Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesVitamin C administration in the critically ill: a summary of recent meta-analyses
This 2019 publication is a summary of recent meta-analyses on the topic of vitamin C administration for critically ill patients. As the full text has not yet been reviewed, a detailed summary of its findings is not avai…
Cannabis sativa L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury
This in vitro study investigated how Cannabis sativa extract and its component cannabidiol (CBD) affect inflammation in human skin cells. Researchers found that both the extract and pure CBD reduced the release of sever…
The Other Side of the Fascia: The SmoothMuscle Part 1
This theoretical article challenges the standard definition of fascia. Traditionally, fascia is considered connective tissue originating from two embryonic layers, the mesoderm and ectoderm. The authors propose expandin…
Chronic low back pain influences trunk neuromuscular control during unstable sitting among persons with lower-limb loss
People with lower-limb loss are at a higher risk for chronic low back pain. This study investigated whether trunk postural control differs between those with and without pain in this population. Researchers had men with…
Lipedema: A Call to Action!
This narrative review summarizes the current understanding of lipedema, a chronic and progressive disease primarily affecting women. It is characterized by a painful, abnormal distribution of fat in the limbs, which oft…
Lymphatic pump manipulation in patients with chronic obstructive pulmonary disease
This narrative review examines the use of lymphatic pump manipulation for patients with chronic obstructive pulmonary disease (COPD). COPD is characterized by persistent inflammation, and lymphatic techniques aim to red…
Cannabidiol differentially regulates basal and LPS-induced inflammatory responses in macrophages, lung epithelial cells, and fibroblasts
This laboratory study investigated how cannabidiol (CBD) influences inflammatory responses in lung epithelial cells, fibroblasts, and immune cells. The researchers found that CBD can reduce inflammation triggered by ext…
Fascial Entrapment Neuropathy
This narrative review explores how fascia can contribute to nerve entrapment syndromes, which cause pain, sensory abnormalities, and weakness. The authors describe how nerves are surrounded by a microenvironment of conn…
Cranial osteopathy: Obscurantism and Enlightenment
In this reflective article, the authors discuss the controversial aspects of cranial osteopathy. They address common objections, such as the idea that the cranial bones are immobile in adults and that an operator's hand…
The Other Side of the Fascia: Visceral Fascia, Part 2
This editorial, part two of a series, argues for including certain internal organs (viscera) within the definition of fascia. From an osteopathic perspective, the authors suggest that understanding these organs as fasci…
Anti-Inflammatory Diets and Fatigue
This narrative review explores the link between pro-inflammatory status and chronic disease-related fatigue in conditions such as cancer, fibromyalgia, and chronic fatigue syndrome. While evidence for individual nutrien…
Involvement of Acid-Sensing Ion Channel 1b in the Development of Acid-Induced Chronic Muscle Pain
In this animal study, researchers investigated the role of a specific ion channel, called ASIC1b, in the development of chronic muscle pain. They created a fibromyalgia-like condition by injecting acid into the leg musc…