Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2019
Mechanobiology of cells and cell systems, such as organoids
Ece Bayir, Aylin Sendemir, Yannis F MissirlisThis review discusses organoids, which are three-dimensional tissues grown in a lab that self-organize to mimic organ development. While organoids offer great potential for disease modeling and drug development, little…
mechanotransductionmechanobiologyOrganoidMechanoepigeneticsCollective cell behavior - A++2019
Inter and Intra operator reliability of motor and palpation evaluation in fascial manipulation in individuals coxarthrosis
Andrea Cotti, Massimiliano Del Corso, Roberto Diana, Luigi Cornale, Alessandra Sudanese, Antonio Stecco, Mirco BranchiniThis study investigated the reliability of assessment methods used in Fascial Manipulation® (FM®) for individuals with hip osteoarthritis (coxarthrosis). Researchers tested whether different therapists, and the same the…
Fascial manipulation; Inter reliability; intra reliability; movement evaluation; motor evaluation; palpation evaluation; coxarthrosis; pain - A++2019
Mechanics and structural stability of the collagen triple helix
Michael W H Kirkness, Kathrin Lehmann, Nancy R FordeThis narrative review explores the mechanical properties of collagen, the body's primary structural protein. Collagen's unique triple helix structure is believed to be the source of its stability and resilience in tissu…
collagentriple helix - A++2019
Effects of Different Vitamin C–Enriched Collagen Derivatives on Collagen Synthesis
Dana M Lis, Keith BaarThis study investigated how three different forms of vitamin C-enriched collagen supplements affected markers of collagen synthesis in ten active men. Participants consumed either gelatin, hydrolyzed collagen, a gummy v…
MusculoskeletalexercisegelatinN-terminal peptide of procollageninjury - B2019
Photo-crosslinked gelatin-hyaluronic acid methacrylate hydrogel-committed nucleus pulposus-like differentiation of adipose stromal cells for intervertebral disc repair
Pengfei Chen, Lei Ning, Pengcheng Qiu, Jian Mo, Sheng Mei, Chen Xia, Jianfeng Zhang, Xianfeng Lin, Shunwu FanThis animal study on rats investigated a new strategy for repairing degenerated intervertebral discs using stem cells. Researchers combined adipose-derived stromal cells (ASCs) with a special light-activated hydrogel ma…
IntegrinsmicroenvironmentHydrogeladipose stem cellscellular proliferation - A++2019
Plasma Amino Acid Concentrations After the Ingestion of Dairy and Collagen Proteins, in Healthy Active Males
Rebekah D Alcock, Gregory C Shaw, Nicolin Tee, Louise M BurkeThis study investigated how blood amino acid levels changed in healthy, active men after they consumed either collagen or dairy proteins. Researchers found that the different protein sources led to distinct amino acid p…
Connective tissuetendonligamentprolineleucine - B2019
TMEM2: a missing link in hyaluronan catabolism identified?
Yu Yamaguchi, Hayato Yamamoto, Yuki Tobisawa, Fumitoshi IrieHyaluronan (HA) is a large molecule in our connective tissues that is broken down and replaced very quickly. Scientists have long understood that large HA molecules are first chopped into smaller pieces on the surface o…
hyaluronanhyaluronidaseTMEM2HA catabolism - A2019
Age-related changes in leg proprioception: implications for postural control
Mélanie Henry, Stéphane BaudryThis narrative review examines how aging affects proprioception—the body's sense of its own position and movement—and its implications for balance. To maintain an upright stance, the brain relies on signals from recepto…
proprioceptionmuscle spindlesbalanceIa afferentsupright standing - A2019
The effects of vibration-induced altered stretch reflex sensitivity on maximal motor unit firing properties
Alejandra Barrera-Curiel, Ryan J Colquhoun, Jesus A Hernandez-Sarabia, Jason M DeFreitasResearchers investigated how muscle vibration, which affects the stretch reflex, influences muscle strength and nerve signals during maximal effort. In a study with 24 participants performing maximal knee extensions, th…
group Ia afferents; muscle spindle function; muscle vibration - A++2019
Role of the immune system in vascular function and blood pressure control induced by faecal microbiota transplantation in rats
Marta Toral, Iñaki Robles Vera, Néstor de la Visitación, Miguel Romero, Manuel Sánchez, Manuel Gómez Guzmán, Alba Rodri…This animal study investigated the link between gut bacteria, the immune system, and blood pressure in rats. Researchers transplanted gut microbiota between spontaneously hypertensive rats and rats with normal blood pre…
hypertensionendothelial dysfunctiongut dysbiosisimmune cells - A++2019
Observation using thermography of post-operative reaction after fascial manipulation®
Joanna Fidut-Wrońska, Kamil Chołuj, Justyna Chmiel, Katarzyna Pikto-Pitkiewicz, Piotr MajcherThis study investigated whether Fascial Manipulation® causes a local increase in skin temperature, which is theorized to be part of its mechanism. Researchers used a thermal-imaging camera to measure skin temperature in…
inflammationFascial manipulationthermography - A++2019
Characterization of bony changes localized to the cervical articular processes in a mixed population of horses
Kevin K Haussler, Roy R Pool, Hilary M ClaytonThis observational cross-sectional study characterized bony changes in the cervical articular processes of 55 horses without primary complaints of neck pain. The researchers found that 72% of the examined joints exhibit…
cervical processes