Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- 1A+2019
Fascia Is Able to Actively Contract and May Thereby Influence Musculoskeletal Dynamics: A Histochemical and Mechanographic Investigation
Robert Schleip, G Gabbiani, Jan Wilke, I Naylor, B Hinz, A Zorn, Heike Jäger, R Breul, S Schreiner, Werner KlinglerThis study investigated whether fascia can actively contract, challenging the traditional view of it as a passive tissue. Researchers examined human and rat fascial samples for the presence of contractile cells called m…
Connective tissuestiffnessmyofibroblastscontractilitycontracture - A+++2019
Tentorium Cerebelli: the Bridge Between the Central and Peripheral Nervous System, Part 2
Bruno Bordoni, Marta Simonelli, Maria Marcella LaganaThis article, the second in a series, describes the tentorium cerebelli—a meningeal structure related to the skull, nervous system, and cervical spine. The authors discuss its complex relationships, including its neurol…
fasciapaincraniotentorium cerebellivenous circulation - A++2019
Local Vibration Stimuli Induce Mechanical Stress-Induced Factors and Facilitate Recovery From Immobilization-Induced Oxidative Myofiber Atrophy in Rats
Fusako Usuki, Masatake Fujimura, Atsushi Nakamura, Jiro Nakano, Minoru Okita, Itsuro HiguchiThis study on rats investigated whether local vibration could help muscles recover after being immobilized. Researchers put a cast on one hindlimb of the rats for a week to induce muscle atrophy. After removing the cast…
YAP1; local vibration; mechano-growth factor; mechanotransduction; oxidative myofiber atrophy; satellite cell; therapeutics. - B2019
Hyaluronan fragments produced during tissue injury: A signal amplifying the inflammatory response
Angela Avenoso, Giuseppe Bruschetta, Angela D'Ascola, Michele Scuruchi, Giuseppe Mandraffino, Rosa Gullace, Antonino Sa…This narrative review examines how fragments of hyaluronan (HA), a major component of the extracellular matrix, contribute to inflammation. During tissue injury, large HA molecules are broken down into smaller pieces. E…
Hyaluronan fragments NF-kB TLR-4 Cytokines Tissue damage Inflammation Hyaluronan degradation - A2019
Anatomy, Fascia
Bruno Bordoni, Navid Mahabadi, Matthew VaracalloThis resource provides an overview of the anatomy of fascia. As the full text has not yet been reviewed, this summary is based on the title alone. The entry likely covers the structural and functional aspects of fascial…
fascia - A2019
Experimental myofascial trigger point creation in rodents
Ramon Margalef, Marc Sisquella, Marc Bosque, Clara Romeu, Orlando Mayoral, Sonia Monterde, Mercedes Priego, Rafael Guer…This animal study investigated how myofascial trigger points might form. Researchers treated mice and rats with a substance that increases nerve signals to the muscles, mimicking a state of high neurotransmission. This…
animal model; endplate noise; myofascial pain syndrome; myofascial trigger point; spontaneous acetylcholine release - A2019
Myofascial Chains of the Upper Limb: A Systematic Review of Anatomical Studies
JAN WILKE, FRIEDER KRAUSEThis systematic review compiled research to determine if myofascial chains, previously identified in the trunk and lower limbs, also exist in the upper limb. Analyzing 13 anatomical dissection studies, the authors found…
continuity; fascia; force transmission; muscles; cadavers; connective tissue; myofascial chains - A++2019
Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients
Stephan F E Praet, Craig R Purdam, Marijke Welvaert, Nicole Vlahovich, Gregg Lovell, Louise M Burke, Jamie E Gaida, Sil…This pilot study investigated whether supplementing with specific collagen peptides could improve symptoms for patients with chronic Achilles tendinopathy. Participants combined a calf-strengthening program with either…
achilles tendon; microvessels; contrast-enhanced ultrasound; hydrolysed collagen supplementation - C2019
Modelling Cell Origami via a Tensegrity Model of the Cytoskeleton in Adherent Cells
Lili Wang, Weiyi ChenResearchers created a computer model to better understand "cell origami," a technique where the natural pulling forces of cells are used to fold tiny structures. This model represents the cell's internal framework, or c…
Tensegritycytoskeletoncell adhesioncell origami - A2019
Chronic low back pain influences trunk neuromuscular control during unstable sitting among persons with lower-limb loss
Courtney M Butowicz, Julian C Acasio, Silfies Sheri P, Maury A Nussbaum, Brad D HendershotPeople with lower-limb loss are at a higher risk for chronic low back pain. This study investigated whether trunk postural control differs between those with and without pain in this population. Researchers had men with…
low back painBiomechanicsPostural controlAmputation - C2019
Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models
Anne-Laure Papa, Amanda Jiang, Netanel Korin, Michelle B Chen, Erin T Langan, Anna Waterhouse, Emma Nash, Jildaz Carof,…Platelets are crucial for blood clotting but can also contribute to thrombosis and cancer metastasis. In this preclinical study, researchers created modified human platelets, called "platelet decoys," that retained thei…
Plateletplatelet decoystrombosismetastatic tumors - A++2019
A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study
Liane Bolke, Gerrit Schlippe, Joachim Gerß, Werner VossThis randomized, placebo-controlled study investigated the effects of a drinkable nutraceutical containing 2.5g of collagen peptides, vitamins, and minerals on skin health in women aged 35 and older. Over twelve weeks,…
aging; beauty; bioavailability; collagen peptides; corneometry; cutometry; high coverage [HC] collagen complex; wrinkles