Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesEvaluation of the Structure of Myodural Bridges in an Equine Model of Ehlers-Danlos Syndromes
This animal study investigated myodural bridges—connective tissue links between small neck muscles and the spinal cord's outer covering (dura mater)—in horses. Researchers compared horses with a genetic connective tissu…
Cannabis sativa L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury
This in vitro study investigated how Cannabis sativa extract and its component cannabidiol (CBD) affect inflammation in human skin cells. Researchers found that both the extract and pure CBD reduced the release of sever…
Ultrasound-detected connective tissue involvement in acute muscle injuries in elite athletes and return to play: The French National Institute of Sports (INSEP) study
This study examined 70 elite athletes with acute muscle injuries. Researchers used ultrasound within seven days to assess injury severity and to see if connective tissue was involved. They then tracked the time it took…
New Insights of Uterine Leiomyoma Pathogenesis: Endocannabinoid System
This study investigated the role of the endocannabinoid system in the development of uterine leiomyomas, commonly known as fibroids. Researchers analyzed tissue samples and found that the expression of specific receptor…
Role of matrix metalloproteinases 2 and 9 in the development of frozen shoulder: human data and experimental analysis in a rat contracture model
This study investigated the biological processes behind frozen shoulder, a condition characterized by pain and stiffness. Researchers analyzed joint capsule tissue from both patients with frozen shoulder and from a rat…
Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients
This pilot study investigated whether supplementing with specific collagen peptides could improve symptoms for patients with chronic Achilles tendinopathy. Participants combined a calf-strengthening program with either…
Bone Tissue is an Integral Part of the Fascial System
This review article proposes that bone tissue should be considered an integral part of the fascial system, a departure from the current definition. The authors support this by highlighting the shared embryological origi…
Hierarchical Hydrogel Composite Interfaces with Robust Mechanical Properties for Biomedical Applications
This review summarizes advances in hydrogel composites, materials designed to mimic the body's extracellular matrix (ECM). Cells naturally sense and respond to the mechanical properties and physical structure of the ECM…
Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure
This randomized controlled trial investigated whether intravenous vitamin C could help patients with sepsis and severe acute respiratory failure. Researchers gave 167 patients either a high-dose vitamin C infusion or a…
Lipedema: friend and foe
Lipedema is a chronic disorder characterized by painful, disproportionate fat accumulation in the limbs of women, and is often misdiagnosed as obesity. In this review, researchers examined both the negative ('foe') and…
Stress Relaxation and Targeted Nutrition to Treat Patellar Tendinopathy
This case study outlines the rehabilitation of a professional basketball player with patellar tendinopathy. The athlete undertook a program combining gelatin ingestion with heavy isometric loading of the patellar tendon…
Blocking around the transversalis fascia: behind the scene
This cadaver study investigated the anatomy of the transversalis fascia, a thin layer of connective tissue in the abdominal wall, to understand its role in certain nerve blocks. Through dissection and microscopic analys…