Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2019
Trigger Points, Pressure Pain Hyperalgesia, and Mechanosensitivity of Neural Tissue in Women with Chronic Pelvic Pain
Pedro Fuentes-Márquez, Marie Carmen Valenza, Irene Cabrera-Martos, Ana Ríos-Sánchez, Olga Ocón-HernándezIn this case-control study, researchers compared women with chronic pelvic pain to a healthy control group. They found that women with pelvic pain had significantly more myofascial trigger points in their low back, glut…
Myofascial Pain Syndrome; Pressure Algometry; Neurodynamics; Chronic Pelvic Pain - A+2019
Anti-Inflammatory Diets and Fatigue
Ulrike Hass, Catrin Herpich, Kristina NormanThis narrative review explores the link between pro-inflammatory status and chronic disease-related fatigue in conditions such as cancer, fibromyalgia, and chronic fatigue syndrome. While evidence for individual nutrien…
anti-inflammatory nutrition; cancer; chronic fatigue; cytokines; fatigue reduction diet; inflammation; myalgic encephalomyelitis; omega-3 fatty acids; polyphenols; probiotics. - A++2019
Observation using thermography of post-operative reaction after fascial manipulation®
Joanna Fidut-Wrońska, Kamil Chołuj, Justyna Chmiel, Katarzyna Pikto-Pitkiewicz, Piotr MajcherThis study investigated whether Fascial Manipulation® causes a local increase in skin temperature, which is theorized to be part of its mechanism. Researchers used a thermal-imaging camera to measure skin temperature in…
inflammationFascial manipulationthermography - A+++2019
Tentorium Cerebelli: Muscles, Ligaments, and Dura Mater, Part 1
Bruno Bordoni, Marta Simonelli, Maria Marcella LaganaIn this narrative review, the authors describe the anatomy of the tentorium cerebelli, part of the reciprocal tension membranes that divide areas of the brain. They highlight its connections to the dura mater, ligaments…
fasciafascial systemdura matercraniotentorium cerebelli - A+++2019
Cannabis sativa L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury
Enrico Sangiovanni, Marco Fumagalli, Barbara Pacchetti, Stefano Piazza, Andrea Magnavacca, Saba Khalilpour, Gloria Melz…This in vitro study investigated how Cannabis sativa extract and its component cannabidiol (CBD) affect inflammation in human skin cells. Researchers found that both the extract and pure CBD reduced the release of sever…
Cannabis sativa L.; cannabidiol; fibroblasts; keratinocytes; skin inflammation; wound injury. - A2019
Role of matrix metalloproteinases 2 and 9 in the development of frozen shoulder: human data and experimental analysis in a rat contracture model
Chul-Hyun Cho, Yun-Mee Lho, Ilseon Hwang, Du Hwan KimThis study investigated the biological processes behind frozen shoulder, a condition characterized by pain and stiffness. Researchers analyzed joint capsule tissue from both patients with frozen shoulder and from a rat…
inflammationfibrosisfrozen shoulderimmobilizationrat; matrix metalloproteinases - 1A+2019
Role of fasciae in nonspecific low back pain
G Casato, Carla Stecco, R BusinResearch increasingly links the thoracolumbar fascia to non-specific low back pain. This small case study explored the idea that pain could originate elsewhere in the body's continuous fascial network. Five patients wit…
fascianonspecific low back painlimb myofascial manipulationfascial continuitycase series - A2019
Oral Collagen Supplementation: A Systematic Review of Dermatological Applications
Franchesca D Choi, Calvin T Sung, Margit L W Juhasz, Natasha Atanaskova MesinkovskThis systematic review examined eleven clinical trials investigating the impact of oral collagen supplements on skin health. The findings suggest that collagen hydrolysates and peptides may improve skin elasticity, hydr…
wound healingcollagenskin aging - A+++2019
Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study
Toshio Mikami, Kohei Tano, Hosung Lee, Hyowon Lee, Jonghyuk Park, Fumiaki Ohta, Tyler W LeBaron, Shigeo OhtaThis randomized, double-blind, placebo-controlled study investigated the effects of drinking hydrogen-infused water (H2 water) before exercise. Across two experiments involving both untrained and trained participants on…
exercise; fatigue; hydrogen; hydrogen water - A2019
The Primo Vascular System as a Possible Exosomal Route Across the Body: Implications for Tumor Proliferation and Metastasis
Chiara GhironThis literature review proposes a possible link between the primo vascular system (PVS)—a network associated with Traditional Chinese Medicine meridians—and the way cancer spreads. The theory is that exosomes, tiny vesi…
cancer microenvironment; exosomes; hyaluronic acid; primo vascular system; tumor metastasis. - A2019
Fascia thickness, aging and flexibility: is there an association?
Jan Wilke, Veronica Macchi, Raffaele De Caro, Carla SteccoThis study investigated how deep fascia thickness relates to age and flexibility in healthy women. Researchers compared a group of young women with a group of older women, using ultrasound to measure fascia thickness an…
connective tissue; hyaluronic acid; stiffness; myofascial; aging - A+++2019
Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology
Priya Rangan, Inyoung Choi, MinWei, Gerardo Navarrete, Esra Guen, Sebastian Brandhorst, Nobel Enyati, Gab Pasia, Daral…This study investigates how cycles of a fasting-mimicking diet (FMD) affect inflammatory bowel disease (IBD) in both mice and humans. In animal models, FMD cycles reduced intestinal inflammation, encouraged the growth o…
Crohn’s disease; fasting; fasting-mimicking diet; gut microbiota; inflammation; inflammatory bowel disease; intermittent fasting; microbiome; ulcerative colitis