxillofacial regionAnterior neck - A++2018
Release of fascial compartment boundaries reduces muscle force output
Roy J Ruttiman, David A Sleboda,, Thomas J RobertsIn this animal study, researchers investigated how the fascial sheets that enclose muscles affect their function. They surgically removed the fascia from a wing muscle in wild turkeys to see how it changed the muscle's…
Muscletendoncompartmentfasciotomyintramuscular pressure - B2018
The Receptor for Hyaluronan- Mediated Motility (CD168) promotes inflammation and fibrosis after acute lung injury
Zheng Cui, Jie Liao, Naeun Cheongb, Christopher Longoria, Gaoyuan Cao, Horace M DeLisser, Rashmin C SavaniIn this animal study, researchers investigated the role of a specific receptor, RHAMM, in the body's response to acute lung injury. Using mouse models, they compared outcomes in mice that lacked the RHAMM receptor to th…
HA