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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 361–372 of 1,131 studies · page 31/95
A2019

Bone Broth Unlikely to Provide Reliable Concentrations of Collagen Precursors Compared With Supplemental Sources of Collagen Used in Collagen Research

Rebekah D Alcock, Gregory C Shaw, Louise M Burke

This study analyzed the amino acid content of bone broth to assess it as a reliable source of collagen precursors, the building blocks the body uses to make collagen. Researchers compared various broths—commercial, home…

gelatine; glycine; ligament; proline; protein; tendon
A2019

Hierarchical Hydrogel Composite Interfaces with Robust Mechanical Properties for Biomedical Applications

Yuting Zhu, Qiang Zhang, Xiaoli Shi, Dong Han

This review summarizes advances in hydrogel composites, materials designed to mimic the body's extracellular matrix (ECM). Cells naturally sense and respond to the mechanical properties and physical structure of the ECM…

tissue engineeringECMHydrogels
A2019

Trigger Points, Pressure Pain Hyperalgesia, and Mechanosensitivity of Neural Tissue in Women with Chronic Pelvic Pain

Pedro Fuentes-Márquez, Marie Carmen Valenza, Irene Cabrera-Martos, Ana Ríos-Sánchez, Olga Ocón-Hernández

In this case-control study, researchers compared women with chronic pelvic pain to a healthy control group. They found that women with pelvic pain had significantly more myofascial trigger points in their low back, glut…

Myofascial Pain Syndrome; Pressure Algometry; Neurodynamics; Chronic Pelvic Pain
A+2019

Anti-Inflammatory Diets and Fatigue

Ulrike Hass, Catrin Herpich, Kristina Norman

This narrative review explores the link between pro-inflammatory status and chronic disease-related fatigue in conditions such as cancer, fibromyalgia, and chronic fatigue syndrome. While evidence for individual nutrien…

anti-inflammatory nutrition; cancer; chronic fatigue; cytokines; fatigue reduction diet; inflammation; myalgic encephalomyelitis; omega-3 fatty acids; polyphenols; probiotics.
A++2019

Observation using thermography of post-operative reaction after fascial manipulation®

Joanna Fidut-Wrońska, Kamil Chołuj, Justyna Chmiel, Katarzyna Pikto-Pitkiewicz, Piotr Majcher

This study investigated whether Fascial Manipulation® causes a local increase in skin temperature, which is theorized to be part of its mechanism. Researchers used a thermal-imaging camera to measure skin temperature in…

inflammationFascial manipulationthermography
A+++2019

Tentorium Cerebelli: Muscles, Ligaments, and Dura Mater, Part 1

Bruno Bordoni, Marta Simonelli, Maria Marcella Lagana

In this narrative review, the authors describe the anatomy of the tentorium cerebelli, part of the reciprocal tension membranes that divide areas of the brain. They highlight its connections to the dura mater, ligaments…

fasciafascial systemdura mater
A+++2019

Cannabis sativa L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury

Enrico Sangiovanni, Marco Fumagalli, Barbara Pacchetti, Stefano Piazza, Andrea Magnavacca, Saba Khalilpour, Gloria Melz…

This in vitro study investigated how Cannabis sativa extract and its component cannabidiol (CBD) affect inflammation in human skin cells. Researchers found that both the extract and pure CBD reduced the release of sever…

Cannabis sativa L.; cannabidiol; fibroblasts; keratinocytes; skin inflammation; wound injury.
A2019

Role of matrix metalloproteinases 2 and 9 in the development of frozen shoulder: human data and experimental analysis in a rat contracture model

Chul-Hyun Cho, Yun-Mee Lho, Ilseon Hwang, Du Hwan Kim

This study investigated the biological processes behind frozen shoulder, a condition characterized by pain and stiffness. Researchers analyzed joint capsule tissue from both patients with frozen shoulder and from a rat…

inflammationfibrosisfrozen shoulder
1A+2019

Role of fasciae in nonspecific low back pain

G Casato, Carla Stecco, R Busin

Research increasingly links the thoracolumbar fascia to non-specific low back pain. This small case study explored the idea that pain could originate elsewhere in the body's continuous fascial network. Five patients wit…

fascianonspecific low back painlimb myofascial manipulation
A2019

Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

Franchesca D Choi, Calvin T Sung, Margit L W Juhasz, Natasha Atanaskova Mesinkovsk

This systematic review examined eleven clinical trials investigating the impact of oral collagen supplements on skin health. The findings suggest that collagen hydrolysates and peptides may improve skin elasticity, hydr…

wound healingcollagenskin aging
A+++2019

Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study

Toshio Mikami, Kohei Tano, Hosung Lee, Hyowon Lee, Jonghyuk Park, Fumiaki Ohta, Tyler W LeBaron, Shigeo Ohta

This randomized, double-blind, placebo-controlled study investigated the effects of drinking hydrogen-infused water (H2 water) before exercise. Across two experiments involving both untrained and trained participants on…

exercise; fatigue; hydrogen; hydrogen water
A2019

The Primo Vascular System as a Possible Exosomal Route Across the Body: Implications for Tumor Proliferation and Metastasis

Chiara Ghiron

This literature review proposes a possible link between the primo vascular system (PVS)—a network associated with Traditional Chinese Medicine meridians—and the way cancer spreads. The theory is that exosomes, tiny vesi…

cancer microenvironment; exosomes; hyaluronic acid; primo vascular system; tumor metastasis.