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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 349–360 of 736 studies · page 30/62Since 2015
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A++2019

Effects of Different Vitamin C–Enriched Collagen Derivatives on Collagen Synthesis

Dana M Lis, Keith Baar

This study investigated how three different forms of vitamin C-enriched collagen supplements affected markers of collagen synthesis in ten active men. Participants consumed either gelatin, hydrolyzed collagen, a gummy v…

Musculoskeletalexercisegelatin
A2019

Lipedema: A Call to Action!

Giacomo Buso, Michele Depairon, Didier Tomson, Wassim Raffoul, Roberto Vettor, Lucia Mazzolai

This narrative review summarizes the current understanding of lipedema, a chronic and progressive disease primarily affecting women. It is characterized by a painful, abnormal distribution of fat in the limbs, which oft…

lymphedemalipedema; obesity
A2019

Hyaluronan/collagen hydrogels containing sulfated hyaluronan improve wound healing by sustained release of heparin-binding EGF-like growth factor

Stephan Thönes, Sandra Rother, Tom Wippold, Joanna Blaszkiewicz, Kanagasabai Balamurugan, Stephanie Moeller, Gloria Rui…

This study investigated a new type of hydrogel designed to improve wound healing. Researchers combined collagen and hyaluronan (HA), a natural component of connective tissue, with a growth factor that stimulates skin ce…

Biomimetic material; Extracellular matrix (ECM); Fibroblasts; Heparin-binding epidermal growth factor-like growth factor (HB-EGF); Hyaluronan; Hydrogel; Sulfated hyaluronan; Surface plasmon resonance; Wound healing.
A++2019

Local Vibration Stimuli Induce Mechanical Stress-Induced Factors and Facilitate Recovery From Immobilization-Induced Oxidative Myofiber Atrophy in Rats

Fusako Usuki, Masatake Fujimura, Atsushi Nakamura, Jiro Nakano, Minoru Okita, Itsuro Higuchi

This study on rats investigated whether local vibration could help muscles recover after being immobilized. Researchers put a cast on one hindlimb of the rats for a week to induce muscle atrophy. After removing the cast…

YAP1; local vibration; mechano-growth factor; mechanotransduction; oxidative myofiber atrophy; satellite cell; therapeutics.
A++2019

Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients

Stephan F E Praet, Craig R Purdam, Marijke Welvaert, Nicole Vlahovich, Gregg Lovell, Louise M Burke, Jamie E Gaida, Sil…

This pilot study investigated whether supplementing with specific collagen peptides could improve symptoms for patients with chronic Achilles tendinopathy. Participants combined a calf-strengthening program with either…

achilles tendon; microvessels; contrast-enhanced ultrasound; hydrolysed collagen supplementation
B2019

Modeling and simulation of musculoskeletal system of human lower limb based on tensegrity structure

Zhanxi Wang, Chaoran Yang, Kang Feng, Xiansheng Qin

Researchers created a computer model of the human lower limb's musculoskeletal system using tensegrity principles, which balance tension and compression. Using an established muscle model (the Hill model), they simulate…

Tensegrity structure; lower limb model; motion analysis; gait simulation
A2019

Where is your head? Perception of relative position of the head on a wielded object

Jeffrey B Wagman, Takahiro Higuchi

This study explored how we perceive our body's position relative to an object we are holding or balancing. Researchers specifically tested this by having participants "wield" an object with their head, a body part not t…

Haptics . Perception and action . Touch
A++2019

8 natural supplements to help fight inflammation

Zawn Villines

Inflammation is a natural response to injury or infection, but when it becomes chronic, it can lead to long-term pain and tissue damage. This article reviews several natural supplements that may help the body manage chr…

inflammationomega-3curcumin
B2019

Hyaluronan fragments produced during tissue injury: A signal amplifying the inflammatory response

Angela Avenoso, Giuseppe Bruschetta, Angela D'Ascola, Michele Scuruchi, Giuseppe Mandraffino, Rosa Gullace, Antonino Sa…

This narrative review examines how fragments of hyaluronan (HA), a major component of the extracellular matrix, contribute to inflammation. During tissue injury, large HA molecules are broken down into smaller pieces. E…

Hyaluronan fragments NF-kB TLR-4 Cytokines Tissue damage Inflammation Hyaluronan degradation
1A+2019

Fascia Is Able to Actively Contract and May Thereby Influence Musculoskeletal Dynamics: A Histochemical and Mechanographic Investigation

Robert Schleip, G Gabbiani, Jan Wilke, I Naylor, B Hinz, A Zorn, Heike Jäger, R Breul, S Schreiner, Werner Klingler

This study investigated whether fascia can actively contract, challenging the traditional view of it as a passive tissue. Researchers examined human and rat fascial samples for the presence of contractile cells called m…

Connective tissuestiffnessmyofibroblasts
A2019

Experimental myofascial trigger point creation in rodents

Ramon Margalef, Marc Sisquella, Marc Bosque, Clara Romeu, Orlando Mayoral, Sonia Monterde, Mercedes Priego, Rafael Guer…

This animal study investigated how myofascial trigger points might form. Researchers treated mice and rats with a substance that increases nerve signals to the muscles, mimicking a state of high neurotransmission. This…

animal model; endplate noise; myofascial pain syndrome; myofascial trigger point; spontaneous acetylcholine release
A2019

Anatomy, Fascia

Bruno Bordoni, Navid Mahabadi, Matthew Varacallo

This resource provides an overview of the anatomy of fascia. As the full text has not yet been reviewed, this summary is based on the title alone. The entry likely covers the structural and functional aspects of fascial…

fascia