Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesHyaluronan/collagen hydrogels containing sulfated hyaluronan improve wound healing by sustained release of heparin-binding EGF-like growth factor
This study investigated a new type of hydrogel designed to improve wound healing. Researchers combined collagen and hyaluronan (HA), a natural component of connective tissue, with a growth factor that stimulates skin ce…
Anti-Inflammatory Diets and Fatigue
This narrative review explores the link between pro-inflammatory status and chronic disease-related fatigue in conditions such as cancer, fibromyalgia, and chronic fatigue syndrome. While evidence for individual nutrien…
Biotensegrity or Fascintegrity
In this theoretical review, the authors question the popular "biotensegrity" model for describing the body's mechanics. They argue the model is incomplete because it fails to account for crucial factors like bodily flui…
A History of Fascia
This historiographic review surveys how the anatomical term "fascia" has been portrayed throughout history. The authors found that its meaning has varied considerably during the 400 years the term has been used in Engli…
Vitamin C Inhibits Triple-Negative Breast Cancer Metastasis by Affecting the Expression of YAP1 and Synaptopodin 2
In this study using cell cultures and animal models, researchers investigated how vitamin C might inhibit the spread of triple-negative breast cancer (TNBC). They found that vitamin C, at concentrations achievable throu…
Involvement of Acid-Sensing Ion Channel 1b in the Development of Acid-Induced Chronic Muscle Pain
In this animal study, researchers investigated the role of a specific ion channel, called ASIC1b, in the development of chronic muscle pain. They created a fibromyalgia-like condition by injecting acid into the leg musc…
Ketogenic Diet and Microbiota: Friends or Enemies
This narrative review explores the relationship between the very low-carbohydrate ketogenic diet (VLCKD) and the gut microbiota. The community of microbes in our gut is a dynamic entity known to play a fundamental role…
Modelling Cell Origami via a Tensegrity Model of the Cytoskeleton in Adherent Cells
Researchers created a computer model to better understand "cell origami," a technique where the natural pulling forces of cells are used to fold tiny structures. This model represents the cell's internal framework, or c…
3D volumetric MR arthrographic assessment of shoulder joint capacity in patients with primary adhesive capsulitis
This study used 3D MR arthrography to measure and compare shoulder joint volume in patients with primary adhesive capsulitis (frozen shoulder) against a healthy control group. Researchers found that the patient group ha…
The Primo Vascular System as a Possible Exosomal Route Across the Body: Implications for Tumor Proliferation and Metastasis
This literature review proposes a possible link between the primo vascular system (PVS)—a network associated with Traditional Chinese Medicine meridians—and the way cancer spreads. The theory is that exosomes, tiny vesi…
The neural basis of the senses of effort, force and heaviness
This narrative review explores how we sense effort, force, and heaviness during muscle contraction. Traditionally, these sensations were thought to originate in the brain from copies of motor commands. However, new evid…
Experimental myofascial trigger point creation in rodents
This animal study investigated how myofascial trigger points might form. Researchers treated mice and rats with a substance that increases nerve signals to the muscles, mimicking a state of high neurotransmission. This…