Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesHigh Cortisol and the Risk of Dementia and Alzheimer's Disease: A Review of the Literature
This literature review examines the relationship between the stress hormone cortisol and the risk of dementia and Alzheimer’s disease. The research suggests that chronically elevated cortisol levels may have deleterious…
Stiffness and echogenicity: Development of a stiffness-echogenicity matrix for clinical problem solving
Assessing soft tissue stiffness is important for many neuromusculoskeletal conditions, but can be challenging. While ultrasound can measure a tissue's echogenicity (how it reflects sound waves), this is not directly pro…
A prophylactic effect of local vibration on quadriceps muscle fatigue in non-athletic males: a randomized controlled trial study
This randomized controlled trial investigated whether local vibration could prevent muscle fatigue. Thirty healthy, non-athletic young men were divided into two groups: one received two minutes of vibration on their qua…
Glut-1 explains the evolutionary advantage of the loss of endogenous vitamin C-synthesis
Unlike many animals, humans cannot produce their own vitamin C. This study explores a potential evolutionary advantage of this loss. Researchers compared red blood cells from humans and pigs (who can make vitamin C) and…
Fascial Nomenclature: Update on Related Consensus Process
The term "fascia" is increasingly used across different health-oriented fields, but often inconsistently, which causes confusion. To address this, the Fascia Research Society established a Fascia Nomenclature Committee.…
A History of Fascia
This historiographic review surveys how the anatomical term "fascia" has been portrayed throughout history. The authors found that its meaning has varied considerably during the 400 years the term has been used in Engli…
Evaluation of the Structure of Myodural Bridges in an Equine Model of Ehlers-Danlos Syndromes
This animal study investigated myodural bridges—connective tissue links between small neck muscles and the spinal cord's outer covering (dura mater)—in horses. Researchers compared horses with a genetic connective tissu…
Existence and features of the myodural bridge in Gallus domesticus: indication of its important physiological function
In this anatomical animal study, researchers investigated the existence of the myodural bridge (MDB) in chickens. The MDB is a dense connective tissue that links muscles in the upper neck to the spinal dura mater. The i…
Extracellular matrix composition of connective tissues: a systematic review and meta-analysis
This systematic review and meta-analysis compiled data to quantify the protein composition of the extracellular matrix (ECM) in various human connective tissues. Researchers analyzed data from studies on bone, adipose t…
Bone Tissue is an Integral Part of the Fascial System
This review article proposes that bone tissue should be considered an integral part of the fascial system, a departure from the current definition. The authors support this by highlighting the shared embryological origi…
Hierarchical Hydrogel Composite Interfaces with Robust Mechanical Properties for Biomedical Applications
This review summarizes advances in hydrogel composites, materials designed to mimic the body's extracellular matrix (ECM). Cells naturally sense and respond to the mechanical properties and physical structure of the ECM…
High-dose vitamin C suppresses the invasion and metastasis of breast cancer cells via inhibiting epithelial-mesenchymal transition
This study on breast cancer cells in the lab and in mice explored how different doses of vitamin C affect cancer cell behavior. Researchers found that low and medium doses of vitamin C seemed to encourage cancer cells t…