Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesCollagenase Clostridium Histolyticum for the Treatment of Edematous Fibrosclerotic Panniculopathy (Cellulite): A Randomized Trial
This randomized, double-blind clinical trial evaluated the effectiveness of an enzyme injection, collagenase clostridium histolyticum (CCH), for treating cellulite. Researchers treated 375 women with moderate to severe…
Hyaluronan fragments produced during tissue injury: A signal amplifying the inflammatory response
This narrative review examines how fragments of hyaluronan (HA), a major component of the extracellular matrix, contribute to inflammation. During tissue injury, large HA molecules are broken down into smaller pieces. E…
Anatomy, Bony Pelvis and Lower Limb, Pelvic Fascia
This anatomical review describes the pelvis not as a rigid, static base, but as a dynamic structure. Applying a biotensegrity model, the authors explain how the pelvic bones are suspended within a complex web of tension…
Benefits of adding stretching to a moderate-intensity aerobic exercise programme in women with fibromyalgia: a randomized controlled trial
This randomized controlled trial investigated whether adding stretching to a moderate-intensity aerobic exercise program provided extra benefits for women with fibromyalgia. One group performed moderate aerobic exercise…
Evaluation of hyaluronan content in areas of densification compared to adjacent areas of fascia
This entry is currently a title only, so a full summary is not available. Based on the title, the researchers appear to have evaluated and compared the hyaluronan content in areas of fascial densification with the conte…
Protein synthesis rates of muscle, tendon, ligament, cartilage, and bone tissue in vivo in humans
This study measured protein synthesis rates directly in various human knee joint tissues for the first time. Researchers collected samples from muscle, tendon, ligaments, cartilage, and bone during total knee replacemen…
Biophysics of Cell-Substrate Interactions Under Shear
In this review article, the authors examine how cells adhere to surfaces and respond to mechanical forces. Cells use complex structures called focal adhesions to sense and react to their environment, including forces fr…
Stress Relaxation and Targeted Nutrition to Treat Patellar Tendinopathy
This case study outlines the rehabilitation of a professional basketball player with patellar tendinopathy. The athlete undertook a program combining gelatin ingestion with heavy isometric loading of the patellar tendon…
Active Contractile Properties of Fascia
This narrative review explores how fascia, often seen as a passive tissue, can actively contract. Researchers point to the presence of cells called myofibroblasts within the fascia, which give it the ability to change i…
Daily oral dosing of vitamin D3 using 5000 TO 50,000 international units a day in long-term hospitalized patients: Insights from a seven year experience
This observational study followed long-term hospitalized patients over seven years to evaluate the safety of high daily doses of vitamin D3. Patients received supplements ranging from 5,000 to 50,000 international units…
Stiffness and echogenicity: Development of a stiffness-echogenicity matrix for clinical problem solving
Assessing soft tissue stiffness is important for many neuromusculoskeletal conditions, but can be challenging. While ultrasound can measure a tissue's echogenicity (how it reflects sound waves), this is not directly pro…
Specific Collagen Peptides in Combination with Resistance Training Improve Body Composition and Regional Muscle Strength in Premenopausal Women: A Randomized Controlled Trial
This randomized controlled trial investigated the effects of combining resistance training with a daily intake of 15 grams of specific collagen peptides in premenopausal women. Over 12 weeks, participants trained three…